2ZE9

Crystal structure of H168A mutant of phospholipase D from Streptomyces antibioticus, as a complex with phosphatidylcholine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004630	molecular_function	phospholipase D activity
A	0005576	cellular_component	extracellular region
A	0006629	biological_process	lipid metabolic process
A	0006793	biological_process	phosphorus metabolic process
A	0016042	biological_process	lipid catabolic process
A	0016787	molecular_function	hydrolase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE MES A 510

Chain	Residue
A	HIS127
A	SER156
A	PRO231
A	ALA232
A	LYS233
A	TRP235
A	HOH691
A	HOH826
A	HOH869

---

site_id	AC2
Number of Residues	17
Details	BINDING SITE FOR RESIDUE PD7 A 511

Chain	Residue
A	LEU88
A	ALA123
A	TYR126
A	TRP166
A	ALA168
A	LYS170
A	ASN185
A	GLY381
A	HIS442
A	LYS444
A	ASN459
A	TYR461
A	ALA463
A	HOH600
A	HOH687
A	HOH763
A	HOH845

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	27
Details	Domain: {"description":"PLD phosphodiesterase 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00153","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	27
Details	Domain: {"description":"PLD phosphodiesterase 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00153","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	34
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

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