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2YS6

Crystal structure of GAR synthetase from Geobacillus kaustophilus

Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0003824molecular_functioncatalytic activity
A0004637molecular_functionphosphoribosylamine-glycine ligase activity
A0005524molecular_functionATP binding
A0006164biological_processpurine nucleotide biosynthetic process
A0006189biological_process'de novo' IMP biosynthetic process
A0009113biological_processpurine nucleobase biosynthetic process
A0016874molecular_functionligase activity
A0046872molecular_functionmetal ion binding
Functional Information from PDB Data
site_idAC1
Number of Residues10
DetailsBINDING SITE FOR RESIDUE GLY A 431
ChainResidue
AASP212
AHOH480
ALYS214
AGLY226
ATYR269
AASN285
AARG287
AGLY289
AASP290
AGLU292

site_idAC2
Number of Residues6
DetailsBINDING SITE FOR RESIDUE AMP A 432
ChainResidue
ALYS143
AGLU192
ALYS214
AASN224
AMET273
AILE282

Functional Information from PROSITE/UniProt
site_idPS00184
Number of Residues8
DetailsGARS Phosphoribosylglycinamide synthetase signature. RFGDPEaQ
ChainResidueDetails
AARG287-GLN294

218853

PDB entries from 2024-04-24

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