2YIU

X-ray structure of the dimeric cytochrome BC1 complex from the soil bacterium paracoccus denitrificans at 2.7 angstrom resolution

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005886	cellular_component	plasma membrane
A	0008121	molecular_function	quinol-cytochrome-c reductase activity
A	0009055	molecular_function	electron transfer activity
A	0016020	cellular_component	membrane
A	0016491	molecular_function	oxidoreductase activity
A	0022904	biological_process	respiratory electron transport chain
A	0045275	cellular_component	respiratory chain complex III
A	0046872	molecular_function	metal ion binding
A	1902600	biological_process	proton transmembrane transport
B	0009055	molecular_function	electron transfer activity
B	0020037	molecular_function	heme binding
C	0005886	cellular_component	plasma membrane
C	0008121	molecular_function	quinol-cytochrome-c reductase activity
C	0016020	cellular_component	membrane
C	0046872	molecular_function	metal ion binding
C	0051536	molecular_function	iron-sulfur cluster binding
C	0051537	molecular_function	2 iron, 2 sulfur cluster binding
C	1902600	biological_process	proton transmembrane transport
D	0005886	cellular_component	plasma membrane
D	0008121	molecular_function	quinol-cytochrome-c reductase activity
D	0009055	molecular_function	electron transfer activity
D	0016020	cellular_component	membrane
D	0016491	molecular_function	oxidoreductase activity
D	0022904	biological_process	respiratory electron transport chain
D	0045275	cellular_component	respiratory chain complex III
D	0046872	molecular_function	metal ion binding
D	1902600	biological_process	proton transmembrane transport
E	0009055	molecular_function	electron transfer activity
E	0020037	molecular_function	heme binding
F	0005886	cellular_component	plasma membrane
F	0008121	molecular_function	quinol-cytochrome-c reductase activity
F	0016020	cellular_component	membrane
F	0046872	molecular_function	metal ion binding
F	0051536	molecular_function	iron-sulfur cluster binding
F	0051537	molecular_function	2 iron, 2 sulfur cluster binding
F	1902600	biological_process	proton transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	BINDING SITE FOR RESIDUE HEM A 500

Chain	Residue
A	GLN58
A	LEU149
A	PRO150
A	HIS198
A	PRO202
A	GLY62
A	ILE63
A	VAL66
A	ARG94
A	HIS97
A	PHE104
A	THR142
A	GLY146

---

site_id	AC2
Number of Residues	18
Details	BINDING SITE FOR RESIDUE HEM A 501

Chain	Residue
A	TRP45
A	GLY48
A	LEU51
A	ALA52
A	HIS111
A	ARG114
A	SER120
A	ARG125
A	TRP129
A	GLY132
A	MET133
A	ILE135
A	HIS212
A	PHE216
A	GLY220
A	ASN221
A	ASN222
A	HOH2002

---

site_id	AC3
Number of Residues	13
Details	BINDING SITE FOR RESIDUE SMA A 502

Chain	Residue
A	LEU137
A	MET154
A	GLY158
A	VAL161
A	PHE194
A	ILE292
A	GLU295
A	PHE298
A	TYR302
A	MET336
A	PHE337
F	CYS154
F	HIS155

---

site_id	AC4
Number of Residues	11
Details	BINDING SITE FOR RESIDUE HEC B 500

Chain	Residue
B	VAL81
B	CYS82
B	CYS85
B	HIS86
B	PRO145
B	ARG154
B	TYR177
B	LEU182
B	PHE203
B	GLN209
B	MET210

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FES C 500

Chain	Residue
C	CYS132
C	HIS134
C	LEU135
C	CYS152
C	HIS155
C	SER157

---

site_id	AC6
Number of Residues	13
Details	BINDING SITE FOR RESIDUE HEM D 500

Chain	Residue
D	GLN58
D	GLY62
D	ILE63
D	VAL66
D	ARG94
D	HIS97
D	ALA98
D	PHE104
D	GLY146
D	LEU149
D	PRO150
D	HIS198
D	PRO202

---

site_id	AC7
Number of Residues	17
Details	BINDING SITE FOR RESIDUE HEM D 501

Chain	Residue
D	TRP45
D	GLY48
D	LEU51
D	ALA52
D	HIS111
D	ARG114
D	SER120
D	ARG125
D	GLY132
D	MET133
D	ILE135
D	VAL209
D	HIS212
D	PHE216
D	GLY220
D	ASN221
D	ASN222

---

site_id	AC8
Number of Residues	13
Details	BINDING SITE FOR RESIDUE SMA D 502

Chain	Residue
D	PHE298
D	TYR302
D	MET336
D	PHE337
D	ILE340
C	CYS154
C	HIS155
D	LEU137
D	MET140
D	VAL161
D	ILE292
D	PRO294
D	GLU295

---

site_id	AC9
Number of Residues	10
Details	BINDING SITE FOR RESIDUE HEC E 500

Chain	Residue
E	VAL81
E	CYS82
E	CYS85
E	HIS86
E	ARG154
E	TYR177
E	PHE203
E	GLN209
E	MET210
E	PRO213

---

site_id	BC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE FES F 500

Chain	Residue
F	CYS132
F	HIS134
F	LEU135
F	CYS152
F	HIS155
F	SER157

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	440
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	10
Details	Binding site: {"description":"axial binding residue"}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	28
Details	Transmembrane: {"description":"Helical; Note=Anchors to the membrane","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	42
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	Binding site: {"description":"covalent"}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	Binding site: {"description":"axial binding residue","evidences":[{"source":"PROSITE-ProRule","id":"PRU00433","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	186
Details	Domain: {"description":"Rieske","evidences":[{"source":"PROSITE-ProRule","id":"PRU00628","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00628","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---