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2YB8

Crystal structure of Nurf55 in complex with Su(z)12

Functional Information from GO Data
ChainGOidnamespacecontents
B0000122biological_processnegative regulation of transcription by RNA polymerase II
B0000976molecular_functiontranscription cis-regulatory region binding
B0005515molecular_functionprotein binding
B0005634cellular_componentnucleus
B0005667cellular_componenttranscription regulator complex
B0005700cellular_componentpolytene chromosome
B0006325biological_processchromatin organization
B0006335biological_processDNA replication-dependent chromatin assembly
B0006338biological_processchromatin remodeling
B0006355biological_processregulation of DNA-templated transcription
B0007307biological_processeggshell chorion gene amplification
B0007346biological_processregulation of mitotic cell cycle
B0007379biological_processsegment specification
B0016581cellular_componentNuRD complex
B0016589cellular_componentNURF complex
B0031491molecular_functionnucleosome binding
B0031507biological_processheterochromatin formation
B0031523cellular_componentMyb complex
B0033186cellular_componentCAF-1 complex
B0034728biological_processnucleosome organization
B0035097cellular_componenthistone methyltransferase complex
B0035098cellular_componentESC/E(Z) complex
B0042393molecular_functionhistone binding
B0042803molecular_functionprotein homodimerization activity
B0042826molecular_functionhistone deacetylase binding
B0045892biological_processnegative regulation of DNA-templated transcription
B0045893biological_processpositive regulation of DNA-templated transcription
B0070822cellular_componentSin3-type complex
B0090575cellular_componentRNA polymerase II transcription regulator complex
B0140718biological_processfacultative heterochromatin formation
Functional Information from PDB Data
site_idAC1
Number of Residues8
DetailsBINDING SITE FOR RESIDUE SO4 B 1415
ChainResidue
BARG135
BLEU187
BGLN326
BGLN328
BHOH2044
BHOH2062
BHOH2087
BHOH2139

site_idAC2
Number of Residues8
DetailsBINDING SITE FOR RESIDUE SO4 B 1416
ChainResidue
BASN126
BHIS161
BPRO165
BGLU166
BHOH2038
BHOH2039
BHOH2056
BILE125

site_idAC3
Number of Residues4
DetailsBINDING SITE FOR RESIDUE SO4 B 1417
ChainResidue
BSER270
BHIS271
BTHR272
BHOH2105

Functional Information from PROSITE/UniProt
site_idPS00678
Number of Residues15
DetailsWD_REPEATS_1 Trp-Asp (WD) repeats signature. LLSAsdDhTICLWDI
ChainResidueDetails
BLEU197-ILE211
BLEU293-LEU307
BLEU337-LEU351

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues33
DetailsRepeat: {"description":"WD 1"}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues31
DetailsRepeat: {"description":"WD 2"}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues31
DetailsRepeat: {"description":"WD 3"}
ChainResidueDetails

site_idSWS_FT_FI4
Number of Residues31
DetailsRepeat: {"description":"WD 4"}
ChainResidueDetails

site_idSWS_FT_FI5
Number of Residues31
DetailsRepeat: {"description":"WD 5"}
ChainResidueDetails

site_idSWS_FT_FI6
Number of Residues31
DetailsRepeat: {"description":"WD 6"}
ChainResidueDetails

242842

PDB entries from 2025-10-08

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