2YT4

Crystal structure of human DGCR8 core

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0020037	molecular_function	heme binding
A	0031053	biological_process	primary miRNA processing
A	0042802	molecular_function	identical protein binding
A	0070877	cellular_component	microprocessor complex

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	67
Details	Domain: {"description":"DRBM 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00266","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine; by ATM","evidences":[{"source":"PubMed","id":"34188037","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	2
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"PubMed","id":"25755297","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"28112733","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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