2YTZ
Complex structure of Trm1 from Pyrococcus horikoshii with S-adenosyl-L-Homocystein in the orthorhombic crystal-lattice
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000049 | molecular_function | tRNA binding |
| A | 0002940 | biological_process | tRNA N2-guanine methylation |
| A | 0003723 | molecular_function | RNA binding |
| A | 0008033 | biological_process | tRNA processing |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0016423 | molecular_function | tRNA (guanine) methyltransferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0030488 | biological_process | tRNA methylation |
| A | 0032259 | biological_process | methylation |
| A | 0160104 | molecular_function | tRNA (guanine(26)-N2)-dimethyltransferase activity |
| B | 0000049 | molecular_function | tRNA binding |
| B | 0002940 | biological_process | tRNA N2-guanine methylation |
| B | 0003723 | molecular_function | RNA binding |
| B | 0008033 | biological_process | tRNA processing |
| B | 0008168 | molecular_function | methyltransferase activity |
| B | 0016423 | molecular_function | tRNA (guanine) methyltransferase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0030488 | biological_process | tRNA methylation |
| B | 0032259 | biological_process | methylation |
| B | 0160104 | molecular_function | tRNA (guanine(26)-N2)-dimethyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1004 |
| Chain | Residue |
| A | HIS129 |
| A | ARG130 |
| A | ARG156 |
| B | HOH1071 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1005 |
| Chain | Residue |
| A | HIS174 |
| A | PRO175 |
| A | ARG176 |
| A | ALA177 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1007 |
| Chain | Residue |
| A | VAL338 |
| A | GLU339 |
| A | ARG354 |
| A | HOH1162 |
| A | LYS337 |
| site_id | AC4 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE SAH A 1001 |
| Chain | Residue |
| A | ARG36 |
| A | LEU55 |
| A | ALA57 |
| A | ILE60 |
| A | ARG61 |
| A | ASN77 |
| A | ASP78 |
| A | ILE79 |
| A | SER80 |
| A | ASP119 |
| A | ASP120 |
| A | ALA121 |
| A | ASP138 |
| A | PHE140 |
| A | PHE146 |
| A | GLN348 |
| A | HOH1009 |
| A | HOH1012 |
| A | HOH1030 |
| A | HOH1043 |
| A | HOH1095 |
| A | HOH1100 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1003 |
| Chain | Residue |
| B | HIS174 |
| B | PRO175 |
| B | ARG176 |
| B | ALA177 |
| B | HOH1046 |
| site_id | AC6 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE SAH B 1002 |
| Chain | Residue |
| B | PHE27 |
| B | ARG36 |
| B | LEU55 |
| B | ALA57 |
| B | ILE60 |
| B | ARG61 |
| B | ASP78 |
| B | ILE79 |
| B | SER80 |
| B | ASP119 |
| B | ASP120 |
| B | ALA121 |
| B | ASP138 |
| B | PHE140 |
| B | PHE146 |
| B | HOH1013 |
| B | HOH1030 |
| B | HOH1037 |
| B | HOH1116 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00290","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
