Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE IK2 A 1445 |
| Chain | Residue |
| A | ARG54 |
| A | GLY174 |
| A | GLU220 |
| A | ASP253 |
| A | VAL255 |
| A | MET256 |
| A | LYS280 |
| A | HOH2056 |
| A | HOH2115 |
| A | HOH2117 |
| A | HOH2237 |
| A | ILE56 |
| B | ALA312 |
| B | GLY313 |
| B | THR314 |
| A | TYR89 |
| A | SER144 |
| A | GLY145 |
| A | THR146 |
| A | ASN149 |
| A | TYR172 |
| A | HIS173 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 1446 |
| Chain | Residue |
| B | ASP33 |
| B | ASN34 |
| B | TYR82 |
| B | EDO1448 |
| site_id | AC3 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE IK2 B 1447 |
| Chain | Residue |
| A | ALA312 |
| A | GLY313 |
| A | THR314 |
| A | HOH2113 |
| A | HOH2114 |
| A | HOH2190 |
| B | ARG54 |
| B | ILE56 |
| B | SER144 |
| B | GLY145 |
| B | THR146 |
| B | ASN149 |
| B | TYR172 |
| B | HIS173 |
| B | GLY174 |
| B | GLU220 |
| B | ASP253 |
| B | VAL255 |
| B | MET256 |
| B | LYS280 |
| B | EDO1453 |
| B | HOH2057 |
| B | HOH2087 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 1448 |
| Chain | Residue |
| B | HIS80 |
| B | ALA81 |
| B | TYR82 |
| B | LEU403 |
| B | GLY406 |
| B | EDO1446 |
| B | HOH2029 |
| site_id | AC5 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE IK2 C 1445 |
| Chain | Residue |
| C | ARG54 |
| C | ILE56 |
| C | TYR89 |
| C | SER144 |
| C | GLY145 |
| C | THR146 |
| C | ASN149 |
| C | TYR172 |
| C | HIS173 |
| C | GLY174 |
| C | GLU220 |
| C | ASP253 |
| C | VAL255 |
| C | MET256 |
| C | LYS280 |
| C | ALA312 |
| C | GLY313 |
| C | THR314 |
| C | EDO1449 |
| C | HOH2094 |
| C | HOH2096 |
| C | HOH2097 |
| C | HOH2127 |
| C | HOH2223 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 1449 |
| Chain | Residue |
| B | PRO230 |
| B | GLU232 |
| B | ILE381 |
| B | HOH2134 |
| B | HOH2160 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO C 1446 |
| Chain | Residue |
| C | ALA81 |
| C | TYR82 |
| C | LEU403 |
| C | ARG404 |
| C | HOH2044 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO C 1447 |
| Chain | Residue |
| C | ALA180 |
| C | GLY226 |
| C | ALA384 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 1446 |
| Chain | Residue |
| A | HIS40 |
| A | ARG43 |
| A | HOH2238 |
| B | GLU120 |
| B | ALA123 |
| site_id | BC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 1450 |
| Chain | Residue |
| B | LEU113 |
| B | ASN114 |
| B | ASN318 |
| B | ILE319 |
| B | LEU320 |
| B | HOH2043 |
| A | GLY285 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO C 1448 |
| Chain | Residue |
| C | ILE56 |
| C | TYR172 |
| C | ALA225 |
| C | EDO1449 |
| C | HOH2112 |
| site_id | BC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO C 1449 |
| Chain | Residue |
| C | ILE56 |
| C | TYR89 |
| C | ALA225 |
| C | MET256 |
| C | LYS280 |
| C | IK21445 |
| C | EDO1448 |
| site_id | BC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 1447 |
| Chain | Residue |
| A | LEU124 |
| A | GLU127 |
| A | ALA128 |
| A | HIS326 |
| A | HOH2101 |
| A | HOH2193 |
| C | ARG43 |
| C | GLU120 |
| site_id | BC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 1451 |
| Chain | Residue |
| A | GLU127 |
| A | CYS130 |
| A | HOH2100 |
| A | HOH2109 |
| B | ARG46 |
| B | HOH2161 |
| C | ARG43 |
| site_id | BC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO C 1450 |
| Chain | Residue |
| A | THR330 |
| A | HOH2193 |
| A | HOH2195 |
| C | ALA67 |
| C | VAL77 |
| C | GLU120 |
| C | HOH2224 |
| site_id | BC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 1448 |
| Chain | Residue |
| A | PRO221 |
| A | PRO230 |
| A | ALA231 |
| A | LEU236 |
| A | LEU269 |
| A | LEU368 |
| site_id | BC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO C 1451 |
| Chain | Residue |
| A | HOH2093 |
| B | ALA67 |
| C | HIS326 |
| C | THR330 |
| C | GLN331 |
| site_id | BC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO C 1452 |
| Chain | Residue |
| C | PRO221 |
| C | PRO230 |
| C | ALA231 |
| C | LEU236 |
| C | LEU269 |
| site_id | CC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE EDO A 1449 |
| Chain | Residue |
| A | ASN84 |
| A | GLY87 |
| A | GLU88 |
| A | GLY92 |
| A | GLY95 |
| A | HIS96 |
| A | SER418 |
| A | HOH2052 |
| B | ASN114 |
| B | SER116 |
| site_id | CC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 1452 |
| Chain | Residue |
| B | ALA180 |
| B | GLY226 |
| B | ALA384 |
| B | HOH2071 |
| site_id | CC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 1453 |
| Chain | Residue |
| B | ILE56 |
| B | TYR89 |
| B | ALA225 |
| B | MET256 |
| B | LYS280 |
| B | IK21447 |
| site_id | CC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO C 1453 |
| Chain | Residue |
| C | ASN198 |
| C | ASP199 |
| C | ARG382 |
| C | HOH2120 |
| C | HOH2122 |
| site_id | CC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 1450 |
| Chain | Residue |
| A | ASP33 |
| A | ASN34 |
| A | TYR82 |
| A | HOH2228 |
