2ZNW
Crystal Structure of ScFv10 in Complex with Hen Egg Lysozyme
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005886 | cellular_component | plasma membrane |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005886 | cellular_component | plasma membrane |
| Y | 0003796 | molecular_function | lysozyme activity |
| Y | 0005515 | molecular_function | protein binding |
| Y | 0005576 | cellular_component | extracellular region |
| Y | 0005737 | cellular_component | cytoplasm |
| Y | 0005783 | cellular_component | endoplasmic reticulum |
| Y | 0005794 | cellular_component | Golgi apparatus |
| Y | 0016231 | molecular_function | beta-N-acetylglucosaminidase activity |
| Y | 0016998 | biological_process | cell wall macromolecule catabolic process |
| Y | 0031640 | biological_process | killing of cells of another organism |
| Y | 0042742 | biological_process | defense response to bacterium |
| Y | 0042802 | molecular_function | identical protein binding |
| Y | 0050829 | biological_process | defense response to Gram-negative bacterium |
| Y | 0050830 | biological_process | defense response to Gram-positive bacterium |
| Y | 0051672 | biological_process | obsolete catabolism by organism of cell wall peptidoglycan in other organism |
| Z | 0003796 | molecular_function | lysozyme activity |
| Z | 0005515 | molecular_function | protein binding |
| Z | 0005576 | cellular_component | extracellular region |
| Z | 0005737 | cellular_component | cytoplasm |
| Z | 0005783 | cellular_component | endoplasmic reticulum |
| Z | 0005794 | cellular_component | Golgi apparatus |
| Z | 0016231 | molecular_function | beta-N-acetylglucosaminidase activity |
| Z | 0016998 | biological_process | cell wall macromolecule catabolic process |
| Z | 0031640 | biological_process | killing of cells of another organism |
| Z | 0042742 | biological_process | defense response to bacterium |
| Z | 0042802 | molecular_function | identical protein binding |
| Z | 0050829 | biological_process | defense response to Gram-negative bacterium |
| Z | 0050830 | biological_process | defense response to Gram-positive bacterium |
| Z | 0051672 | biological_process | obsolete catabolism by organism of cell wall peptidoglycan in other organism |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 1PG B 243 |
| Chain | Residue |
| B | HIS34 |
| B | TYR36 |
| B | LYS49 |
| B | GLN89 |
| B | SER91 |
| B | TRP220 |
| B | ASP221 |
| Z | ASN93 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE 1PG A 243 |
| Chain | Residue |
| A | TYR36 |
| A | LYS49 |
| A | GLN89 |
| A | SER91 |
| A | TRP220 |
| A | ASP221 |
| Y | CYS76 |
| Y | ASN93 |
| A | HIS34 |
Functional Information from PROSITE/UniProt
| site_id | PS00128 |
| Number of Residues | 19 |
| Details | GLYCOSYL_HYDROL_F22_1 Glycosyl hydrolases family 22 (GH22) domain signature. CnipCsaLlssDItasvnC |
| Chain | Residue | Details |
| Y | CYS76-CYS94 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI2 |
| Number of Residues | 256 |
| Details | Domain: {"description":"C-type lysozyme","evidences":[{"source":"PROSITE-ProRule","id":"PRU00680","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Active site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 132l |
| Chain | Residue | Details |
| Y | GLU35 | |
| Y | ASP52 |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 132l |
| Chain | Residue | Details |
| Z | GLU35 | |
| Z | ASP52 |
| site_id | MCSA1 |
| Number of Residues | 6 |
| Details | M-CSA 203 |
| Chain | Residue | Details |
| B | TRP35 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| B | LEU46 | |
| B | ILE48 | |
| B | TYR50 | |
| B | SER52 | covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, polar/non-polar interaction |
| B | PRO59 |
| site_id | MCSA2 |
| Number of Residues | 6 |
| Details | M-CSA 203 |
| Chain | Residue | Details |
