Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004639 | molecular_function | phosphoribosylaminoimidazolesuccinocarboxamide synthase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0006164 | biological_process | purine nucleotide biosynthetic process |
| A | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
| A | 0009236 | biological_process | cobalamin biosynthetic process |
| A | 0016874 | molecular_function | ligase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 511 |
| Chain | Residue |
| A | ASN139 |
| A | ASN139 |
| A | GLU140 |
| A | GLU140 |
| A | HOH529 |
| A | HOH618 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 512 |
| Chain | Residue |
| A | ARG206 |
| A | HOH538 |
| A | HOH604 |
| A | ILE98 |
| A | ARG100 |
| A | SER106 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE ADP A 500 |
| Chain | Residue |
| A | TYR15 |
| A | GLY17 |
| A | LYS18 |
| A | ALA19 |
| A | LYS20 |
| A | ILE22 |
| A | HIS75 |
| A | LYS88 |
| A | VAL90 |
| A | ILE92 |
| A | LYS129 |
| A | GLU185 |
| A | ASP198 |
| A | HOH593 |
| A | HOH602 |
| A | HOH615 |
Functional Information from PROSITE/UniProt
| site_id | PS01057 |
| Number of Residues | 15 |
| Details | SAICAR_SYNTHETASE_1 SAICAR synthetase signature 1. IIPIEvIVRniaAGS |
| Chain | Residue | Details |
| A | ILE92-SER106 | |
| site_id | PS01058 |
| Number of Residues | 9 |
| Details | SAICAR_SYNTHETASE_2 SAICAR synthetase signature 2. LVDfKIEIG |
| Chain | Residue | Details |
| A | LEU179-GLY187 | |
