2ZNN
Human PPAR alpha ligand binding domain in complex with a synthetic agonist TIPP703
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE S44 A 901 |
| Chain | Residue |
| A | LEU247 |
| A | ILE354 |
| A | MET355 |
| A | PHE359 |
| A | HIS440 |
| A | LEU460 |
| A | TYR464 |
| A | HOH1171 |
| A | PHE273 |
| A | CYS276 |
| A | GLN277 |
| A | THR279 |
| A | SER280 |
| A | TYR314 |
| A | LEU321 |
| A | MET330 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 129 |
| Details | Region: {"description":"Required for heterodimerization with RXRA"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"19116277","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3ET1","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Site: {"description":"Essential for heterodimerization with RXRA"} |
| Chain | Residue | Details |
