2YGD

Molecular architectures of the 24meric eye lens chaperone alphaB- crystallin elucidated by a triple hybrid approach

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001540	molecular_function	amyloid-beta binding
A	0005198	molecular_function	structural molecule activity
A	0005212	molecular_function	structural constituent of eye lens
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0005739	cellular_component	mitochondrion
A	0005764	cellular_component	lysosome
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0006457	biological_process	protein folding
A	0006936	biological_process	muscle contraction
A	0008017	molecular_function	microtubule binding
A	0008092	molecular_function	cytoskeletal protein binding
A	0009408	biological_process	response to heat
A	0009892	biological_process	negative regulation of metabolic process
A	0009986	cellular_component	cell surface
A	0030018	cellular_component	Z disc
A	0030308	biological_process	negative regulation of cell growth
A	0030424	cellular_component	axon
A	0031109	biological_process	microtubule polymerization or depolymerization
A	0031333	biological_process	negative regulation of protein-containing complex assembly
A	0031430	cellular_component	M band
A	0031674	cellular_component	I band
A	0032355	biological_process	response to estradiol
A	0032387	biological_process	negative regulation of intracellular transport
A	0032432	cellular_component	actin filament bundle
A	0032991	cellular_component	protein-containing complex
A	0042026	biological_process	protein refolding
A	0042542	biological_process	response to hydrogen peroxide
A	0042802	molecular_function	identical protein binding
A	0042803	molecular_function	protein homodimerization activity
A	0043066	biological_process	negative regulation of apoptotic process
A	0043067	biological_process	regulation of programmed cell death
A	0043197	cellular_component	dendritic spine
A	0043204	cellular_component	perikaryon
A	0043292	cellular_component	contractile muscle fiber
A	0044877	molecular_function	protein-containing complex binding
A	0045892	biological_process	negative regulation of DNA-templated transcription
A	0046872	molecular_function	metal ion binding
A	0050821	biological_process	protein stabilization
A	0051082	molecular_function	unfolded protein binding
A	0051403	biological_process	stress-activated MAPK cascade
A	0070062	cellular_component	extracellular exosome
A	0071480	biological_process	cellular response to gamma radiation
A	0097060	cellular_component	synaptic membrane
A	0097512	cellular_component	cardiac myofibril
A	1905907	biological_process	negative regulation of amyloid fibril formation
A	2000378	biological_process	negative regulation of reactive oxygen species metabolic process
B	0001540	molecular_function	amyloid-beta binding
B	0005198	molecular_function	structural molecule activity
B	0005212	molecular_function	structural constituent of eye lens
B	0005515	molecular_function	protein binding
B	0005576	cellular_component	extracellular region
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005737	cellular_component	cytoplasm
B	0005739	cellular_component	mitochondrion
B	0005764	cellular_component	lysosome
B	0005829	cellular_component	cytosol
B	0005886	cellular_component	plasma membrane
B	0006457	biological_process	protein folding
B	0006936	biological_process	muscle contraction
B	0008017	molecular_function	microtubule binding
B	0008092	molecular_function	cytoskeletal protein binding
B	0009408	biological_process	response to heat
B	0009892	biological_process	negative regulation of metabolic process
B	0009986	cellular_component	cell surface
B	0030018	cellular_component	Z disc
B	0030308	biological_process	negative regulation of cell growth
B	0030424	cellular_component	axon
B	0031109	biological_process	microtubule polymerization or depolymerization
B	0031333	biological_process	negative regulation of protein-containing complex assembly
B	0031430	cellular_component	M band
B	0031674	cellular_component	I band
B	0032355	biological_process	response to estradiol
B	0032387	biological_process	negative regulation of intracellular transport
B	0032432	cellular_component	actin filament bundle
B	0032991	cellular_component	protein-containing complex
B	0042026	biological_process	protein refolding
B	0042542	biological_process	response to hydrogen peroxide
B	0042802	molecular_function	identical protein binding
B	0042803	molecular_function	protein homodimerization activity
B	0043066	biological_process	negative regulation of apoptotic process
B	0043067	biological_process	regulation of programmed cell death
B	0043197	cellular_component	dendritic spine
B	0043204	cellular_component	perikaryon
B	0043292	cellular_component	contractile muscle fiber
B	0044877	molecular_function	protein-containing complex binding
B	0045892	biological_process	negative regulation of DNA-templated transcription
B	0046872	molecular_function	metal ion binding
B	0050821	biological_process	protein stabilization
B	0051082	molecular_function	unfolded protein binding
B	0051403	biological_process	stress-activated MAPK cascade
B	0070062	cellular_component	extracellular exosome
B	0071480	biological_process	cellular response to gamma radiation
B	0097060	cellular_component	synaptic membrane
B	0097512	cellular_component	cardiac myofibril
B	1905907	biological_process	negative regulation of amyloid fibril formation
B	2000378	biological_process	negative regulation of reactive oxygen species metabolic process
C	0001540	molecular_function	amyloid-beta binding
C	0005198	molecular_function	structural molecule activity
C	0005212	molecular_function	structural constituent of eye lens
C	0005515	molecular_function	protein binding
C	0005576	cellular_component	extracellular region
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005737	cellular_component	cytoplasm
C	0005739	cellular_component	mitochondrion
C	0005764	cellular_component	lysosome
C	0005829	cellular_component	cytosol
C	0005886	cellular_component	plasma membrane
C	0006457	biological_process	protein folding
C	0006936	biological_process	muscle contraction
C	0008017	molecular_function	microtubule binding
C	0008092	molecular_function	cytoskeletal protein binding
C	0009408	biological_process	response to heat
C	0009892	biological_process	negative regulation of metabolic process
C	0009986	cellular_component	cell surface
C	0030018	cellular_component	Z disc
C	0030308	biological_process	negative regulation of cell growth
C	0030424	cellular_component	axon
C	0031109	biological_process	microtubule polymerization or depolymerization
C	0031333	biological_process	negative regulation of protein-containing complex assembly
C	0031430	cellular_component	M band
C	0031674	cellular_component	I band
C	0032355	biological_process	response to estradiol
C	0032387	biological_process	negative regulation of intracellular transport
C	0032432	cellular_component	actin filament bundle
C	0032991	cellular_component	protein-containing complex
C	0042026	biological_process	protein refolding
C	0042542	biological_process	response to hydrogen peroxide
C	0042802	molecular_function	identical protein binding
C	0042803	molecular_function	protein homodimerization activity
C	0043066	biological_process	negative regulation of apoptotic process
C	0043067	biological_process	regulation of programmed cell death
C	0043197	cellular_component	dendritic spine
C	0043204	cellular_component	perikaryon
C	0043292	cellular_component	contractile muscle fiber
C	0044877	molecular_function	protein-containing complex binding
C	0045892	biological_process	negative regulation of DNA-templated transcription
C	0046872	molecular_function	metal ion binding
C	0050821	biological_process	protein stabilization
C	0051082	molecular_function	unfolded protein binding
C	0051403	biological_process	stress-activated MAPK cascade
C	0070062	cellular_component	extracellular exosome
C	0071480	biological_process	cellular response to gamma radiation
C	0097060	cellular_component	synaptic membrane
C	0097512	cellular_component	cardiac myofibril
C	1905907	biological_process	negative regulation of amyloid fibril formation
C	2000378	biological_process	negative regulation of reactive oxygen species metabolic process
D	0001540	molecular_function	amyloid-beta binding
D	0005198	molecular_function	structural molecule activity
D	0005212	molecular_function	structural constituent of eye lens
D	0005515	molecular_function	protein binding
D	0005576	cellular_component	extracellular region
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005737	cellular_component	cytoplasm
D	0005739	cellular_component	mitochondrion
D	0005764	cellular_component	lysosome
D	0005829	cellular_component	cytosol
D	0005886	cellular_component	plasma membrane
D	0006457	biological_process	protein folding
D	0006936	biological_process	muscle contraction
D	0008017	molecular_function	microtubule binding
D	0008092	molecular_function	cytoskeletal protein binding
D	0009408	biological_process	response to heat
D	0009892	biological_process	negative regulation of metabolic process
D	0009986	cellular_component	cell surface
D	0030018	cellular_component	Z disc
D	0030308	biological_process	negative regulation of cell growth
D	0030424	cellular_component	axon
D	0031109	biological_process	microtubule polymerization or depolymerization
D	0031333	biological_process	negative regulation of protein-containing complex assembly
D	0031430	cellular_component	M band
D	0031674	cellular_component	I band
D	0032355	biological_process	response to estradiol
D	0032387	biological_process	negative regulation of intracellular transport
D	0032432	cellular_component	actin filament bundle
D	0032991	cellular_component	protein-containing complex
D	0042026	biological_process	protein refolding
D	0042542	biological_process	response to hydrogen peroxide
D	0042802	molecular_function	identical protein binding
D	0042803	molecular_function	protein homodimerization activity
D	0043066	biological_process	negative regulation of apoptotic process
D	0043067	biological_process	regulation of programmed cell death
D	0043197	cellular_component	dendritic spine
D	0043204	cellular_component	perikaryon
D	0043292	cellular_component	contractile muscle fiber
D	0044877	molecular_function	protein-containing complex binding
D	0045892	biological_process	negative regulation of DNA-templated transcription
D	0046872	molecular_function	metal ion binding
D	0050821	biological_process	protein stabilization
D	0051082	molecular_function	unfolded protein binding
D	0051403	biological_process	stress-activated MAPK cascade
D	0070062	cellular_component	extracellular exosome
D	0071480	biological_process	cellular response to gamma radiation
D	0097060	cellular_component	synaptic membrane
D	0097512	cellular_component	cardiac myofibril
D	1905907	biological_process	negative regulation of amyloid fibril formation
D	2000378	biological_process	negative regulation of reactive oxygen species metabolic process
E	0001540	molecular_function	amyloid-beta binding
E	0005198	molecular_function	structural molecule activity
E	0005212	molecular_function	structural constituent of eye lens
E	0005515	molecular_function	protein binding
E	0005576	cellular_component	extracellular region
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005737	cellular_component	cytoplasm
E	0005739	cellular_component	mitochondrion
E	0005764	cellular_component	lysosome
E	0005829	cellular_component	cytosol
E	0005886	cellular_component	plasma membrane
E	0006457	biological_process	protein folding
E	0006936	biological_process	muscle contraction
E	0008017	molecular_function	microtubule binding
E	0008092	molecular_function	cytoskeletal protein binding
E	0009408	biological_process	response to heat
E	0009892	biological_process	negative regulation of metabolic process
E	0009986	cellular_component	cell surface
E	0030018	cellular_component	Z disc
E	0030308	biological_process	negative regulation of cell growth
E	0030424	cellular_component	axon
E	0031109	biological_process	microtubule polymerization or depolymerization
E	0031333	biological_process	negative regulation of protein-containing complex assembly
E	0031430	cellular_component	M band
E	0031674	cellular_component	I band
E	0032355	biological_process	response to estradiol
E	0032387	biological_process	negative regulation of intracellular transport
E	0032432	cellular_component	actin filament bundle
E	0032991	cellular_component	protein-containing complex
E	0042026	biological_process	protein refolding
E	0042542	biological_process	response to hydrogen peroxide
E	0042802	molecular_function	identical protein binding
E	0042803	molecular_function	protein homodimerization activity
E	0043066	biological_process	negative regulation of apoptotic process
E	0043067	biological_process	regulation of programmed cell death
E	0043197	cellular_component	dendritic spine
E	0043204	cellular_component	perikaryon
E	0043292	cellular_component	contractile muscle fiber
E	0044877	molecular_function	protein-containing complex binding
E	0045892	biological_process	negative regulation of DNA-templated transcription
E	0046872	molecular_function	metal ion binding
E	0050821	biological_process	protein stabilization
E	0051082	molecular_function	unfolded protein binding
E	0051403	biological_process	stress-activated MAPK cascade
E	0070062	cellular_component	extracellular exosome
E	0071480	biological_process	cellular response to gamma radiation
E	0097060	cellular_component	synaptic membrane
E	0097512	cellular_component	cardiac myofibril
E	1905907	biological_process	negative regulation of amyloid fibril formation
E	2000378	biological_process	negative regulation of reactive oxygen species metabolic process
F	0001540	molecular_function	amyloid-beta binding
F	0005198	molecular_function	structural molecule activity
F	0005212	molecular_function	structural constituent of eye lens
F	0005515	molecular_function	protein binding
F	0005576	cellular_component	extracellular region
F	0005634	cellular_component	nucleus
F	0005654	cellular_component	nucleoplasm
F	0005737	cellular_component	cytoplasm
F	0005739	cellular_component	mitochondrion
F	0005764	cellular_component	lysosome
F	0005829	cellular_component	cytosol
F	0005886	cellular_component	plasma membrane
F	0006457	biological_process	protein folding
F	0006936	biological_process	muscle contraction
F	0008017	molecular_function	microtubule binding
F	0008092	molecular_function	cytoskeletal protein binding
F	0009408	biological_process	response to heat
F	0009892	biological_process	negative regulation of metabolic process
F	0009986	cellular_component	cell surface
F	0030018	cellular_component	Z disc
F	0030308	biological_process	negative regulation of cell growth
F	0030424	cellular_component	axon
F	0031109	biological_process	microtubule polymerization or depolymerization
F	0031333	biological_process	negative regulation of protein-containing complex assembly
F	0031430	cellular_component	M band
F	0031674	cellular_component	I band
F	0032355	biological_process	response to estradiol
F	0032387	biological_process	negative regulation of intracellular transport
F	0032432	cellular_component	actin filament bundle
F	0032991	cellular_component	protein-containing complex
F	0042026	biological_process	protein refolding
F	0042542	biological_process	response to hydrogen peroxide
F	0042802	molecular_function	identical protein binding
F	0042803	molecular_function	protein homodimerization activity
F	0043066	biological_process	negative regulation of apoptotic process
F	0043067	biological_process	regulation of programmed cell death
F	0043197	cellular_component	dendritic spine
F	0043204	cellular_component	perikaryon
F	0043292	cellular_component	contractile muscle fiber
F	0044877	molecular_function	protein-containing complex binding
F	0045892	biological_process	negative regulation of DNA-templated transcription
F	0046872	molecular_function	metal ion binding
F	0050821	biological_process	protein stabilization
F	0051082	molecular_function	unfolded protein binding
F	0051403	biological_process	stress-activated MAPK cascade
F	0070062	cellular_component	extracellular exosome
F	0071480	biological_process	cellular response to gamma radiation
F	0097060	cellular_component	synaptic membrane
F	0097512	cellular_component	cardiac myofibril
F	1905907	biological_process	negative regulation of amyloid fibril formation
F	2000378	biological_process	negative regulation of reactive oxygen species metabolic process
G	0001540	molecular_function	amyloid-beta binding
G	0005198	molecular_function	structural molecule activity
G	0005212	molecular_function	structural constituent of eye lens
G	0005515	molecular_function	protein binding
G	0005576	cellular_component	extracellular region
G	0005634	cellular_component	nucleus
G	0005654	cellular_component	nucleoplasm
G	0005737	cellular_component	cytoplasm
G	0005739	cellular_component	mitochondrion
G	0005764	cellular_component	lysosome
G	0005829	cellular_component	cytosol
G	0005886	cellular_component	plasma membrane
G	0006457	biological_process	protein folding
G	0006936	biological_process	muscle contraction
G	0008017	molecular_function	microtubule binding
G	0008092	molecular_function	cytoskeletal protein binding
G	0009408	biological_process	response to heat
G	0009892	biological_process	negative regulation of metabolic process
G	0009986	cellular_component	cell surface
G	0030018	cellular_component	Z disc
G	0030308	biological_process	negative regulation of cell growth
G	0030424	cellular_component	axon
G	0031109	biological_process	microtubule polymerization or depolymerization
G	0031333	biological_process	negative regulation of protein-containing complex assembly
G	0031430	cellular_component	M band
G	0031674	cellular_component	I band
G	0032355	biological_process	response to estradiol
G	0032387	biological_process	negative regulation of intracellular transport
G	0032432	cellular_component	actin filament bundle
G	0032991	cellular_component	protein-containing complex
G	0042026	biological_process	protein refolding
G	0042542	biological_process	response to hydrogen peroxide
G	0042802	molecular_function	identical protein binding
G	0042803	molecular_function	protein homodimerization activity
G	0043066	biological_process	negative regulation of apoptotic process
G	0043067	biological_process	regulation of programmed cell death
G	0043197	cellular_component	dendritic spine
G	0043204	cellular_component	perikaryon
G	0043292	cellular_component	contractile muscle fiber
G	0044877	molecular_function	protein-containing complex binding
G	0045892	biological_process	negative regulation of DNA-templated transcription
G	0046872	molecular_function	metal ion binding
G	0050821	biological_process	protein stabilization
G	0051082	molecular_function	unfolded protein binding
G	0051403	biological_process	stress-activated MAPK cascade
G	0070062	cellular_component	extracellular exosome
G	0071480	biological_process	cellular response to gamma radiation
G	0097060	cellular_component	synaptic membrane
G	0097512	cellular_component	cardiac myofibril
G	1905907	biological_process	negative regulation of amyloid fibril formation
G	2000378	biological_process	negative regulation of reactive oxygen species metabolic process
H	0001540	molecular_function	amyloid-beta binding
H	0005198	molecular_function	structural molecule activity
H	0005212	molecular_function	structural constituent of eye lens
H	0005515	molecular_function	protein binding
H	0005576	cellular_component	extracellular region
H	0005634	cellular_component	nucleus
H	0005654	cellular_component	nucleoplasm
H	0005737	cellular_component	cytoplasm
H	0005739	cellular_component	mitochondrion
H	0005764	cellular_component	lysosome
H	0005829	cellular_component	cytosol
H	0005886	cellular_component	plasma membrane
H	0006457	biological_process	protein folding
H	0006936	biological_process	muscle contraction
H	0008017	molecular_function	microtubule binding
H	0008092	molecular_function	cytoskeletal protein binding
H	0009408	biological_process	response to heat
H	0009892	biological_process	negative regulation of metabolic process
H	0009986	cellular_component	cell surface
H	0030018	cellular_component	Z disc
H	0030308	biological_process	negative regulation of cell growth
H	0030424	cellular_component	axon
H	0031109	biological_process	microtubule polymerization or depolymerization
H	0031333	biological_process	negative regulation of protein-containing complex assembly
H	0031430	cellular_component	M band
H	0031674	cellular_component	I band
H	0032355	biological_process	response to estradiol
H	0032387	biological_process	negative regulation of intracellular transport
H	0032432	cellular_component	actin filament bundle
H	0032991	cellular_component	protein-containing complex
H	0042026	biological_process	protein refolding
H	0042542	biological_process	response to hydrogen peroxide
H	0042802	molecular_function	identical protein binding
H	0042803	molecular_function	protein homodimerization activity
H	0043066	biological_process	negative regulation of apoptotic process
H	0043067	biological_process	regulation of programmed cell death
H	0043197	cellular_component	dendritic spine
H	0043204	cellular_component	perikaryon
H	0043292	cellular_component	contractile muscle fiber
H	0044877	molecular_function	protein-containing complex binding
H	0045892	biological_process	negative regulation of DNA-templated transcription
H	0046872	molecular_function	metal ion binding
H	0050821	biological_process	protein stabilization
H	0051082	molecular_function	unfolded protein binding
H	0051403	biological_process	stress-activated MAPK cascade
H	0070062	cellular_component	extracellular exosome
H	0071480	biological_process	cellular response to gamma radiation
H	0097060	cellular_component	synaptic membrane
H	0097512	cellular_component	cardiac myofibril
H	1905907	biological_process	negative regulation of amyloid fibril formation
H	2000378	biological_process	negative regulation of reactive oxygen species metabolic process
I	0001540	molecular_function	amyloid-beta binding
I	0005198	molecular_function	structural molecule activity
I	0005212	molecular_function	structural constituent of eye lens
I	0005515	molecular_function	protein binding
I	0005576	cellular_component	extracellular region
I	0005634	cellular_component	nucleus
I	0005654	cellular_component	nucleoplasm
I	0005737	cellular_component	cytoplasm
I	0005739	cellular_component	mitochondrion
I	0005764	cellular_component	lysosome
I	0005829	cellular_component	cytosol
I	0005886	cellular_component	plasma membrane
I	0006457	biological_process	protein folding
I	0006936	biological_process	muscle contraction
I	0008017	molecular_function	microtubule binding
I	0008092	molecular_function	cytoskeletal protein binding
I	0009408	biological_process	response to heat
I	0009892	biological_process	negative regulation of metabolic process
I	0009986	cellular_component	cell surface
I	0030018	cellular_component	Z disc
I	0030308	biological_process	negative regulation of cell growth
I	0030424	cellular_component	axon
I	0031109	biological_process	microtubule polymerization or depolymerization
I	0031333	biological_process	negative regulation of protein-containing complex assembly
I	0031430	cellular_component	M band
I	0031674	cellular_component	I band
I	0032355	biological_process	response to estradiol
I	0032387	biological_process	negative regulation of intracellular transport
I	0032432	cellular_component	actin filament bundle
I	0032991	cellular_component	protein-containing complex
I	0042026	biological_process	protein refolding
I	0042542	biological_process	response to hydrogen peroxide
I	0042802	molecular_function	identical protein binding
I	0042803	molecular_function	protein homodimerization activity
I	0043066	biological_process	negative regulation of apoptotic process
I	0043067	biological_process	regulation of programmed cell death
I	0043197	cellular_component	dendritic spine
I	0043204	cellular_component	perikaryon
I	0043292	cellular_component	contractile muscle fiber
I	0044877	molecular_function	protein-containing complex binding
I	0045892	biological_process	negative regulation of DNA-templated transcription
I	0046872	molecular_function	metal ion binding
I	0050821	biological_process	protein stabilization
I	0051082	molecular_function	unfolded protein binding
I	0051403	biological_process	stress-activated MAPK cascade
I	0070062	cellular_component	extracellular exosome
I	0071480	biological_process	cellular response to gamma radiation
I	0097060	cellular_component	synaptic membrane
I	0097512	cellular_component	cardiac myofibril
I	1905907	biological_process	negative regulation of amyloid fibril formation
I	2000378	biological_process	negative regulation of reactive oxygen species metabolic process
J	0001540	molecular_function	amyloid-beta binding
J	0005198	molecular_function	structural molecule activity
J	0005212	molecular_function	structural constituent of eye lens
J	0005515	molecular_function	protein binding
J	0005576	cellular_component	extracellular region
J	0005634	cellular_component	nucleus
J	0005654	cellular_component	nucleoplasm
J	0005737	cellular_component	cytoplasm
J	0005739	cellular_component	mitochondrion
J	0005764	cellular_component	lysosome
J	0005829	cellular_component	cytosol
J	0005886	cellular_component	plasma membrane
J	0006457	biological_process	protein folding
J	0006936	biological_process	muscle contraction
J	0008017	molecular_function	microtubule binding
J	0008092	molecular_function	cytoskeletal protein binding
J	0009408	biological_process	response to heat
J	0009892	biological_process	negative regulation of metabolic process
J	0009986	cellular_component	cell surface
J	0030018	cellular_component	Z disc
J	0030308	biological_process	negative regulation of cell growth
J	0030424	cellular_component	axon
J	0031109	biological_process	microtubule polymerization or depolymerization
J	0031333	biological_process	negative regulation of protein-containing complex assembly
J	0031430	cellular_component	M band
J	0031674	cellular_component	I band
J	0032355	biological_process	response to estradiol
J	0032387	biological_process	negative regulation of intracellular transport
J	0032432	cellular_component	actin filament bundle
J	0032991	cellular_component	protein-containing complex
J	0042026	biological_process	protein refolding
J	0042542	biological_process	response to hydrogen peroxide
J	0042802	molecular_function	identical protein binding
J	0042803	molecular_function	protein homodimerization activity
J	0043066	biological_process	negative regulation of apoptotic process
J	0043067	biological_process	regulation of programmed cell death
J	0043197	cellular_component	dendritic spine
J	0043204	cellular_component	perikaryon
J	0043292	cellular_component	contractile muscle fiber
J	0044877	molecular_function	protein-containing complex binding
J	0045892	biological_process	negative regulation of DNA-templated transcription
J	0046872	molecular_function	metal ion binding
J	0050821	biological_process	protein stabilization
J	0051082	molecular_function	unfolded protein binding
J	0051403	biological_process	stress-activated MAPK cascade
J	0070062	cellular_component	extracellular exosome
J	0071480	biological_process	cellular response to gamma radiation
J	0097060	cellular_component	synaptic membrane
J	0097512	cellular_component	cardiac myofibril
J	1905907	biological_process	negative regulation of amyloid fibril formation
J	2000378	biological_process	negative regulation of reactive oxygen species metabolic process
K	0001540	molecular_function	amyloid-beta binding
K	0005198	molecular_function	structural molecule activity
K	0005212	molecular_function	structural constituent of eye lens
K	0005515	molecular_function	protein binding
K	0005576	cellular_component	extracellular region
K	0005634	cellular_component	nucleus
K	0005654	cellular_component	nucleoplasm
K	0005737	cellular_component	cytoplasm
K	0005739	cellular_component	mitochondrion
K	0005764	cellular_component	lysosome
K	0005829	cellular_component	cytosol
K	0005886	cellular_component	plasma membrane
K	0006457	biological_process	protein folding
K	0006936	biological_process	muscle contraction
K	0008017	molecular_function	microtubule binding
K	0008092	molecular_function	cytoskeletal protein binding
K	0009408	biological_process	response to heat
K	0009892	biological_process	negative regulation of metabolic process
K	0009986	cellular_component	cell surface
K	0030018	cellular_component	Z disc
K	0030308	biological_process	negative regulation of cell growth
K	0030424	cellular_component	axon
K	0031109	biological_process	microtubule polymerization or depolymerization
K	0031333	biological_process	negative regulation of protein-containing complex assembly
K	0031430	cellular_component	M band
K	0031674	cellular_component	I band
K	0032355	biological_process	response to estradiol
K	0032387	biological_process	negative regulation of intracellular transport
K	0032432	cellular_component	actin filament bundle
K	0032991	cellular_component	protein-containing complex
K	0042026	biological_process	protein refolding
K	0042542	biological_process	response to hydrogen peroxide
K	0042802	molecular_function	identical protein binding
K	0042803	molecular_function	protein homodimerization activity
K	0043066	biological_process	negative regulation of apoptotic process
K	0043067	biological_process	regulation of programmed cell death
K	0043197	cellular_component	dendritic spine
K	0043204	cellular_component	perikaryon
K	0043292	cellular_component	contractile muscle fiber
K	0044877	molecular_function	protein-containing complex binding
K	0045892	biological_process	negative regulation of DNA-templated transcription
K	0046872	molecular_function	metal ion binding
K	0050821	biological_process	protein stabilization
K	0051082	molecular_function	unfolded protein binding
K	0051403	biological_process	stress-activated MAPK cascade
K	0070062	cellular_component	extracellular exosome
K	0071480	biological_process	cellular response to gamma radiation
K	0097060	cellular_component	synaptic membrane
K	0097512	cellular_component	cardiac myofibril
K	1905907	biological_process	negative regulation of amyloid fibril formation
K	2000378	biological_process	negative regulation of reactive oxygen species metabolic process
L	0001540	molecular_function	amyloid-beta binding
L	0005198	molecular_function	structural molecule activity
L	0005212	molecular_function	structural constituent of eye lens
L	0005515	molecular_function	protein binding
L	0005576	cellular_component	extracellular region
L	0005634	cellular_component	nucleus
L	0005654	cellular_component	nucleoplasm
L	0005737	cellular_component	cytoplasm
L	0005739	cellular_component	mitochondrion
L	0005764	cellular_component	lysosome
L	0005829	cellular_component	cytosol
L	0005886	cellular_component	plasma membrane
L	0006457	biological_process	protein folding
L	0006936	biological_process	muscle contraction
L	0008017	molecular_function	microtubule binding
L	0008092	molecular_function	cytoskeletal protein binding
L	0009408	biological_process	response to heat
L	0009892	biological_process	negative regulation of metabolic process
L	0009986	cellular_component	cell surface
L	0030018	cellular_component	Z disc
L	0030308	biological_process	negative regulation of cell growth
L	0030424	cellular_component	axon
L	0031109	biological_process	microtubule polymerization or depolymerization
L	0031333	biological_process	negative regulation of protein-containing complex assembly
L	0031430	cellular_component	M band
L	0031674	cellular_component	I band
L	0032355	biological_process	response to estradiol
L	0032387	biological_process	negative regulation of intracellular transport
L	0032432	cellular_component	actin filament bundle
L	0032991	cellular_component	protein-containing complex
L	0042026	biological_process	protein refolding
L	0042542	biological_process	response to hydrogen peroxide
L	0042802	molecular_function	identical protein binding
L	0042803	molecular_function	protein homodimerization activity
L	0043066	biological_process	negative regulation of apoptotic process
L	0043067	biological_process	regulation of programmed cell death
L	0043197	cellular_component	dendritic spine
L	0043204	cellular_component	perikaryon
L	0043292	cellular_component	contractile muscle fiber
L	0044877	molecular_function	protein-containing complex binding
L	0045892	biological_process	negative regulation of DNA-templated transcription
L	0046872	molecular_function	metal ion binding
L	0050821	biological_process	protein stabilization
L	0051082	molecular_function	unfolded protein binding
L	0051403	biological_process	stress-activated MAPK cascade
L	0070062	cellular_component	extracellular exosome
L	0071480	biological_process	cellular response to gamma radiation
L	0097060	cellular_component	synaptic membrane
L	0097512	cellular_component	cardiac myofibril
L	1905907	biological_process	negative regulation of amyloid fibril formation
L	2000378	biological_process	negative regulation of reactive oxygen species metabolic process
M	0001540	molecular_function	amyloid-beta binding
M	0005198	molecular_function	structural molecule activity
M	0005212	molecular_function	structural constituent of eye lens
M	0005515	molecular_function	protein binding
M	0005576	cellular_component	extracellular region
M	0005634	cellular_component	nucleus
M	0005654	cellular_component	nucleoplasm
M	0005737	cellular_component	cytoplasm
M	0005739	cellular_component	mitochondrion
M	0005764	cellular_component	lysosome
M	0005829	cellular_component	cytosol
M	0005886	cellular_component	plasma membrane
M	0006457	biological_process	protein folding
M	0006936	biological_process	muscle contraction
M	0008017	molecular_function	microtubule binding
M	0008092	molecular_function	cytoskeletal protein binding
M	0009408	biological_process	response to heat
M	0009892	biological_process	negative regulation of metabolic process
M	0009986	cellular_component	cell surface
M	0030018	cellular_component	Z disc
M	0030308	biological_process	negative regulation of cell growth
M	0030424	cellular_component	axon
M	0031109	biological_process	microtubule polymerization or depolymerization
M	0031333	biological_process	negative regulation of protein-containing complex assembly
M	0031430	cellular_component	M band
M	0031674	cellular_component	I band
M	0032355	biological_process	response to estradiol
M	0032387	biological_process	negative regulation of intracellular transport
M	0032432	cellular_component	actin filament bundle
M	0032991	cellular_component	protein-containing complex
M	0042026	biological_process	protein refolding
M	0042542	biological_process	response to hydrogen peroxide
M	0042802	molecular_function	identical protein binding
M	0042803	molecular_function	protein homodimerization activity
M	0043066	biological_process	negative regulation of apoptotic process
M	0043067	biological_process	regulation of programmed cell death
M	0043197	cellular_component	dendritic spine
M	0043204	cellular_component	perikaryon
M	0043292	cellular_component	contractile muscle fiber
M	0044877	molecular_function	protein-containing complex binding
M	0045892	biological_process	negative regulation of DNA-templated transcription
M	0046872	molecular_function	metal ion binding
M	0050821	biological_process	protein stabilization
M	0051082	molecular_function	unfolded protein binding
M	0051403	biological_process	stress-activated MAPK cascade
M	0070062	cellular_component	extracellular exosome
M	0071480	biological_process	cellular response to gamma radiation
M	0097060	cellular_component	synaptic membrane
M	0097512	cellular_component	cardiac myofibril
M	1905907	biological_process	negative regulation of amyloid fibril formation
M	2000378	biological_process	negative regulation of reactive oxygen species metabolic process
N	0001540	molecular_function	amyloid-beta binding
N	0005198	molecular_function	structural molecule activity
N	0005212	molecular_function	structural constituent of eye lens
N	0005515	molecular_function	protein binding
N	0005576	cellular_component	extracellular region
N	0005634	cellular_component	nucleus
N	0005654	cellular_component	nucleoplasm
N	0005737	cellular_component	cytoplasm
N	0005739	cellular_component	mitochondrion
N	0005764	cellular_component	lysosome
N	0005829	cellular_component	cytosol
N	0005886	cellular_component	plasma membrane
N	0006457	biological_process	protein folding
N	0006936	biological_process	muscle contraction
N	0008017	molecular_function	microtubule binding
N	0008092	molecular_function	cytoskeletal protein binding
N	0009408	biological_process	response to heat
N	0009892	biological_process	negative regulation of metabolic process
N	0009986	cellular_component	cell surface
N	0030018	cellular_component	Z disc
N	0030308	biological_process	negative regulation of cell growth
N	0030424	cellular_component	axon
N	0031109	biological_process	microtubule polymerization or depolymerization
N	0031333	biological_process	negative regulation of protein-containing complex assembly
N	0031430	cellular_component	M band
N	0031674	cellular_component	I band
N	0032355	biological_process	response to estradiol
N	0032387	biological_process	negative regulation of intracellular transport
N	0032432	cellular_component	actin filament bundle
N	0032991	cellular_component	protein-containing complex
N	0042026	biological_process	protein refolding
N	0042542	biological_process	response to hydrogen peroxide
N	0042802	molecular_function	identical protein binding
N	0042803	molecular_function	protein homodimerization activity
N	0043066	biological_process	negative regulation of apoptotic process
N	0043067	biological_process	regulation of programmed cell death
N	0043197	cellular_component	dendritic spine
N	0043204	cellular_component	perikaryon
N	0043292	cellular_component	contractile muscle fiber
N	0044877	molecular_function	protein-containing complex binding
N	0045892	biological_process	negative regulation of DNA-templated transcription
N	0046872	molecular_function	metal ion binding
N	0050821	biological_process	protein stabilization
N	0051082	molecular_function	unfolded protein binding
N	0051403	biological_process	stress-activated MAPK cascade
N	0070062	cellular_component	extracellular exosome
N	0071480	biological_process	cellular response to gamma radiation
N	0097060	cellular_component	synaptic membrane
N	0097512	cellular_component	cardiac myofibril
N	1905907	biological_process	negative regulation of amyloid fibril formation
N	2000378	biological_process	negative regulation of reactive oxygen species metabolic process
O	0001540	molecular_function	amyloid-beta binding
O	0005198	molecular_function	structural molecule activity
O	0005212	molecular_function	structural constituent of eye lens
O	0005515	molecular_function	protein binding
O	0005576	cellular_component	extracellular region
O	0005634	cellular_component	nucleus
O	0005654	cellular_component	nucleoplasm
O	0005737	cellular_component	cytoplasm
O	0005739	cellular_component	mitochondrion
O	0005764	cellular_component	lysosome
O	0005829	cellular_component	cytosol
O	0005886	cellular_component	plasma membrane
O	0006457	biological_process	protein folding
O	0006936	biological_process	muscle contraction
O	0008017	molecular_function	microtubule binding
O	0008092	molecular_function	cytoskeletal protein binding
O	0009408	biological_process	response to heat
O	0009892	biological_process	negative regulation of metabolic process
O	0009986	cellular_component	cell surface
O	0030018	cellular_component	Z disc
O	0030308	biological_process	negative regulation of cell growth
O	0030424	cellular_component	axon
O	0031109	biological_process	microtubule polymerization or depolymerization
O	0031333	biological_process	negative regulation of protein-containing complex assembly
O	0031430	cellular_component	M band
O	0031674	cellular_component	I band
O	0032355	biological_process	response to estradiol
O	0032387	biological_process	negative regulation of intracellular transport
O	0032432	cellular_component	actin filament bundle
O	0032991	cellular_component	protein-containing complex
O	0042026	biological_process	protein refolding
O	0042542	biological_process	response to hydrogen peroxide
O	0042802	molecular_function	identical protein binding
O	0042803	molecular_function	protein homodimerization activity
O	0043066	biological_process	negative regulation of apoptotic process
O	0043067	biological_process	regulation of programmed cell death
O	0043197	cellular_component	dendritic spine
O	0043204	cellular_component	perikaryon
O	0043292	cellular_component	contractile muscle fiber
O	0044877	molecular_function	protein-containing complex binding
O	0045892	biological_process	negative regulation of DNA-templated transcription
O	0046872	molecular_function	metal ion binding
O	0050821	biological_process	protein stabilization
O	0051082	molecular_function	unfolded protein binding
O	0051403	biological_process	stress-activated MAPK cascade
O	0070062	cellular_component	extracellular exosome
O	0071480	biological_process	cellular response to gamma radiation
O	0097060	cellular_component	synaptic membrane
O	0097512	cellular_component	cardiac myofibril
O	1905907	biological_process	negative regulation of amyloid fibril formation
O	2000378	biological_process	negative regulation of reactive oxygen species metabolic process
P	0001540	molecular_function	amyloid-beta binding
P	0005198	molecular_function	structural molecule activity
P	0005212	molecular_function	structural constituent of eye lens
P	0005515	molecular_function	protein binding
P	0005576	cellular_component	extracellular region
P	0005634	cellular_component	nucleus
P	0005654	cellular_component	nucleoplasm
P	0005737	cellular_component	cytoplasm
P	0005739	cellular_component	mitochondrion
P	0005764	cellular_component	lysosome
P	0005829	cellular_component	cytosol
P	0005886	cellular_component	plasma membrane
P	0006457	biological_process	protein folding
P	0006936	biological_process	muscle contraction
P	0008017	molecular_function	microtubule binding
P	0008092	molecular_function	cytoskeletal protein binding
P	0009408	biological_process	response to heat
P	0009892	biological_process	negative regulation of metabolic process
P	0009986	cellular_component	cell surface
P	0030018	cellular_component	Z disc
P	0030308	biological_process	negative regulation of cell growth
P	0030424	cellular_component	axon
P	0031109	biological_process	microtubule polymerization or depolymerization
P	0031333	biological_process	negative regulation of protein-containing complex assembly
P	0031430	cellular_component	M band
P	0031674	cellular_component	I band
P	0032355	biological_process	response to estradiol
P	0032387	biological_process	negative regulation of intracellular transport
P	0032432	cellular_component	actin filament bundle
P	0032991	cellular_component	protein-containing complex
P	0042026	biological_process	protein refolding
P	0042542	biological_process	response to hydrogen peroxide
P	0042802	molecular_function	identical protein binding
P	0042803	molecular_function	protein homodimerization activity
P	0043066	biological_process	negative regulation of apoptotic process
P	0043067	biological_process	regulation of programmed cell death
P	0043197	cellular_component	dendritic spine
P	0043204	cellular_component	perikaryon
P	0043292	cellular_component	contractile muscle fiber
P	0044877	molecular_function	protein-containing complex binding
P	0045892	biological_process	negative regulation of DNA-templated transcription
P	0046872	molecular_function	metal ion binding
P	0050821	biological_process	protein stabilization
P	0051082	molecular_function	unfolded protein binding
P	0051403	biological_process	stress-activated MAPK cascade
P	0070062	cellular_component	extracellular exosome
P	0071480	biological_process	cellular response to gamma radiation
P	0097060	cellular_component	synaptic membrane
P	0097512	cellular_component	cardiac myofibril
P	1905907	biological_process	negative regulation of amyloid fibril formation
P	2000378	biological_process	negative regulation of reactive oxygen species metabolic process
Q	0001540	molecular_function	amyloid-beta binding
Q	0005198	molecular_function	structural molecule activity
Q	0005212	molecular_function	structural constituent of eye lens
Q	0005515	molecular_function	protein binding
Q	0005576	cellular_component	extracellular region
Q	0005634	cellular_component	nucleus
Q	0005654	cellular_component	nucleoplasm
Q	0005737	cellular_component	cytoplasm
Q	0005739	cellular_component	mitochondrion
Q	0005764	cellular_component	lysosome
Q	0005829	cellular_component	cytosol
Q	0005886	cellular_component	plasma membrane
Q	0006457	biological_process	protein folding
Q	0006936	biological_process	muscle contraction
Q	0008017	molecular_function	microtubule binding
Q	0008092	molecular_function	cytoskeletal protein binding
Q	0009408	biological_process	response to heat
Q	0009892	biological_process	negative regulation of metabolic process
Q	0009986	cellular_component	cell surface
Q	0030018	cellular_component	Z disc
Q	0030308	biological_process	negative regulation of cell growth
Q	0030424	cellular_component	axon
Q	0031109	biological_process	microtubule polymerization or depolymerization
Q	0031333	biological_process	negative regulation of protein-containing complex assembly
Q	0031430	cellular_component	M band
Q	0031674	cellular_component	I band
Q	0032355	biological_process	response to estradiol
Q	0032387	biological_process	negative regulation of intracellular transport
Q	0032432	cellular_component	actin filament bundle
Q	0032991	cellular_component	protein-containing complex
Q	0042026	biological_process	protein refolding
Q	0042542	biological_process	response to hydrogen peroxide
Q	0042802	molecular_function	identical protein binding
Q	0042803	molecular_function	protein homodimerization activity
Q	0043066	biological_process	negative regulation of apoptotic process
Q	0043067	biological_process	regulation of programmed cell death
Q	0043197	cellular_component	dendritic spine
Q	0043204	cellular_component	perikaryon
Q	0043292	cellular_component	contractile muscle fiber
Q	0044877	molecular_function	protein-containing complex binding
Q	0045892	biological_process	negative regulation of DNA-templated transcription
Q	0046872	molecular_function	metal ion binding
Q	0050821	biological_process	protein stabilization
Q	0051082	molecular_function	unfolded protein binding
Q	0051403	biological_process	stress-activated MAPK cascade
Q	0070062	cellular_component	extracellular exosome
Q	0071480	biological_process	cellular response to gamma radiation
Q	0097060	cellular_component	synaptic membrane
Q	0097512	cellular_component	cardiac myofibril
Q	1905907	biological_process	negative regulation of amyloid fibril formation
Q	2000378	biological_process	negative regulation of reactive oxygen species metabolic process
R	0001540	molecular_function	amyloid-beta binding
R	0005198	molecular_function	structural molecule activity
R	0005212	molecular_function	structural constituent of eye lens
R	0005515	molecular_function	protein binding
R	0005576	cellular_component	extracellular region
R	0005634	cellular_component	nucleus
R	0005654	cellular_component	nucleoplasm
R	0005737	cellular_component	cytoplasm
R	0005739	cellular_component	mitochondrion
R	0005764	cellular_component	lysosome
R	0005829	cellular_component	cytosol
R	0005886	cellular_component	plasma membrane
R	0006457	biological_process	protein folding
R	0006936	biological_process	muscle contraction
R	0008017	molecular_function	microtubule binding
R	0008092	molecular_function	cytoskeletal protein binding
R	0009408	biological_process	response to heat
R	0009892	biological_process	negative regulation of metabolic process
R	0009986	cellular_component	cell surface
R	0030018	cellular_component	Z disc
R	0030308	biological_process	negative regulation of cell growth
R	0030424	cellular_component	axon
R	0031109	biological_process	microtubule polymerization or depolymerization
R	0031333	biological_process	negative regulation of protein-containing complex assembly
R	0031430	cellular_component	M band
R	0031674	cellular_component	I band
R	0032355	biological_process	response to estradiol
R	0032387	biological_process	negative regulation of intracellular transport
R	0032432	cellular_component	actin filament bundle
R	0032991	cellular_component	protein-containing complex
R	0042026	biological_process	protein refolding
R	0042542	biological_process	response to hydrogen peroxide
R	0042802	molecular_function	identical protein binding
R	0042803	molecular_function	protein homodimerization activity
R	0043066	biological_process	negative regulation of apoptotic process
R	0043067	biological_process	regulation of programmed cell death
R	0043197	cellular_component	dendritic spine
R	0043204	cellular_component	perikaryon
R	0043292	cellular_component	contractile muscle fiber
R	0044877	molecular_function	protein-containing complex binding
R	0045892	biological_process	negative regulation of DNA-templated transcription
R	0046872	molecular_function	metal ion binding
R	0050821	biological_process	protein stabilization
R	0051082	molecular_function	unfolded protein binding
R	0051403	biological_process	stress-activated MAPK cascade
R	0070062	cellular_component	extracellular exosome
R	0071480	biological_process	cellular response to gamma radiation
R	0097060	cellular_component	synaptic membrane
R	0097512	cellular_component	cardiac myofibril
R	1905907	biological_process	negative regulation of amyloid fibril formation
R	2000378	biological_process	negative regulation of reactive oxygen species metabolic process
S	0001540	molecular_function	amyloid-beta binding
S	0005198	molecular_function	structural molecule activity
S	0005212	molecular_function	structural constituent of eye lens
S	0005515	molecular_function	protein binding
S	0005576	cellular_component	extracellular region
S	0005634	cellular_component	nucleus
S	0005654	cellular_component	nucleoplasm
S	0005737	cellular_component	cytoplasm
S	0005739	cellular_component	mitochondrion
S	0005764	cellular_component	lysosome
S	0005829	cellular_component	cytosol
S	0005886	cellular_component	plasma membrane
S	0006457	biological_process	protein folding
S	0006936	biological_process	muscle contraction
S	0008017	molecular_function	microtubule binding
S	0008092	molecular_function	cytoskeletal protein binding
S	0009408	biological_process	response to heat
S	0009892	biological_process	negative regulation of metabolic process
S	0009986	cellular_component	cell surface
S	0030018	cellular_component	Z disc
S	0030308	biological_process	negative regulation of cell growth
S	0030424	cellular_component	axon
S	0031109	biological_process	microtubule polymerization or depolymerization
S	0031333	biological_process	negative regulation of protein-containing complex assembly
S	0031430	cellular_component	M band
S	0031674	cellular_component	I band
S	0032355	biological_process	response to estradiol
S	0032387	biological_process	negative regulation of intracellular transport
S	0032432	cellular_component	actin filament bundle
S	0032991	cellular_component	protein-containing complex
S	0042026	biological_process	protein refolding
S	0042542	biological_process	response to hydrogen peroxide
S	0042802	molecular_function	identical protein binding
S	0042803	molecular_function	protein homodimerization activity
S	0043066	biological_process	negative regulation of apoptotic process
S	0043067	biological_process	regulation of programmed cell death
S	0043197	cellular_component	dendritic spine
S	0043204	cellular_component	perikaryon
S	0043292	cellular_component	contractile muscle fiber
S	0044877	molecular_function	protein-containing complex binding
S	0045892	biological_process	negative regulation of DNA-templated transcription
S	0046872	molecular_function	metal ion binding
S	0050821	biological_process	protein stabilization
S	0051082	molecular_function	unfolded protein binding
S	0051403	biological_process	stress-activated MAPK cascade
S	0070062	cellular_component	extracellular exosome
S	0071480	biological_process	cellular response to gamma radiation
S	0097060	cellular_component	synaptic membrane
S	0097512	cellular_component	cardiac myofibril
S	1905907	biological_process	negative regulation of amyloid fibril formation
S	2000378	biological_process	negative regulation of reactive oxygen species metabolic process
T	0001540	molecular_function	amyloid-beta binding
T	0005198	molecular_function	structural molecule activity
T	0005212	molecular_function	structural constituent of eye lens
T	0005515	molecular_function	protein binding
T	0005576	cellular_component	extracellular region
T	0005634	cellular_component	nucleus
T	0005654	cellular_component	nucleoplasm
T	0005737	cellular_component	cytoplasm
T	0005739	cellular_component	mitochondrion
T	0005764	cellular_component	lysosome
T	0005829	cellular_component	cytosol
T	0005886	cellular_component	plasma membrane
T	0006457	biological_process	protein folding
T	0006936	biological_process	muscle contraction
T	0008017	molecular_function	microtubule binding
T	0008092	molecular_function	cytoskeletal protein binding
T	0009408	biological_process	response to heat
T	0009892	biological_process	negative regulation of metabolic process
T	0009986	cellular_component	cell surface
T	0030018	cellular_component	Z disc
T	0030308	biological_process	negative regulation of cell growth
T	0030424	cellular_component	axon
T	0031109	biological_process	microtubule polymerization or depolymerization
T	0031333	biological_process	negative regulation of protein-containing complex assembly
T	0031430	cellular_component	M band
T	0031674	cellular_component	I band
T	0032355	biological_process	response to estradiol
T	0032387	biological_process	negative regulation of intracellular transport
T	0032432	cellular_component	actin filament bundle
T	0032991	cellular_component	protein-containing complex
T	0042026	biological_process	protein refolding
T	0042542	biological_process	response to hydrogen peroxide
T	0042802	molecular_function	identical protein binding
T	0042803	molecular_function	protein homodimerization activity
T	0043066	biological_process	negative regulation of apoptotic process
T	0043067	biological_process	regulation of programmed cell death
T	0043197	cellular_component	dendritic spine
T	0043204	cellular_component	perikaryon
T	0043292	cellular_component	contractile muscle fiber
T	0044877	molecular_function	protein-containing complex binding
T	0045892	biological_process	negative regulation of DNA-templated transcription
T	0046872	molecular_function	metal ion binding
T	0050821	biological_process	protein stabilization
T	0051082	molecular_function	unfolded protein binding
T	0051403	biological_process	stress-activated MAPK cascade
T	0070062	cellular_component	extracellular exosome
T	0071480	biological_process	cellular response to gamma radiation
T	0097060	cellular_component	synaptic membrane
T	0097512	cellular_component	cardiac myofibril
T	1905907	biological_process	negative regulation of amyloid fibril formation
T	2000378	biological_process	negative regulation of reactive oxygen species metabolic process
U	0001540	molecular_function	amyloid-beta binding
U	0005198	molecular_function	structural molecule activity
U	0005212	molecular_function	structural constituent of eye lens
U	0005515	molecular_function	protein binding
U	0005576	cellular_component	extracellular region
U	0005634	cellular_component	nucleus
U	0005654	cellular_component	nucleoplasm
U	0005737	cellular_component	cytoplasm
U	0005739	cellular_component	mitochondrion
U	0005764	cellular_component	lysosome
U	0005829	cellular_component	cytosol
U	0005886	cellular_component	plasma membrane
U	0006457	biological_process	protein folding
U	0006936	biological_process	muscle contraction
U	0008017	molecular_function	microtubule binding
U	0008092	molecular_function	cytoskeletal protein binding
U	0009408	biological_process	response to heat
U	0009892	biological_process	negative regulation of metabolic process
U	0009986	cellular_component	cell surface
U	0030018	cellular_component	Z disc
U	0030308	biological_process	negative regulation of cell growth
U	0030424	cellular_component	axon
U	0031109	biological_process	microtubule polymerization or depolymerization
U	0031333	biological_process	negative regulation of protein-containing complex assembly
U	0031430	cellular_component	M band
U	0031674	cellular_component	I band
U	0032355	biological_process	response to estradiol
U	0032387	biological_process	negative regulation of intracellular transport
U	0032432	cellular_component	actin filament bundle
U	0032991	cellular_component	protein-containing complex
U	0042026	biological_process	protein refolding
U	0042542	biological_process	response to hydrogen peroxide
U	0042802	molecular_function	identical protein binding
U	0042803	molecular_function	protein homodimerization activity
U	0043066	biological_process	negative regulation of apoptotic process
U	0043067	biological_process	regulation of programmed cell death
U	0043197	cellular_component	dendritic spine
U	0043204	cellular_component	perikaryon
U	0043292	cellular_component	contractile muscle fiber
U	0044877	molecular_function	protein-containing complex binding
U	0045892	biological_process	negative regulation of DNA-templated transcription
U	0046872	molecular_function	metal ion binding
U	0050821	biological_process	protein stabilization
U	0051082	molecular_function	unfolded protein binding
U	0051403	biological_process	stress-activated MAPK cascade
U	0070062	cellular_component	extracellular exosome
U	0071480	biological_process	cellular response to gamma radiation
U	0097060	cellular_component	synaptic membrane
U	0097512	cellular_component	cardiac myofibril
U	1905907	biological_process	negative regulation of amyloid fibril formation
U	2000378	biological_process	negative regulation of reactive oxygen species metabolic process
V	0001540	molecular_function	amyloid-beta binding
V	0005198	molecular_function	structural molecule activity
V	0005212	molecular_function	structural constituent of eye lens
V	0005515	molecular_function	protein binding
V	0005576	cellular_component	extracellular region
V	0005634	cellular_component	nucleus
V	0005654	cellular_component	nucleoplasm
V	0005737	cellular_component	cytoplasm
V	0005739	cellular_component	mitochondrion
V	0005764	cellular_component	lysosome
V	0005829	cellular_component	cytosol
V	0005886	cellular_component	plasma membrane
V	0006457	biological_process	protein folding
V	0006936	biological_process	muscle contraction
V	0008017	molecular_function	microtubule binding
V	0008092	molecular_function	cytoskeletal protein binding
V	0009408	biological_process	response to heat
V	0009892	biological_process	negative regulation of metabolic process
V	0009986	cellular_component	cell surface
V	0030018	cellular_component	Z disc
V	0030308	biological_process	negative regulation of cell growth
V	0030424	cellular_component	axon
V	0031109	biological_process	microtubule polymerization or depolymerization
V	0031333	biological_process	negative regulation of protein-containing complex assembly
V	0031430	cellular_component	M band
V	0031674	cellular_component	I band
V	0032355	biological_process	response to estradiol
V	0032387	biological_process	negative regulation of intracellular transport
V	0032432	cellular_component	actin filament bundle
V	0032991	cellular_component	protein-containing complex
V	0042026	biological_process	protein refolding
V	0042542	biological_process	response to hydrogen peroxide
V	0042802	molecular_function	identical protein binding
V	0042803	molecular_function	protein homodimerization activity
V	0043066	biological_process	negative regulation of apoptotic process
V	0043067	biological_process	regulation of programmed cell death
V	0043197	cellular_component	dendritic spine
V	0043204	cellular_component	perikaryon
V	0043292	cellular_component	contractile muscle fiber
V	0044877	molecular_function	protein-containing complex binding
V	0045892	biological_process	negative regulation of DNA-templated transcription
V	0046872	molecular_function	metal ion binding
V	0050821	biological_process	protein stabilization
V	0051082	molecular_function	unfolded protein binding
V	0051403	biological_process	stress-activated MAPK cascade
V	0070062	cellular_component	extracellular exosome
V	0071480	biological_process	cellular response to gamma radiation
V	0097060	cellular_component	synaptic membrane
V	0097512	cellular_component	cardiac myofibril
V	1905907	biological_process	negative regulation of amyloid fibril formation
V	2000378	biological_process	negative regulation of reactive oxygen species metabolic process
W	0001540	molecular_function	amyloid-beta binding
W	0005198	molecular_function	structural molecule activity
W	0005212	molecular_function	structural constituent of eye lens
W	0005515	molecular_function	protein binding
W	0005576	cellular_component	extracellular region
W	0005634	cellular_component	nucleus
W	0005654	cellular_component	nucleoplasm
W	0005737	cellular_component	cytoplasm
W	0005739	cellular_component	mitochondrion
W	0005764	cellular_component	lysosome
W	0005829	cellular_component	cytosol
W	0005886	cellular_component	plasma membrane
W	0006457	biological_process	protein folding
W	0006936	biological_process	muscle contraction
W	0008017	molecular_function	microtubule binding
W	0008092	molecular_function	cytoskeletal protein binding
W	0009408	biological_process	response to heat
W	0009892	biological_process	negative regulation of metabolic process
W	0009986	cellular_component	cell surface
W	0030018	cellular_component	Z disc
W	0030308	biological_process	negative regulation of cell growth
W	0030424	cellular_component	axon
W	0031109	biological_process	microtubule polymerization or depolymerization
W	0031333	biological_process	negative regulation of protein-containing complex assembly
W	0031430	cellular_component	M band
W	0031674	cellular_component	I band
W	0032355	biological_process	response to estradiol
W	0032387	biological_process	negative regulation of intracellular transport
W	0032432	cellular_component	actin filament bundle
W	0032991	cellular_component	protein-containing complex
W	0042026	biological_process	protein refolding
W	0042542	biological_process	response to hydrogen peroxide
W	0042802	molecular_function	identical protein binding
W	0042803	molecular_function	protein homodimerization activity
W	0043066	biological_process	negative regulation of apoptotic process
W	0043067	biological_process	regulation of programmed cell death
W	0043197	cellular_component	dendritic spine
W	0043204	cellular_component	perikaryon
W	0043292	cellular_component	contractile muscle fiber
W	0044877	molecular_function	protein-containing complex binding
W	0045892	biological_process	negative regulation of DNA-templated transcription
W	0046872	molecular_function	metal ion binding
W	0050821	biological_process	protein stabilization
W	0051082	molecular_function	unfolded protein binding
W	0051403	biological_process	stress-activated MAPK cascade
W	0070062	cellular_component	extracellular exosome
W	0071480	biological_process	cellular response to gamma radiation
W	0097060	cellular_component	synaptic membrane
W	0097512	cellular_component	cardiac myofibril
W	1905907	biological_process	negative regulation of amyloid fibril formation
W	2000378	biological_process	negative regulation of reactive oxygen species metabolic process
X	0001540	molecular_function	amyloid-beta binding
X	0005198	molecular_function	structural molecule activity
X	0005212	molecular_function	structural constituent of eye lens
X	0005515	molecular_function	protein binding
X	0005576	cellular_component	extracellular region
X	0005634	cellular_component	nucleus
X	0005654	cellular_component	nucleoplasm
X	0005737	cellular_component	cytoplasm
X	0005739	cellular_component	mitochondrion
X	0005764	cellular_component	lysosome
X	0005829	cellular_component	cytosol
X	0005886	cellular_component	plasma membrane
X	0006457	biological_process	protein folding
X	0006936	biological_process	muscle contraction
X	0008017	molecular_function	microtubule binding
X	0008092	molecular_function	cytoskeletal protein binding
X	0009408	biological_process	response to heat
X	0009892	biological_process	negative regulation of metabolic process
X	0009986	cellular_component	cell surface
X	0030018	cellular_component	Z disc
X	0030308	biological_process	negative regulation of cell growth
X	0030424	cellular_component	axon
X	0031109	biological_process	microtubule polymerization or depolymerization
X	0031333	biological_process	negative regulation of protein-containing complex assembly
X	0031430	cellular_component	M band
X	0031674	cellular_component	I band
X	0032355	biological_process	response to estradiol
X	0032387	biological_process	negative regulation of intracellular transport
X	0032432	cellular_component	actin filament bundle
X	0032991	cellular_component	protein-containing complex
X	0042026	biological_process	protein refolding
X	0042542	biological_process	response to hydrogen peroxide
X	0042802	molecular_function	identical protein binding
X	0042803	molecular_function	protein homodimerization activity
X	0043066	biological_process	negative regulation of apoptotic process
X	0043067	biological_process	regulation of programmed cell death
X	0043197	cellular_component	dendritic spine
X	0043204	cellular_component	perikaryon
X	0043292	cellular_component	contractile muscle fiber
X	0044877	molecular_function	protein-containing complex binding
X	0045892	biological_process	negative regulation of DNA-templated transcription
X	0046872	molecular_function	metal ion binding
X	0050821	biological_process	protein stabilization
X	0051082	molecular_function	unfolded protein binding
X	0051403	biological_process	stress-activated MAPK cascade
X	0070062	cellular_component	extracellular exosome
X	0071480	biological_process	cellular response to gamma radiation
X	0097060	cellular_component	synaptic membrane
X	0097512	cellular_component	cardiac myofibril
X	1905907	biological_process	negative regulation of amyloid fibril formation
X	2000378	biological_process	negative regulation of reactive oxygen species metabolic process

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2592
Details	Domain: {"description":"sHSP","evidences":[{"source":"PROSITE-ProRule","id":"PRU00285","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	696
Details	Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	48
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	72
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22890888","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	72
Details	Site: {"description":"Susceptible to oxidation"}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	24
Details	Modified residue: {"description":"N-acetylmethionine","evidences":[{"source":"PubMed","id":"8142454","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"838078","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	24
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"8175657","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	24
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"11158243","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8175657","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	24
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"11158243","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8175657","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	24
Details	Modified residue: {"description":"N6-acetyllysine; partial","evidences":[{"source":"PubMed","id":"11369851","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22120592","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	24
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"22120592","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	24
Details	Glycosylation: {"description":"O-linked (GlcNAc) serine","evidences":[{"source":"PubMed","id":"28939839","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	24
Details	Glycosylation: {"description":"O-linked (GlcNAc) threonine","evidences":[{"source":"UniProtKB","id":"P23928","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---