2ZTI
Structures of dimeric nonstandard nucleotide triphosphate pyrophosphatase from Pyrococcus horikoshii OT3: functional significance of interprotomer conformational changes
Replaces: 2EHKFunctional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000166 | molecular_function | nucleotide binding |
A | 0005737 | cellular_component | cytoplasm |
A | 0009117 | biological_process | nucleotide metabolic process |
A | 0009143 | biological_process | nucleoside triphosphate catabolic process |
A | 0009146 | biological_process | purine nucleoside triphosphate catabolic process |
A | 0016787 | molecular_function | hydrolase activity |
A | 0017111 | molecular_function | ribonucleoside triphosphate phosphatase activity |
A | 0035870 | molecular_function | dITP diphosphatase activity |
A | 0036220 | molecular_function | ITP diphosphatase activity |
A | 0036222 | molecular_function | XTP diphosphatase activity |
A | 0046872 | molecular_function | metal ion binding |
A | 0047429 | molecular_function | nucleoside triphosphate diphosphatase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE MN A 187 |
Chain | Residue |
A | GLU36 |
A | ASP65 |
A | HOH189 |
A | HOH243 |
A | HOH259 |
A | HOH260 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_01405","evidenceCode":"ECO:0000255"}]} |
Chain | Residue | Details |
site_id | SWS_FT_FI2 |
Number of Residues | 11 |
Details | Binding site: {"evidences":[{"source":"PubMed","id":"18062990","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"DEC-2006","submissionDatabase":"PDB data bank","title":"Structure of nucleotide triphosphate pyrophosphatase from Pyrococcus horikoshii OT3.","authoringGroup":["RIKEN structural genomics initiative (RSGI)"]}},{"source":"PDB","id":"2DVO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2E5X","evidenceCode":"ECO:0007744"}]} |
Chain | Residue | Details |
site_id | SWS_FT_FI3 |
Number of Residues | 2 |
Details | Binding site: {"evidences":[{"source":"PubMed","id":"18062990","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"2ZTI","evidenceCode":"ECO:0007744"}]} |
Chain | Residue | Details |