2ZKM

Crystal Structure of Phospholipase C Beta 2

Functional Information from GO Data

Chain	GOid	namespace	contents
X	0004435	molecular_function	phosphatidylinositol-4,5-bisphosphate phospholipase C activity
X	0004629	molecular_function	phospholipase C activity
X	0006629	biological_process	lipid metabolic process
X	0007165	biological_process	signal transduction
X	0008081	molecular_function	phosphoric diester hydrolase activity
X	0035556	biological_process	intracellular signal transduction

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA X 800

Chain	Residue
X	ASN328
X	GLU357
X	ASP359
X	GLU408
X	HOH842
X	HOH844

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	151
Details	Domain: {"description":"PI-PLC X-box","evidences":[{"source":"PROSITE-ProRule","id":"PRU00270","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	116
Details	Domain: {"description":"PI-PLC Y-box","evidences":[{"source":"PROSITE-ProRule","id":"PRU00271","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	128
Details	Domain: {"description":"C2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00041","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	2
Details	Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00270","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	Binding site: {}

Chain

Residue

Details

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	3
Details	Annotated By Reference To The Literature 2isd

Chain	Residue	Details
X	HIS374
X	GLU357
X	HIS327

---