2YVW

Crystal structure of UDP-N-acetylglucosamine 1-carboxyvinyltransferase from Aquifex aeolicus VF5

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0005737	cellular_component	cytoplasm
A	0008360	biological_process	regulation of cell shape
A	0008760	molecular_function	UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity
A	0009252	biological_process	peptidoglycan biosynthetic process
A	0016740	molecular_function	transferase activity
A	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
A	0019277	biological_process	UDP-N-acetylgalactosamine biosynthetic process
A	0051301	biological_process	cell division
A	0071555	biological_process	cell wall organization

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PO4 A 511

Chain	Residue
A	ARG98
A	MET99
A	ARG100
A	ARG403
A	HOH649
A	HOH705

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site_id	AC2
Number of Residues	32
Details	BINDING SITE FOR RESIDUE EPU A 501

Chain	Residue
A	ARG129
A	PRO130
A	ILE131
A	ASP132
A	GLN133
A	LEU168
A	VAL169
A	THR170
A	VAL171
A	THR172
A	ASP311
A	ILE333
A	PHE334
A	VAL353
A	LEU376
A	HOH605
A	HOH610
A	HOH616
A	HOH625
A	HOH629
A	HOH634
A	HOH636
A	HOH639
A	HOH641
A	HOH642
A	HOH649
A	HOH806
A	HOH807
A	HOH809
A	LYS31
A	ASN32
A	ALA101

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton donor => ECO:0000255|HAMAP-Rule:MF_00111, ECO:0000305|PubMed:22378791

Chain	Residue	Details
A	CYS124

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site_id	SWS_FT_FI2
Number of Residues	1
Details	BINDING: BINDING => ECO:0000305|PubMed:22378791, ECO:0007744|PDB:2YVW, ECO:0007744|PDB:3SWG

Chain	Residue	Details
A	LYS31

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site_id	SWS_FT_FI3
Number of Residues	1
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00111

Chain	Residue	Details
A	ARG100

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site_id	SWS_FT_FI4
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:22378791, ECO:0007744|PDB:2YVW, ECO:0007744|PDB:3SWG

Chain	Residue	Details
A	ARG129
A	THR170
A	ASP311
A	ILE333

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site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: 2-(S-cysteinyl)pyruvic acid O-phosphothioketal => ECO:0000255|HAMAP-Rule:MF_00111, ECO:0000305|PubMed:22378791

Chain	Residue	Details
A	CYS124

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	4
Details	Annotated By Reference To The Literature 1uae

Chain	Residue	Details
A	ASP311
A	ARG403
A	ASN32
A	CYS124

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