Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

2ZB3

Crystal structure of mouse 15-ketoprostaglandin delta-13-reductase in complex with NADPH

Functional Information from GO Data
ChainGOidnamespacecontents
A0005737cellular_componentcytoplasm
A0005739cellular_componentmitochondrion
A0005829cellular_componentcytosol
A0006629biological_processlipid metabolic process
A0006693biological_processprostaglandin metabolic process
A0008270molecular_functionzinc ion binding
A0016491molecular_functionoxidoreductase activity
A0016616molecular_functionoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
A0016628molecular_functionoxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
A0047522molecular_function15-oxoprostaglandin 13-oxidase [NAD(P)+] activity
Functional Information from PDB Data
site_idAC1
Number of Residues36
DetailsBINDING SITE FOR RESIDUE NDP A 900
ChainResidue
APRO50
ATYR208
AASN231
AVAL232
ACYS253
AGLY254
AGLN255
AILE256
ATYR259
APHE287
AVAL289
AMET135
AMET332
AMET333
AGLY335
AASN337
AGLY339
AHOH435
AHOH452
AHOH453
AHOH457
AHOH458
ATHR139
AHOH464
AHOH465
AHOH466
AHOH467
AHOH546
AHOH560
AHOH611
AGLY165
AALA166
ACYS167
ACYS187
AGLY188
ALYS192

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsBINDING: BINDING => ECO:0000250
ChainResidueDetails
APHE99
ATHR288

site_idSWS_FT_FI2
Number of Residues7
DetailsBINDING: BINDING => ECO:0000269|PubMed:19000823
ChainResidueDetails
AGLY165
ALYS192
ATYR208
AASN231
ACYS253
APHE287
AASN337

225946

PDB entries from 2024-10-09

PDB statisticsPDBj update infoContact PDBjnumon