2ZVV
Crystal structure of Proliferating cellular nuclear antigen 1 and Short peptide from human P21
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005730 | cellular_component | nucleolus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006260 | biological_process | DNA replication |
| A | 0006272 | biological_process | leading strand elongation |
| A | 0006275 | biological_process | regulation of DNA replication |
| A | 0006298 | biological_process | mismatch repair |
| A | 0019985 | biological_process | translesion synthesis |
| A | 0030337 | molecular_function | DNA polymerase processivity factor activity |
| A | 0043626 | cellular_component | PCNA complex |
| A | 0051726 | biological_process | regulation of cell cycle |
| B | 0003677 | molecular_function | DNA binding |
| B | 0005515 | molecular_function | protein binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0005730 | cellular_component | nucleolus |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006260 | biological_process | DNA replication |
| B | 0006272 | biological_process | leading strand elongation |
| B | 0006275 | biological_process | regulation of DNA replication |
| B | 0006298 | biological_process | mismatch repair |
| B | 0019985 | biological_process | translesion synthesis |
| B | 0030337 | molecular_function | DNA polymerase processivity factor activity |
| B | 0043626 | cellular_component | PCNA complex |
| B | 0051726 | biological_process | regulation of cell cycle |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 901 |
| Chain | Residue |
| A | ASP156 |
| A | ALA208 |
| A | ARG210 |
| A | LYS254 |
| A | HOH1013 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 911 |
| Chain | Residue |
| B | HOH1029 |
| B | HOH1207 |
| B | ASP156 |
| B | ALA208 |
| B | ARG210 |
| B | LYS254 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 38 |
| Details | DNA binding: {"evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphothreonine; by PKA, PKB/AKT1, PIM1 and PIM2","evidences":[{"source":"PubMed","id":"10753973","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11463845","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12431783","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16982699","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20307683","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine; by PKC and NUAK1","evidences":[{"source":"PubMed","id":"10753973","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25329316","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
