2ZIY

Crystal structure of squid rhodopsin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004930	molecular_function	G protein-coupled receptor activity
A	0007186	biological_process	G protein-coupled receptor signaling pathway
A	0007601	biological_process	visual perception
A	0016020	cellular_component	membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE RET A 380

Chain	Residue
A	PHE120
A	CYS186
A	MET204
A	PHE209
A	TRP274
A	LYS305

---

site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE PLM A 381

Chain	Residue
A	CYS336

---

site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PLM A 382

Chain	Residue
A	CYS337
A	SER316
A	CYS336

---

Functional Information from PROSITE/UniProt

site_id	PS00237
Number of Residues	17
Details	G_PROTEIN_RECEP_F1_1 G-protein coupled receptors family 1 signature. MSImTMAMISIDRYNvI

Chain	Residue	Details
A	MET121-ILE137

---

site_id	PS00238
Number of Residues	17
Details	OPSIN Visual pigments (opsins) retinal binding site. LPvMfAKASAihNPmiY

Chain	Residue	Details
A	LEU299-TYR315

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	24
Details	Transmembrane: {"description":"Helical; Name=1","evidences":[{"source":"PubMed","id":"18463093","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18480818","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21906602","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26024518","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	66
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"18463093","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18480818","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21906602","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26024518","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	26
Details	Transmembrane: {"description":"Helical; Name=2","evidences":[{"source":"PubMed","id":"18463093","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18480818","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21906602","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26024518","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	46
Details	Topological domain: {"description":"Extracellular","evidences":[{"source":"PubMed","id":"18463093","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18480818","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21906602","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26024518","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	21
Details	Transmembrane: {"description":"Helical; Name=3","evidences":[{"source":"PubMed","id":"18463093","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18480818","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21906602","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26024518","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	20
Details	Transmembrane: {"description":"Helical; Name=4","evidences":[{"source":"PubMed","id":"18463093","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18480818","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21906602","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26024518","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	24
Details	Transmembrane: {"description":"Helical; Name=5","evidences":[{"source":"PubMed","id":"18463093","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18480818","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21906602","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26024518","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	21
Details	Transmembrane: {"description":"Helical; Name=6","evidences":[{"source":"PubMed","id":"18463093","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18480818","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21906602","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26024518","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	21
Details	Transmembrane: {"description":"Helical; Name=7","evidences":[{"source":"PubMed","id":"18463093","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18480818","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21906602","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26024518","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	9
Details	Compositional bias: {"description":"Acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	1
Details	Modified residue: {"description":"N6-(retinylidene)lysine","evidences":[{"source":"PubMed","id":"18463093","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18480818","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21906602","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26024518","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"3191148","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2Z73","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4WW3","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	1
Details	Lipidation: {"description":"S-palmitoyl cysteine","evidences":[{"source":"PubMed","id":"18463093","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2ZIY","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	1
Details	Lipidation: {"description":"S-palmitoyl cysteine","evidences":[{"source":"PubMed","id":"18463093","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18480818","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2ZIY","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"18463093","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---