2ZCI

Structure of a GTP-dependent bacterial PEP-carboxykinase from Corynebacterium glutamicum

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004611	molecular_function	phosphoenolpyruvate carboxykinase activity
A	0004613	molecular_function	phosphoenolpyruvate carboxykinase (GTP) activity
A	0005525	molecular_function	GTP binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006094	biological_process	gluconeogenesis
A	0006107	biological_process	oxaloacetate metabolic process
A	0016829	molecular_function	lyase activity
A	0016831	molecular_function	carboxy-lyase activity
A	0017076	molecular_function	purine nucleotide binding
A	0019543	biological_process	propionate catabolic process
A	0030145	molecular_function	manganese ion binding
A	0033993	biological_process	response to lipid
A	0042594	biological_process	response to starvation
A	0046327	biological_process	glycerol biosynthetic process from pyruvate
A	0046872	molecular_function	metal ion binding
A	0071333	biological_process	cellular response to glucose stimulus
B	0000166	molecular_function	nucleotide binding
B	0004611	molecular_function	phosphoenolpyruvate carboxykinase activity
B	0004613	molecular_function	phosphoenolpyruvate carboxykinase (GTP) activity
B	0005525	molecular_function	GTP binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006094	biological_process	gluconeogenesis
B	0006107	biological_process	oxaloacetate metabolic process
B	0016829	molecular_function	lyase activity
B	0016831	molecular_function	carboxy-lyase activity
B	0017076	molecular_function	purine nucleotide binding
B	0019543	biological_process	propionate catabolic process
B	0030145	molecular_function	manganese ion binding
B	0033993	biological_process	response to lipid
B	0042594	biological_process	response to starvation
B	0046327	biological_process	glycerol biosynthetic process from pyruvate
B	0046872	molecular_function	metal ion binding
B	0071333	biological_process	cellular response to glucose stimulus
C	0000166	molecular_function	nucleotide binding
C	0004611	molecular_function	phosphoenolpyruvate carboxykinase activity
C	0004613	molecular_function	phosphoenolpyruvate carboxykinase (GTP) activity
C	0005525	molecular_function	GTP binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006094	biological_process	gluconeogenesis
C	0006107	biological_process	oxaloacetate metabolic process
C	0016829	molecular_function	lyase activity
C	0016831	molecular_function	carboxy-lyase activity
C	0017076	molecular_function	purine nucleotide binding
C	0019543	biological_process	propionate catabolic process
C	0030145	molecular_function	manganese ion binding
C	0033993	biological_process	response to lipid
C	0042594	biological_process	response to starvation
C	0046327	biological_process	glycerol biosynthetic process from pyruvate
C	0046872	molecular_function	metal ion binding
C	0071333	biological_process	cellular response to glucose stimulus
D	0000166	molecular_function	nucleotide binding
D	0004611	molecular_function	phosphoenolpyruvate carboxykinase activity
D	0004613	molecular_function	phosphoenolpyruvate carboxykinase (GTP) activity
D	0005525	molecular_function	GTP binding
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006094	biological_process	gluconeogenesis
D	0006107	biological_process	oxaloacetate metabolic process
D	0016829	molecular_function	lyase activity
D	0016831	molecular_function	carboxy-lyase activity
D	0017076	molecular_function	purine nucleotide binding
D	0019543	biological_process	propionate catabolic process
D	0030145	molecular_function	manganese ion binding
D	0033993	biological_process	response to lipid
D	0042594	biological_process	response to starvation
D	0046327	biological_process	glycerol biosynthetic process from pyruvate
D	0046872	molecular_function	metal ion binding
D	0071333	biological_process	cellular response to glucose stimulus

Functional Information from PROSITE/UniProt

site_id	PS00505
Number of Residues	9
Details	PEPCK_GTP Phosphoenolpyruvate carboxykinase (GTP) signature. FPSACGKTN

Chain	Residue	Details
A	PHE270-ASN278

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Active site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00452","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	76
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00452","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	3
Details	Annotated By Reference To The Literature 1aq2

Chain	Residue	Details
A	LYS276
A	ARG389
A	HIS250

---

site_id	CSA2
Number of Residues	3
Details	Annotated By Reference To The Literature 1aq2

Chain	Residue	Details
B	LYS276
B	ARG389
B	HIS250

---

site_id	CSA3
Number of Residues	3
Details	Annotated By Reference To The Literature 1aq2

Chain	Residue	Details
C	LYS276
C	ARG389
C	HIS250

---

site_id	CSA4
Number of Residues	3
Details	Annotated By Reference To The Literature 1aq2

Chain	Residue	Details
D	LYS276
D	ARG389
D	HIS250

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site_id	CSA5
Number of Residues	2
Details	Annotated By Reference To The Literature 1aq2

Chain	Residue	Details
A	ARG389
A	HIS250

---

site_id	CSA6
Number of Residues	2
Details	Annotated By Reference To The Literature 1aq2

Chain	Residue	Details
B	ARG389
B	HIS250

---

site_id	CSA7
Number of Residues	2
Details	Annotated By Reference To The Literature 1aq2

Chain	Residue	Details
C	ARG389
C	HIS250

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site_id	CSA8
Number of Residues	2
Details	Annotated By Reference To The Literature 1aq2

Chain	Residue	Details
D	ARG389
D	HIS250

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