Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0006508 | biological_process | proteolysis |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0008236 | molecular_function | serine-type peptidase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0042802 | molecular_function | identical protein binding |
| B | 0004252 | molecular_function | serine-type endopeptidase activity |
| B | 0005576 | cellular_component | extracellular region |
| B | 0006508 | biological_process | proteolysis |
| B | 0008233 | molecular_function | peptidase activity |
| B | 0008236 | molecular_function | serine-type peptidase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0042802 | molecular_function | identical protein binding |
| C | 0004252 | molecular_function | serine-type endopeptidase activity |
| C | 0005576 | cellular_component | extracellular region |
| C | 0006508 | biological_process | proteolysis |
| C | 0008233 | molecular_function | peptidase activity |
| C | 0008236 | molecular_function | serine-type peptidase activity |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0042802 | molecular_function | identical protein binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 399 |
| Chain | Residue |
| A | GLN84 |
| A | ASP124 |
| A | LEU164 |
| A | ASN166 |
| A | ILE168 |
| A | VAL170 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 400 |
| Chain | Residue |
| A | ILE218 |
| A | ASP222 |
| A | ASP225 |
| A | ASP212 |
| A | ASP214 |
| A | ASP216 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA A 401 |
| Chain | Residue |
| A | ASP214 |
| A | ASP216 |
| A | ASP222 |
| A | ASP224 |
| A | HOH607 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 402 |
| Chain | Residue |
| A | VAL108 |
| A | GLN110 |
| A | ALA227 |
| A | GLU229 |
| A | HOH447 |
| A | HOH580 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA A 403 |
| Chain | Residue |
| A | ASP119 |
| A | ASP121 |
| A | ASP314 |
| A | ASP315 |
| A | HOH604 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 404 |
| Chain | Residue |
| A | ASP372 |
| A | LEU373 |
| A | PRO375 |
| A | GLY377 |
| A | ASP379 |
| A | HOH560 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 399 |
| Chain | Residue |
| B | GLN84 |
| B | ASP124 |
| B | LEU164 |
| B | ASN166 |
| B | ILE168 |
| B | VAL170 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 400 |
| Chain | Residue |
| B | ASP212 |
| B | ASP214 |
| B | ASP216 |
| B | ILE218 |
| B | ASP222 |
| B | ASP225 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 401 |
| Chain | Residue |
| A | THR142 |
| A | HOH438 |
| B | ASP214 |
| B | ASP216 |
| B | ASP222 |
| B | ASP224 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA B 402 |
| Chain | Residue |
| B | ASP372 |
| B | LEU373 |
| B | PRO375 |
| B | GLY377 |
| B | ASP379 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 403 |
| Chain | Residue |
| B | VAL108 |
| B | GLN110 |
| B | ALA227 |
| B | GLU229 |
| B | HOH433 |
| B | HOH651 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA C 399 |
| Chain | Residue |
| C | GLN84 |
| C | ASP124 |
| C | LEU164 |
| C | ASN166 |
| C | ILE168 |
| C | VAL170 |
| site_id | BC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA C 400 |
| Chain | Residue |
| C | ASP212 |
| C | ASP214 |
| C | ASP216 |
| C | ILE218 |
| C | ASP222 |
| C | ASP225 |
| site_id | BC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA C 401 |
| Chain | Residue |
| C | ASP214 |
| C | ASP216 |
| C | ASP222 |
| C | HOH533 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA C 402 |
| Chain | Residue |
| C | ASP372 |
| C | LEU373 |
| C | PRO375 |
| C | GLY377 |
| C | ASP379 |
| C | HOH486 |
| site_id | BC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA C 403 |
| Chain | Residue |
| C | VAL108 |
| C | GLN110 |
| C | ALA227 |
| C | GLU229 |
| C | HOH521 |
| C | HOH544 |
Functional Information from PROSITE/UniProt
| site_id | PS00136 |
| Number of Residues | 12 |
| Details | SUBTILASE_ASP Serine proteases, subtilase family, aspartic acid active site. VAVLDTGVdydH |
| Chain | Residue | Details |
| A | VAL111-HIS122 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 918 |
| Details | Domain: {"description":"Peptidase S8","evidences":[{"source":"PROSITE-ProRule","id":"PRU01240","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 9 |
| Details | Active site: {"description":"Charge relay system","evidences":[{"source":"PROSITE-ProRule","id":"PRU01240","evidenceCode":"ECO:0000255"}]} |
