2Y8A

VIM-7 with Oxidised. Structural and computational investigations of VIM-7: Insights into the substrate specificity of VIM metallo-beta- lactamases

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008270	molecular_function	zinc ion binding
A	0008800	molecular_function	beta-lactamase activity
A	0017001	biological_process	antibiotic catabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN A 1292

Chain	Residue
A	HIS116
A	HIS118
A	HIS196

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site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN A 1293

Chain	Residue
A	ASP120
A	CYS221
A	HIS263

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site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A 1294

Chain	Residue
A	HOH2034
A	HOH2040
A	ASP119
A	ASN165
A	HOH2033

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Functional Information from PROSITE/UniProt

site_id	PS00743
Number of Residues	20
Details	BETA_LACTAMASE_B_1 Beta-lactamases class B signature 1. IsTHfHDDrvGGvdvlraa.G

Chain	Residue	Details
A	ILE113-GLY133

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PDB","id":"2Y87","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2Y8A","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4D1T","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PDB","id":"2Y87","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2Y8B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4D1T","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PDB","id":"2Y8A","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4D1T","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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