2Z5F

Human sulfotransferase Sult1b1 in complex with PAP

Replaces:  1XV1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004062	molecular_function	aryl sulfotransferase activity
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006068	biological_process	ethanol catabolic process
A	0006576	biological_process	biogenic amine metabolic process
A	0006805	biological_process	xenobiotic metabolic process
A	0008146	molecular_function	sulfotransferase activity
A	0009812	biological_process	flavonoid metabolic process
A	0016740	molecular_function	transferase activity
A	0018958	biological_process	phenol-containing compound metabolic process
A	0030855	biological_process	epithelial cell differentiation
A	0042403	biological_process	thyroid hormone metabolic process
A	0050427	biological_process	3'-phosphoadenosine 5'-phosphosulfate metabolic process
A	0051923	biological_process	sulfation
B	0004062	molecular_function	aryl sulfotransferase activity
B	0005515	molecular_function	protein binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006068	biological_process	ethanol catabolic process
B	0006576	biological_process	biogenic amine metabolic process
B	0006805	biological_process	xenobiotic metabolic process
B	0008146	molecular_function	sulfotransferase activity
B	0009812	biological_process	flavonoid metabolic process
B	0016740	molecular_function	transferase activity
B	0018958	biological_process	phenol-containing compound metabolic process
B	0030855	biological_process	epithelial cell differentiation
B	0042403	biological_process	thyroid hormone metabolic process
B	0050427	biological_process	3'-phosphoadenosine 5'-phosphosulfate metabolic process
B	0051923	biological_process	sulfation

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Proton acceptor => ECO:0000250

Chain	Residue	Details
A	HIS109
B	HIS109

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site_id	SWS_FT_FI2
Number of Residues	12
Details	BINDING: BINDING => ECO:0000269|PubMed:16804942, ECO:0000269|Ref.8, ECO:0007744|PDB:2Z5F, ECO:0007744|PDB:3CKL

Chain	Residue	Details
A	LYS48
B	TYR194
B	THR228
B	ARG258
A	ARG131
A	SER139
A	TYR194
A	THR228
A	ARG258
B	LYS48
B	ARG131
B	SER139

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site_id	SWS_FT_FI3
Number of Residues	2
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	LYS107
B	LYS107

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