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2ZV6

Crystal structure of human squamous cell carcinoma antigen 1

Functional Information from GO Data
ChainGOidnamespacecontents
A0001618molecular_functionvirus receptor activity
A0002020molecular_functionprotease binding
A0004867molecular_functionserine-type endopeptidase inhibitor activity
A0004869molecular_functioncysteine-type endopeptidase inhibitor activity
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0005634cellular_componentnucleus
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0005886cellular_componentplasma membrane
A0008284biological_processpositive regulation of cell population proliferation
A0010466biological_processnegative regulation of peptidase activity
A0010718biological_processpositive regulation of epithelial to mesenchymal transition
A0010950biological_processpositive regulation of endopeptidase activity
A0010951biological_processnegative regulation of endopeptidase activity
A0030335biological_processpositive regulation of cell migration
A0031410cellular_componentcytoplasmic vesicle
A0031982cellular_componentvesicle
A0035425biological_processautocrine signaling
A0035578cellular_componentazurophil granule lumen
A0038001biological_processparacrine signaling
A0043086biological_processnegative regulation of catalytic activity
A0043508biological_processnegative regulation of JUN kinase activity
A0045861biological_processnegative regulation of proteolysis
A0046718biological_processsymbiont entry into host cell
A0070062cellular_componentextracellular exosome
B0001618molecular_functionvirus receptor activity
B0002020molecular_functionprotease binding
B0004867molecular_functionserine-type endopeptidase inhibitor activity
B0004869molecular_functioncysteine-type endopeptidase inhibitor activity
B0005515molecular_functionprotein binding
B0005576cellular_componentextracellular region
B0005615cellular_componentextracellular space
B0005634cellular_componentnucleus
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0005886cellular_componentplasma membrane
B0008284biological_processpositive regulation of cell population proliferation
B0010466biological_processnegative regulation of peptidase activity
B0010718biological_processpositive regulation of epithelial to mesenchymal transition
B0010950biological_processpositive regulation of endopeptidase activity
B0010951biological_processnegative regulation of endopeptidase activity
B0030335biological_processpositive regulation of cell migration
B0031410cellular_componentcytoplasmic vesicle
B0031982cellular_componentvesicle
B0035425biological_processautocrine signaling
B0035578cellular_componentazurophil granule lumen
B0038001biological_processparacrine signaling
B0043086biological_processnegative regulation of catalytic activity
B0043508biological_processnegative regulation of JUN kinase activity
B0045861biological_processnegative regulation of proteolysis
B0046718biological_processsymbiont entry into host cell
B0070062cellular_componentextracellular exosome
C0001618molecular_functionvirus receptor activity
C0002020molecular_functionprotease binding
C0004867molecular_functionserine-type endopeptidase inhibitor activity
C0004869molecular_functioncysteine-type endopeptidase inhibitor activity
C0005515molecular_functionprotein binding
C0005576cellular_componentextracellular region
C0005615cellular_componentextracellular space
C0005634cellular_componentnucleus
C0005737cellular_componentcytoplasm
C0005829cellular_componentcytosol
C0005886cellular_componentplasma membrane
C0008284biological_processpositive regulation of cell population proliferation
C0010466biological_processnegative regulation of peptidase activity
C0010718biological_processpositive regulation of epithelial to mesenchymal transition
C0010950biological_processpositive regulation of endopeptidase activity
C0010951biological_processnegative regulation of endopeptidase activity
C0030335biological_processpositive regulation of cell migration
C0031410cellular_componentcytoplasmic vesicle
C0031982cellular_componentvesicle
C0035425biological_processautocrine signaling
C0035578cellular_componentazurophil granule lumen
C0038001biological_processparacrine signaling
C0043086biological_processnegative regulation of catalytic activity
C0043508biological_processnegative regulation of JUN kinase activity
C0045861biological_processnegative regulation of proteolysis
C0046718biological_processsymbiont entry into host cell
C0070062cellular_componentextracellular exosome
Functional Information from PROSITE/UniProt
site_idPS00284
Number of Residues11
DetailsSERPIN Serpins signature. FHCNHPFLFfI
ChainResidueDetails
APHE363-ILE373

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsSITE: Reactive bond
ChainResidueDetails
ASER354
BSER354
CSER354

226707

PDB entries from 2024-10-30

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