2ZPH
Complex of Fe-type nitrile hydratase with tert-butylisonitrile, photo-activated for 340min at 293K
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003824 | molecular_function | catalytic activity |
A | 0016829 | molecular_function | lyase activity |
A | 0018822 | molecular_function | nitrile hydratase activity |
A | 0046872 | molecular_function | metal ion binding |
A | 0046914 | molecular_function | transition metal ion binding |
A | 0080109 | molecular_function | indole-3-acetonitrile nitrile hydratase activity |
B | 0016829 | molecular_function | lyase activity |
B | 0018822 | molecular_function | nitrile hydratase activity |
B | 0046914 | molecular_function | transition metal ion binding |
B | 0080109 | molecular_function | indole-3-acetonitrile nitrile hydratase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE FE A 300 |
Chain | Residue |
A | CYS109 |
A | CSD112 |
A | SER113 |
A | CSO114 |
A | TB0301 |
site_id | AC2 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE TB0 A 301 |
Chain | Residue |
A | HOH604 |
B | TYR37 |
B | TYR72 |
A | CSD112 |
A | SER113 |
A | CSO114 |
A | FE300 |
site_id | AC3 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE MG A 602 |
Chain | Residue |
A | HOH605 |
A | HOH606 |
A | HOH607 |
A | HOH608 |
A | HOH609 |
A | HOH610 |
site_id | AC4 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE MG A 603 |
Chain | Residue |
A | HOH611 |
A | HOH612 |
A | HOH613 |
A | HOH614 |
A | HOH615 |
A | HOH616 |
site_id | AC5 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE MG B 601 |
Chain | Residue |
B | HOH1902 |
B | HOH1903 |
B | HOH1904 |
B | HOH1905 |
B | HOH1906 |
B | HOH1907 |
site_id | AC6 |
Number of Residues | 11 |
Details | BINDING SITE FOR RESIDUE TRS B1901 |
Chain | Residue |
A | ARG138 |
A | GLU139 |
B | GLN11 |
B | PRO137 |
B | ASP193 |
B | THR194 |
B | ASP195 |
B | HOH2009 |
B | HOH2010 |
B | HOH2012 |
B | HOH2014 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 4 |
Details | BINDING: BINDING => ECO:0000269|PubMed:9586994, ECO:0007744|PDB:2AHJ |
Chain | Residue | Details |
A | CYS109 | |
A | CSD112 | |
A | SER113 | |
A | CSO114 |
site_id | SWS_FT_FI2 |
Number of Residues | 1 |
Details | MOD_RES: Cysteine sulfinic acid (-SO2H) => ECO:0000269|PubMed:9368004, ECO:0000269|PubMed:9586994 |
Chain | Residue | Details |
A | CSD112 |
site_id | SWS_FT_FI3 |
Number of Residues | 1 |
Details | MOD_RES: Cysteine sulfenic acid (-SOH) => ECO:0000269|PubMed:9586994 |
Chain | Residue | Details |
A | CSO114 |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1ahj |
Chain | Residue | Details |
B | ARG56 |
site_id | MCSA1 |
Number of Residues | 3 |
Details | M-CSA 57 |
Chain | Residue | Details |
B | ARG56 | electrostatic stabiliser, proton acceptor, proton donor |
B | TYR72 | proton acceptor, proton donor |
B | TYR76 | increase acidity, increase basicity |
A | CSO114 | electrofuge, metal ligand, nucleophile, proton acceptor, proton donor |