2YQS

Crystal structure of uridine-diphospho-N-acetylglucosamine pyrophosphorylase from Candida albicans, in the product-binding form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003977	molecular_function	UDP-N-acetylglucosamine diphosphorylase activity
A	0005737	cellular_component	cytoplasm
A	0006048	biological_process	UDP-N-acetylglucosamine biosynthetic process
A	0016740	molecular_function	transferase activity
A	0016779	molecular_function	nucleotidyltransferase activity
A	0019276	biological_process	UDP-N-acetylgalactosamine metabolic process
A	0052630	molecular_function	UDP-N-acetylgalactosamine diphosphorylase activity
A	0070569	molecular_function	uridylyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 1101

Chain	Residue
A	GLY114
A	THR115
A	ARG116
A	LYS123
A	HOH1425

---

site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG A 1201

Chain	Residue
A	ASN74
A	THR77

---

site_id	AC3
Number of Residues	24
Details	BINDING SITE FOR RESIDUE UD1 A 1001

Chain	Residue
A	GLY112
A	ARG116
A	MET168
A	GLN199
A	PRO224
A	GLY226
A	ASN227
A	CYS255
A	VAL256
A	VAL293
A	GLY294
A	GLU309
A	TYR310
A	ASN335
A	VAL337
A	PHE393
A	PHE395
A	LYS421
A	HOH1310
A	HOH1394
A	HOH1396
A	HOH1478
A	MET109
A	GLY111

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL A 1302

Chain	Residue
A	GLN7
A	ILE10
A	LYS14
A	TYR25

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 1303

Chain	Residue
A	THR92
A	LEU96
A	TYR467
A	GLY468
A	GLU470
A	HOH1412

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Motif: {"description":"Substrate binding","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q9M9P3","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---