2ZNS

Crystal structure of the ligand-binding core of the human ionotropic glutamate receptor, GluR5, in complex with glutamate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0015276	molecular_function	ligand-gated monoatomic ion channel activity
A	0016020	cellular_component	membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	BINDING SITE FOR RESIDUE GLU A 301

Chain	Residue
A	HOH4
A	SER674
A	THR675
A	TYR749
A	HOH5
A	HOH37
A	TYR474
A	PRO501
A	LEU502
A	THR503
A	ARG508
A	GLY673

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	BINDING: BINDING => ECO:0000269|PubMed:21893069, ECO:0007744|PDB:2ZNS, ECO:0007744|PDB:3FUZ

Chain	Residue	Details
A	PRO501
A	THR503
A	ARG508
A	SER674
A	THR675
A	GLU723

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphoserine; by PKC => ECO:0000255

Chain	Residue	Details
A	SER695

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphothreonine; by PKC => ECO:0000255

Chain	Residue	Details
A	THR731

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site_id	SWS_FT_FI4
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
A	ASN416
A	ASN736

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