2YWL
Crystal structure of thioredoxin reductase-related protein TTHA0370 from Thermus thermophilus HB8
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004791 | molecular_function | thioredoxin-disulfide reductase (NADPH) activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0045454 | biological_process | cell redox homeostasis |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004791 | molecular_function | thioredoxin-disulfide reductase (NADPH) activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0045454 | biological_process | cell redox homeostasis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 35 |
| Details | BINDING SITE FOR RESIDUE FAD A 1001 |
| Chain | Residue |
| A | GLY8 |
| A | LYS36 |
| A | VAL37 |
| A | VAL40 |
| A | ASN45 |
| A | GLY76 |
| A | VAL77 |
| A | VAL78 |
| A | CYS105 |
| A | THR106 |
| A | HIS107 |
| A | GLY10 |
| A | LEU112 |
| A | VAL143 |
| A | GLY150 |
| A | HIS151 |
| A | ALA152 |
| A | SER155 |
| A | HOH1002 |
| A | HOH1005 |
| A | HOH1008 |
| A | HOH1015 |
| A | PRO11 |
| A | HOH1017 |
| A | HOH1094 |
| A | HOH1095 |
| B | ASP177 |
| B | HIS178 |
| B | ALA179 |
| A | SER12 |
| A | ASP31 |
| A | GLY32 |
| A | GLY33 |
| A | ARG34 |
| A | SER35 |
| site_id | AC2 |
| Number of Residues | 37 |
| Details | BINDING SITE FOR RESIDUE FAD B 1002 |
| Chain | Residue |
| A | ASP177 |
| A | HIS178 |
| A | ALA179 |
| B | VAL7 |
| B | GLY8 |
| B | GLY10 |
| B | PRO11 |
| B | SER12 |
| B | LEU30 |
| B | ASP31 |
| B | GLY32 |
| B | GLY33 |
| B | ARG34 |
| B | SER35 |
| B | LYS36 |
| B | VAL37 |
| B | VAL40 |
| B | ASN45 |
| B | GLY76 |
| B | VAL77 |
| B | VAL78 |
| B | CYS105 |
| B | THR106 |
| B | HIS107 |
| B | LEU112 |
| B | VAL143 |
| B | GLY150 |
| B | HIS151 |
| B | ALA152 |
| B | SER155 |
| B | HOH1004 |
| B | HOH1005 |
| B | HOH1009 |
| B | HOH1023 |
| B | HOH1025 |
| B | HOH1029 |
| B | HOH1092 |
