31DR
Rigid body fitted Mycobacterium smegmatis RNA polymerase in complex with HelD, SigA and RbpA in State II
Functional Information from PROSITE/UniProt
| site_id | PS00715 |
| Number of Residues | 14 |
| Details | SIGMA70_1 Sigma-70 factors family signature 1. DLIQeGnLGLIrAV |
| Chain | Residue | Details |
| F | ASP257-VAL270 |
| site_id | PS00716 |
| Number of Residues | 27 |
| Details | SIGMA70_2 Sigma-70 factors family signature 2. TldEIGqvygVTrerIrQIEsktMskL |
| Chain | Residue | Details |
| F | THR426-LEU452 |
| site_id | PS00867 |
| Number of Residues | 8 |
| Details | CPSASE_2 Carbamoyl-phosphate synthase subdomain signature 2. LLEANLRL |
| Chain | Residue | Details |
| F | LEU233-LEU240 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 450 |
| Details | Region: {"description":"Alpha N-terminal domain (alpha-NTD)","evidences":[{"source":"HAMAP-Rule","id":"MF_00059","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 11 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01322","evidenceCode":"ECO:0000255"},{"source":"PDB","id":"6YXU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6YYS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6Z11","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 34 |
| Details | Region: {"description":"Sigma-70 factor domain-1","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | Motif: {"description":"Interaction with polymerase core subunit RpoC","evidences":[{"source":"HAMAP-Rule","id":"MF_00963","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 414 |
| Details | Domain: {"description":"UvrD-like helicase ATP-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00560","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 56 |
| Details | Coiled coil: {"evidences":[{"source":"PubMed","id":"33339823","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6YXU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6YYS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6Z11","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00560","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"33339823","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6YYS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6Z11","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
