Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003824 | molecular_function | catalytic activity |
A | 0005515 | molecular_function | protein binding |
A | 0005737 | cellular_component | cytoplasm |
A | 0006629 | biological_process | lipid metabolic process |
A | 0006693 | biological_process | prostaglandin metabolic process |
A | 0008270 | molecular_function | zinc ion binding |
A | 0016491 | molecular_function | oxidoreductase activity |
A | 0016628 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor |
A | 0047522 | molecular_function | 15-oxoprostaglandin 13-oxidase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE SO4 A 600 |
Chain | Residue |
A | THR189 |
A | HIS190 |
A | GLU191 |
A | ASN207 |
A | HOH1146 |
A | HOH1215 |
site_id | AC2 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE SO4 A 601 |
Chain | Residue |
A | ALA214 |
A | HOH1061 |
A | HOH1136 |
A | ASP211 |
A | ASN212 |
A | VAL213 |
site_id | AC3 |
Number of Residues | 37 |
Details | BINDING SITE FOR RESIDUE NAP A 700 |
Chain | Residue |
A | PRO50 |
A | MET135 |
A | THR139 |
A | GLY165 |
A | ALA166 |
A | CYS167 |
A | CYS187 |
A | GLY188 |
A | LYS192 |
A | TYR208 |
A | ASN231 |
A | VAL232 |
A | CYS253 |
A | GLY254 |
A | GLN255 |
A | ILE256 |
A | SER257 |
A | TYR259 |
A | PHE287 |
A | LEU288 |
A | VAL289 |
A | MET332 |
A | MET333 |
A | GLY335 |
A | ASN337 |
A | IMN800 |
A | HOH1016 |
A | HOH1019 |
A | HOH1038 |
A | HOH1039 |
A | HOH1042 |
A | HOH1043 |
A | HOH1044 |
A | HOH1045 |
A | HOH1110 |
A | HOH1224 |
A | HOH1388 |
site_id | AC4 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE IMN A 800 |
Chain | Residue |
A | TYR51 |
A | CYS54 |
A | THR60 |
A | TYR100 |
A | TYR259 |
A | LEU288 |
A | LEU290 |
A | NAP700 |
A | HOH1018 |
A | HOH1477 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 9 |
Details | BINDING: |
Chain | Residue | Details |
A | PHE99 | |
A | GLY165 | |
A | LYS192 | |
A | TYR208 | |
A | ASN231 | |
A | CYS253 | |
A | PHE287 | |
A | LEU288 | |
A | ASN337 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1guf |
Chain | Residue | Details |
A | THR60 | |