Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0006400 | biological_process | tRNA modification |
| A | 0008033 | biological_process | tRNA processing |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0008175 | molecular_function | tRNA methyltransferase activity |
| A | 0030488 | biological_process | tRNA methylation |
| A | 0031591 | biological_process | wybutosine biosynthetic process |
| A | 0032259 | biological_process | methylation |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005739 | cellular_component | mitochondrion |
| B | 0006400 | biological_process | tRNA modification |
| B | 0008033 | biological_process | tRNA processing |
| B | 0008168 | molecular_function | methyltransferase activity |
| B | 0008175 | molecular_function | tRNA methyltransferase activity |
| B | 0030488 | biological_process | tRNA methylation |
| B | 0031591 | biological_process | wybutosine biosynthetic process |
| B | 0032259 | biological_process | methylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE SAH A 801 |
| Chain | Residue |
| A | ILE27 |
| A | GLY117 |
| A | ASP146 |
| A | TYR147 |
| A | LEU150 |
| A | CYS195 |
| A | ASP196 |
| A | LEU197 |
| A | ASN198 |
| A | GLU224 |
| A | VAL225 |
| A | GLN28 |
| A | SER226 |
| A | HOH837 |
| A | HOH843 |
| A | HOH1193 |
| A | HOH1194 |
| A | THR30 |
| A | ASN31 |
| A | SER34 |
| A | LYS38 |
| A | ARG88 |
| A | GLY115 |
| A | CYS116 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE CIT A 802 |
| Chain | Residue |
| A | LYS484 |
| A | ILE524 |
| A | PHE525 |
| A | EDO696 |
| A | HOH907 |
| A | HOH1014 |
| A | HOH1018 |
| A | HOH1020 |
| A | HOH1079 |
| A | HOH1166 |
| B | LYS326 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 696 |
| Chain | Residue |
| A | LEU486 |
| A | SER487 |
| A | HIS488 |
| A | HOH718 |
| A | CIT802 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 697 |
| Chain | Residue |
| A | GLY615 |
| A | LEU655 |
| A | HOH755 |
| A | HOH933 |
| A | HOH1227 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 698 |
| Chain | Residue |
| A | VAL438 |
| A | ASP469 |
| A | HOH768 |
| B | VAL438 |
| B | ASP469 |
| B | HOH717 |
| site_id | AC6 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE SAH B 801 |
| Chain | Residue |
| B | SER34 |
| B | ILE35 |
| B | LYS38 |
| B | ARG88 |
| B | GLY115 |
| B | CYS116 |
| B | GLY117 |
| B | ASP146 |
| B | TYR147 |
| B | CYS195 |
| B | ASP196 |
| B | LEU197 |
| B | ASN198 |
| B | GLU224 |
| B | VAL225 |
| B | SER226 |
| B | HOH719 |
| B | HOH888 |
| B | HOH951 |
| B | HOH1122 |
| site_id | AC7 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE CIT B 802 |
| Chain | Residue |
| B | LYS484 |
| B | ILE524 |
| B | PHE525 |
| B | EDO696 |
| B | HOH763 |
| B | HOH796 |
| B | HOH814 |
| B | HOH891 |
| B | HOH974 |
| B | HOH1159 |
| B | HOH1309 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 696 |
| Chain | Residue |
| B | LEU486 |
| B | SER487 |
| B | HIS488 |
| B | HOH716 |
| B | CIT802 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 697 |
| Chain | Residue |
| B | PRO264 |
| B | GLY615 |
| B | MET654 |
| B | LEU655 |
| B | HOH726 |
| B | HOH918 |
| B | HOH1072 |
| site_id | BC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EDO B 698 |
| Chain | Residue |
| B | HOH794 |
| B | HOH866 |
| B | HOH876 |
| B | HOH1419 |
| B | ASP392 |
| B | HIS443 |
| B | HIS493 |
| B | GLN601 |
| B | HOH776 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton donor; for both methylation and methoxycarbonylation activities => ECO:0000269|PubMed:19287006 |
| Chain | Residue | Details |
| A | ARG88 | |
| B | ARG88 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton acceptor; for methoxycarbonylation activity => ECO:0000305|PubMed:19287006 |
| Chain | Residue | Details |
| A | TYR229 | |
| B | TYR229 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | LYS38 | |
| B | ASP146 | |
| B | ASP196 | |
| B | GLU224 | |
| A | ARG88 | |
| A | GLY115 | |
| A | ASP146 | |
| A | ASP196 | |
| A | GLU224 | |
| B | LYS38 | |
| B | ARG88 | |
| B | GLY115 | |
