Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004851 | molecular_function | uroporphyrin-III C-methyltransferase activity |
| A | 0006779 | biological_process | porphyrin-containing compound biosynthetic process |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0019354 | biological_process | siroheme biosynthetic process |
| A | 0032259 | biological_process | methylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE SAH A 1267 |
| Chain | Residue |
| A | PRO27 |
| A | CYS138 |
| A | TYR185 |
| A | MET186 |
| A | VAL212 |
| A | GLN214 |
| A | GLY215 |
| A | GLN217 |
| A | PRO242 |
| A | THR243 |
| A | LEU244 |
| A | LEU52 |
| A | UP21268 |
| A | HOH2018 |
| A | HOH2039 |
| A | HOH2123 |
| A | GLY103 |
| A | GLY104 |
| A | ASP105 |
| A | ILE108 |
| A | PHE109 |
| A | THR133 |
| A | ALA134 |
| site_id | AC2 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE UP2 A 1268 |
| Chain | Residue |
| A | ASP50 |
| A | ARG51 |
| A | LEU52 |
| A | PHE109 |
| A | ARG111 |
| A | ARG149 |
| A | HIS161 |
| A | LEU162 |
| A | GLN163 |
| A | MET186 |
| A | LEU188 |
| A | GLY189 |
| A | PRO241 |
| A | SAH1267 |
| A | HOH2042 |
| A | HOH2123 |
| A | HOH2124 |
| A | HOH2125 |
| A | HOH2126 |
| A | HOH2128 |
| A | HOH2129 |
Functional Information from PROSITE/UniProt
| site_id | PS00839 |
| Number of Residues | 15 |
| Details | SUMT_1 Uroporphyrin-III C-methyltransferase signature 1. VGAGPGdpgLLTLRA |
| Chain | Residue | Details |
| A | VAL23-ALA37 | |
| site_id | PS00840 |
| Number of Residues | 34 |
| Details | SUMT_2 Uroporphyrin-III C-methyltransferase signature 2. VvrLkgGDpfiFGrgaeelerLleagvdCqVvPG |
| Chain | Residue | Details |
| A | VAL98-GLY131 | |
