2YC1

Crystal structure of the human derived single chain antibody fragment (scFv) 9004G in complex with Cn2 toxin from the scorpion Centruroides noxius Hoffmann

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0005576	cellular_component	extracellular region
C	0006952	biological_process	defense response
C	0008200	molecular_function	ion channel inhibitor activity
C	0019871	molecular_function	sodium channel inhibitor activity
C	0035821	biological_process	modulation of process of another organism
C	0090729	molecular_function	toxin activity
F	0005576	cellular_component	extracellular region
F	0006952	biological_process	defense response
F	0008200	molecular_function	ion channel inhibitor activity
F	0019871	molecular_function	sodium channel inhibitor activity
F	0035821	biological_process	modulation of process of another organism
F	0090729	molecular_function	toxin activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL C 1066

Chain	Residue
B	SER160
B	ARG162
C	TYR33
C	GLY34
C	LYS35
C	GOL1067
C	GOL1068

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL C 1067

Chain	Residue
B	ARG224
B	HOH2029
C	GOL1066
B	SER160
B	ARG162

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL E 1240

Chain	Residue
E	SER160
E	ARG162
E	ARG224
E	GOL1242
E	HOH2024
E	HOH2072

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL E 1241

Chain	Residue
E	GLN169
E	LYS171
E	ARG177
E	PRO191
E	GLU213
E	ASP214

---

site_id	AC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL E 1242

Chain	Residue
E	SER160
E	ARG162
E	GOL1240
F	TYR33
F	GLY34
F	LYS35
F	GOL1066

---

site_id	AC6
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL C 1068

Chain	Residue
C	TYR33
C	GLY34
C	LYS35
C	GLY36
C	HIS50
C	LEU51
C	TYR52
C	GOL1066

---

site_id	AC7
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL F 1066

Chain	Residue
E	GOL1242
F	TYR33
F	GLY34
F	LYS35
F	GLY36
F	ALA37
F	HIS50
F	LEU51
F	TYR52

---

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL D 1118

Chain	Residue
A	SER54
C	ARG27
D	SER17
D	GLN82
D	HOH2108

---

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A 1118

Chain	Residue
A	SER17
A	GLN82
A	HOH2131
D	SER54
F	ARG27

---