2Y7C

Atomic model of the Ocr-bound methylase complex from the Type I restriction-modification enzyme EcoKI (M2S1). Based on fitting into EM map 1534.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0009307	biological_process	DNA restriction-modification system
A	0019812	cellular_component	type I site-specific deoxyribonuclease complex
B	0003676	molecular_function	nucleic acid binding
B	0003677	molecular_function	DNA binding
B	0005515	molecular_function	protein binding
B	0005829	cellular_component	cytosol
B	0006306	biological_process	obsolete DNA methylation
B	0008168	molecular_function	methyltransferase activity
B	0008170	molecular_function	N-methyltransferase activity
B	0009007	molecular_function	site-specific DNA-methyltransferase (adenine-specific) activity
B	0009307	biological_process	DNA restriction-modification system
B	0016740	molecular_function	transferase activity
B	0019812	cellular_component	type I site-specific deoxyribonuclease complex
B	0032259	biological_process	methylation
B	0043412	biological_process	macromolecule modification
C	0003676	molecular_function	nucleic acid binding
C	0003677	molecular_function	DNA binding
C	0005515	molecular_function	protein binding
C	0005829	cellular_component	cytosol
C	0006306	biological_process	obsolete DNA methylation
C	0008168	molecular_function	methyltransferase activity
C	0008170	molecular_function	N-methyltransferase activity
C	0009007	molecular_function	site-specific DNA-methyltransferase (adenine-specific) activity
C	0009307	biological_process	DNA restriction-modification system
C	0016740	molecular_function	transferase activity
C	0019812	cellular_component	type I site-specific deoxyribonuclease complex
C	0032259	biological_process	methylation
C	0043412	biological_process	macromolecule modification
D	0019049	biological_process	virus-mediated perturbation of host defense response
D	0039503	biological_process	obsolete suppression by virus of host innate immune response
D	0099018	biological_process	symbiont-mediated evasion of host restriction-modification system
E	0019049	biological_process	virus-mediated perturbation of host defense response
E	0039503	biological_process	obsolete suppression by virus of host innate immune response
E	0099018	biological_process	symbiont-mediated evasion of host restriction-modification system

Functional Information from PROSITE/UniProt

site_id	PS00092
Number of Residues	7
Details	N6_MTASE N-6 Adenine-specific DNA methylases signature. VATNPPF

Chain	Residue	Details
B	VAL263-PHE269

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	BINDING: BINDING => ECO:0000250|UniProtKB:Q89Z59

Chain	Residue	Details
B	GLN148
B	THR178
B	GLU216
C	GLN148
C	THR178
C	GLU216

---