2YCK

methyltransferase bound with tetrahydrofolate

Functional Information from GO Data

Chain	GOid	namespace	contents
X	0003674	molecular_function	molecular_function
X	0005829	cellular_component	cytosol
X	0008168	molecular_function	methyltransferase activity
X	0008705	molecular_function	methionine synthase activity
X	0009086	biological_process	methionine biosynthetic process
X	0032259	biological_process	methylation
X	0042558	biological_process	pteridine-containing compound metabolic process
X	0044237	biological_process	cellular metabolic process
X	0046653	biological_process	tetrahydrofolate metabolic process
X	0046872	molecular_function	metal ion binding
X	0050667	biological_process	homocysteine metabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 X 1264

Chain	Residue
X	SER-1
X	HIS0
X	MET1
X	HOH2117

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site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 X 1265

Chain	Residue
X	HIS0
X	ARG193
X	HOH2118

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site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 X 1266

Chain	Residue
X	ARG91
X	GLY92

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site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 X 1267

Chain	Residue
X	ARG8
X	TRP31
X	HOH2119

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site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 X 1268

Chain	Residue
X	ASP232
X	ASP233
X	ASP234
X	ALA235
X	HOH2098

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site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 X 1269

Chain	Residue
X	ALA51
X	ASP52
X	ASP53
X	PRO54

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site_id	AC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 X 1270

Chain	Residue
X	TRP104
X	HOH2120

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site_id	AC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE GOL X 1271

Chain	Residue
X	GLY92
X	HIS93

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site_id	AC9
Number of Residues	20
Details	BINDING SITE FOR RESIDUE THG X 7216

Chain	Residue
X	MET12
X	PHE13
X	ASP76
X	ASN97
X	LEU123
X	ASP161
X	GLY197
X	SER199
X	ASN200
X	GLN203
X	LYS204
X	ARG208
X	ILE228
X	HOH2008
X	HOH2009
X	HOH2060
X	HOH2124
X	HOH2125
X	HOH2126
X	HOH2127

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