2Z4S

Crystal structure of domain III from the Thermotoga maritima replication initiation protein DnaA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003677	molecular_function	DNA binding
A	0003688	molecular_function	DNA replication origin binding
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005886	cellular_component	plasma membrane
A	0006260	biological_process	DNA replication
A	0006270	biological_process	DNA replication initiation
A	0006275	biological_process	regulation of DNA replication
A	0008289	molecular_function	lipid binding
A	0043565	molecular_function	sequence-specific DNA binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG A 500

Chain	Residue
A	THR144
A	ASP201
A	ASP202
A	ADP501

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site_id	AC2
Number of Residues	16
Details	BINDING SITE FOR RESIDUE ADP A 501

Chain	Residue
A	GLY138
A	VAL139
A	GLY140
A	LEU141
A	GLY142
A	LYS143
A	THR144
A	HIS145
A	ILE271
A	LEU299
A	MG500
A	TYR102
A	ASN106
A	PHE107
A	VAL108
A	ASN113

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Functional Information from PROSITE/UniProt

site_id	PS01008
Number of Residues	19
Details	DNAA DnaA protein signature. IAekFN.RsHPVVvdSvkkV

Chain	Residue	Details
A	ILE393-VAL411

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	216
Details	Region: {"description":"Domain III, AAA+ region","evidences":[{"source":"HAMAP-Rule","id":"MF_00377","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	5
Details	Binding site: {"evidences":[{"source":"PDB","id":"2Z4R","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2Z4S","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00377","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PDB","id":"2Z4R","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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