2Y7F
Crystal structure of the 3-keto-5-aminohexanoate cleavage enzyme (Kce) from C. Cloacamonas acidaminovorans in complex with the substrate 3- keto-5-aminohexanoate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016740 | molecular_function | transferase activity |
| A | 0019475 | biological_process | L-lysine catabolic process to acetate |
| A | 0043720 | molecular_function | 3-keto-5-aminohexanoate cleavage activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0016740 | molecular_function | transferase activity |
| B | 0019475 | biological_process | L-lysine catabolic process to acetate |
| B | 0043720 | molecular_function | 3-keto-5-aminohexanoate cleavage activity |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0016740 | molecular_function | transferase activity |
| C | 0019475 | biological_process | L-lysine catabolic process to acetate |
| C | 0043720 | molecular_function | 3-keto-5-aminohexanoate cleavage activity |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0016740 | molecular_function | transferase activity |
| D | 0019475 | biological_process | L-lysine catabolic process to acetate |
| D | 0043720 | molecular_function | 3-keto-5-aminohexanoate cleavage activity |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 301 |
| Chain | Residue |
| A | HIS46 |
| A | HIS48 |
| A | GLU230 |
| A | KMH1276 |
| A | HOH2236 |
| site_id | AC2 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE KMH A 1276 |
| Chain | Residue |
| A | GLY84 |
| A | GLY85 |
| A | VAL87 |
| A | THR106 |
| A | ASN108 |
| A | PHE114 |
| A | TYR145 |
| A | GLU230 |
| A | ZN301 |
| A | HOH2007 |
| A | HOH2236 |
| A | HOH2237 |
| A | GLU14 |
| A | HIS46 |
| A | HIS48 |
| A | SER82 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN B 301 |
| Chain | Residue |
| B | HIS46 |
| B | HIS48 |
| B | GLU230 |
| B | KMH1276 |
| B | HOH2228 |
| site_id | AC4 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE KMH B 1276 |
| Chain | Residue |
| B | GLU14 |
| B | HIS46 |
| B | HIS48 |
| B | SER82 |
| B | GLY84 |
| B | GLY85 |
| B | VAL87 |
| B | THR106 |
| B | ASN108 |
| B | PHE114 |
| B | TYR145 |
| B | GLU230 |
| B | ZN301 |
| B | HOH2011 |
| B | HOH2228 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN C 301 |
| Chain | Residue |
| C | HIS46 |
| C | HIS48 |
| C | GLU230 |
| C | KMH1276 |
| C | HOH2198 |
| site_id | AC6 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE KMH C 1276 |
| Chain | Residue |
| C | GLU14 |
| C | HIS46 |
| C | HIS48 |
| C | SER82 |
| C | GLY84 |
| C | GLY85 |
| C | VAL87 |
| C | THR106 |
| C | ASN108 |
| C | PHE119 |
| C | TYR145 |
| C | GLU230 |
| C | ZN301 |
| C | HOH2198 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN D 301 |
| Chain | Residue |
| D | HIS46 |
| D | HIS48 |
| D | GLU230 |
| D | KMH1276 |
| D | HOH2209 |
| site_id | AC8 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE KMH D 1276 |
| Chain | Residue |
| D | GLU14 |
| D | HIS46 |
| D | HIS48 |
| D | SER82 |
| D | GLY84 |
| D | GLY85 |
| D | VAL87 |
| D | THR106 |
| D | ASN108 |
| D | PHE119 |
| D | TYR145 |
| D | GLU230 |
| D | ZN301 |
| D | HOH2008 |
| D | HOH2209 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG D 1277 |
| Chain | Residue |
| A | HOH2013 |
| B | HOH2086 |
| B | HOH2087 |
| D | ASP61 |
| D | GLU65 |
| D | HOH2059 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 20 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:21632536, ECO:0007744|PDB:2Y7F |
| Chain | Residue | Details |
| A | GLU14 | |
| B | ASN108 | |
| C | GLU14 | |
| C | SER82 | |
| C | GLY85 | |
| C | THR106 | |
| C | ASN108 | |
| D | GLU14 | |
| D | SER82 | |
| D | GLY85 | |
| D | THR106 | |
| A | SER82 | |
| D | ASN108 | |
| A | GLY85 | |
| A | THR106 | |
| A | ASN108 | |
| B | GLU14 | |
| B | SER82 | |
| B | GLY85 | |
| B | THR106 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:21632536, ECO:0007744|PDB:2Y7D, ECO:0007744|PDB:2Y7E, ECO:0007744|PDB:2Y7F, ECO:0007744|PDB:2Y7G |
| Chain | Residue | Details |
| A | HIS46 | |
| D | HIS46 | |
| D | HIS48 | |
| D | GLU230 | |
| A | HIS48 | |
| A | GLU230 | |
| B | HIS46 | |
| B | HIS48 | |
| B | GLU230 | |
| C | HIS46 | |
| C | HIS48 | |
| C | GLU230 |
