2ZJS
Crystal Structure of SecYE translocon from Thermus thermophilus with a Fab fragment
Functional Information from GO Data
Chain | GOid | namespace | contents |
E | 0005886 | cellular_component | plasma membrane |
E | 0006605 | biological_process | protein targeting |
E | 0006886 | biological_process | intracellular protein transport |
E | 0008320 | molecular_function | protein transmembrane transporter activity |
E | 0009306 | biological_process | protein secretion |
E | 0015031 | biological_process | protein transport |
E | 0016020 | cellular_component | membrane |
E | 0043952 | biological_process | protein transport by the Sec complex |
E | 0065002 | biological_process | intracellular protein transmembrane transport |
Y | 0005048 | molecular_function | signal sequence binding |
Y | 0005886 | cellular_component | plasma membrane |
Y | 0006605 | biological_process | protein targeting |
Y | 0006616 | biological_process | SRP-dependent cotranslational protein targeting to membrane, translocation |
Y | 0008320 | molecular_function | protein transmembrane transporter activity |
Y | 0015031 | biological_process | protein transport |
Y | 0016020 | cellular_component | membrane |
Y | 0031522 | cellular_component | cell envelope Sec protein transport complex |
Y | 0043952 | biological_process | protein transport by the Sec complex |
Y | 0065002 | biological_process | intracellular protein transmembrane transport |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE ZN L 223 |
Chain | Residue |
H | HIS43 |
L | GLU185 |
L | HIS189 |
site_id | AC2 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE ZN Y 435 |
Chain | Residue |
Y | GLU138 |
Y | ASP293 |
Functional Information from PROSITE/UniProt
site_id | PS00290 |
Number of Residues | 7 |
Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH |
Chain | Residue | Details |
L | TYR192-HIS198 |
site_id | PS00430 |
Number of Residues | 27 |
Details | TONB_DEPENDENT_REC_1 TonB-dependent receptor (TBDR) proteins signature 1. mvkafwsalqipelrqrvl................................................................................................FTLLVLAA |
Chain | Residue | Details |
Y | MET1-ALA27 |
site_id | PS00756 |
Number of Residues | 18 |
Details | SECY_2 Protein secY signature 2. WMaErITey.GIGNGtSLI |
Chain | Residue | Details |
Y | TRP170-ILE187 |
site_id | PS01067 |
Number of Residues | 29 |
Details | SECE_SEC61G Protein secE/sec61-gamma signature. YfQEaRaeLaRvtWPtreQvvegtQAILL |
Chain | Residue | Details |
E | TYR8-LEU36 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 136 |
Details | TOPO_DOM: Cytoplasmic |
Chain | Residue | Details |
Y | MET1-VAL18 | |
Y | GLN88-TYR114 | |
Y | THR176-ASN182 | |
Y | ALA232-VAL271 | |
Y | TYR324-ALA372 |
site_id | SWS_FT_FI2 |
Number of Residues | 15 |
Details | TRANSMEM: Helical; Name=1 |
Chain | Residue | Details |
Y | LEU19-ILE34 |
site_id | SWS_FT_FI3 |
Number of Residues | 75 |
Details | TOPO_DOM: Periplasmic |
Chain | Residue | Details |
Y | PRO35-PHE56 | |
Y | ALA131-VAL157 | |
Y | ARG202-LEU214 | |
Y | ALA289-PHE303 | |
Y | GLY390-HIS392 |
site_id | SWS_FT_FI4 |
Number of Residues | 30 |
Details | TRANSMEM: Discontinuously helical; Name=2 |
Chain | Residue | Details |
Y | GLY57-MET87 |
site_id | SWS_FT_FI5 |
Number of Residues | 10 |
Details | INTRAMEM: Helical; Name=Helix 2A |
Chain | Residue | Details |
Y | GLY57-PHE67 |
site_id | SWS_FT_FI6 |
Number of Residues | 3 |
Details | INTRAMEM: |
Chain | Residue | Details |
Y | GLU68-SER71 |
site_id | SWS_FT_FI7 |
Number of Residues | 15 |
Details | INTRAMEM: Helical; Name=Helix 2B |
Chain | Residue | Details |
Y | ILE72-MET87 |
site_id | SWS_FT_FI8 |
Number of Residues | 15 |
Details | TRANSMEM: Helical; Name=3 |
Chain | Residue | Details |
Y | THR115-LEU130 |
site_id | SWS_FT_FI9 |
Number of Residues | 17 |
Details | TRANSMEM: Helical; Name=4 |
Chain | Residue | Details |
Y | VAL158-ILE175 |
site_id | SWS_FT_FI10 |
Number of Residues | 18 |
Details | TRANSMEM: Helical; Name=5 |
Chain | Residue | Details |
Y | GLY183-LEU201 |
site_id | SWS_FT_FI11 |
Number of Residues | 16 |
Details | TRANSMEM: Helical; Name=6 |
Chain | Residue | Details |
Y | VAL215-MET231 |
site_id | SWS_FT_FI12 |
Number of Residues | 16 |
Details | TRANSMEM: Helical; Name=7 |
Chain | Residue | Details |
Y | ILE272-ALA288 |
site_id | SWS_FT_FI13 |
Number of Residues | 19 |
Details | TRANSMEM: Helical; Name=8 |
Chain | Residue | Details |
Y | PHE304-THR323 |
site_id | SWS_FT_FI14 |
Number of Residues | 16 |
Details | TRANSMEM: Helical; Name=9 |
Chain | Residue | Details |
Y | LEU373-THR389 |
site_id | SWS_FT_FI15 |
Number of Residues | 15 |
Details | TRANSMEM: Helical; Name=10 |
Chain | Residue | Details |
Y | SER393-ALA408 |