2Z0D
The crystal structure of human Atg4B- LC3(1-120) complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000045 | biological_process | autophagosome assembly |
| A | 0000421 | cellular_component | autophagosome membrane |
| A | 0000423 | biological_process | mitophagy |
| A | 0004175 | molecular_function | endopeptidase activity |
| A | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005776 | cellular_component | autophagosome |
| A | 0005783 | cellular_component | endoplasmic reticulum |
| A | 0005829 | cellular_component | cytosol |
| A | 0006508 | biological_process | proteolysis |
| A | 0006914 | biological_process | autophagy |
| A | 0008233 | molecular_function | peptidase activity |
| A | 0008234 | molecular_function | cysteine-type peptidase activity |
| A | 0015031 | biological_process | protein transport |
| A | 0016236 | biological_process | macroautophagy |
| A | 0016237 | biological_process | microautophagy |
| A | 0016485 | biological_process | protein processing |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0019786 | molecular_function | protein-phosphatidylethanolamide deconjugating activity |
| A | 0031173 | biological_process | otolith mineralization completed early in development |
| A | 0031410 | cellular_component | cytoplasmic vesicle |
| A | 0034497 | biological_process | protein localization to phagophore assembly site |
| A | 0034727 | biological_process | piecemeal microautophagy of the nucleus |
| A | 0035973 | biological_process | aggrephagy |
| A | 0051697 | biological_process | protein delipidation |
| A | 0097110 | molecular_function | scaffold protein binding |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"15169837","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15187094","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16183633","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16325851","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20818167","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26378241","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28821708","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30443548","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"evidences":[{"evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16183633","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16325851","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"16183633","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16325851","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine; by PKB/AKT1 and PKB/AKT2","evidences":[{"source":"PubMed","id":"29165041","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30443548","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"33607258","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"S-nitrosocysteine","evidences":[{"source":"PubMed","id":"28633005","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine; by ULK1","evidences":[{"source":"PubMed","id":"28821708","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Lipidation: {"description":"Phosphatidylserine amidated glycine; alternate","evidences":[{"source":"UniProtKB","id":"Q9GZQ8","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
