2Y75
The Structure of CymR (YrzC) the Global Cysteine Regulator of B. subtilis
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0001046 | molecular_function | core promoter sequence-specific DNA binding |
A | 0003677 | molecular_function | DNA binding |
A | 0003700 | molecular_function | DNA-binding transcription factor activity |
A | 0005515 | molecular_function | protein binding |
A | 0005829 | cellular_component | cytosol |
A | 0006355 | biological_process | regulation of DNA-templated transcription |
A | 0032991 | cellular_component | protein-containing complex |
A | 0032993 | cellular_component | protein-DNA complex |
A | 0042802 | molecular_function | identical protein binding |
A | 0042803 | molecular_function | protein homodimerization activity |
A | 0051291 | biological_process | protein heterooligomerization |
B | 0001046 | molecular_function | core promoter sequence-specific DNA binding |
B | 0003677 | molecular_function | DNA binding |
B | 0003700 | molecular_function | DNA-binding transcription factor activity |
B | 0005515 | molecular_function | protein binding |
B | 0005829 | cellular_component | cytosol |
B | 0006355 | biological_process | regulation of DNA-templated transcription |
B | 0032991 | cellular_component | protein-containing complex |
B | 0032993 | cellular_component | protein-DNA complex |
B | 0042802 | molecular_function | identical protein binding |
B | 0042803 | molecular_function | protein homodimerization activity |
B | 0051291 | biological_process | protein heterooligomerization |
C | 0001046 | molecular_function | core promoter sequence-specific DNA binding |
C | 0003677 | molecular_function | DNA binding |
C | 0003700 | molecular_function | DNA-binding transcription factor activity |
C | 0005515 | molecular_function | protein binding |
C | 0005829 | cellular_component | cytosol |
C | 0006355 | biological_process | regulation of DNA-templated transcription |
C | 0032991 | cellular_component | protein-containing complex |
C | 0032993 | cellular_component | protein-DNA complex |
C | 0042802 | molecular_function | identical protein binding |
C | 0042803 | molecular_function | protein homodimerization activity |
C | 0051291 | biological_process | protein heterooligomerization |
D | 0001046 | molecular_function | core promoter sequence-specific DNA binding |
D | 0003677 | molecular_function | DNA binding |
D | 0003700 | molecular_function | DNA-binding transcription factor activity |
D | 0005515 | molecular_function | protein binding |
D | 0005829 | cellular_component | cytosol |
D | 0006355 | biological_process | regulation of DNA-templated transcription |
D | 0032991 | cellular_component | protein-containing complex |
D | 0032993 | cellular_component | protein-DNA complex |
D | 0042802 | molecular_function | identical protein binding |
D | 0042803 | molecular_function | protein homodimerization activity |
D | 0051291 | biological_process | protein heterooligomerization |
E | 0001046 | molecular_function | core promoter sequence-specific DNA binding |
E | 0003677 | molecular_function | DNA binding |
E | 0003700 | molecular_function | DNA-binding transcription factor activity |
E | 0005515 | molecular_function | protein binding |
E | 0005829 | cellular_component | cytosol |
E | 0006355 | biological_process | regulation of DNA-templated transcription |
E | 0032991 | cellular_component | protein-containing complex |
E | 0032993 | cellular_component | protein-DNA complex |
E | 0042802 | molecular_function | identical protein binding |
E | 0042803 | molecular_function | protein homodimerization activity |
E | 0051291 | biological_process | protein heterooligomerization |
F | 0001046 | molecular_function | core promoter sequence-specific DNA binding |
F | 0003677 | molecular_function | DNA binding |
F | 0003700 | molecular_function | DNA-binding transcription factor activity |
F | 0005515 | molecular_function | protein binding |
F | 0005829 | cellular_component | cytosol |
F | 0006355 | biological_process | regulation of DNA-templated transcription |
F | 0032991 | cellular_component | protein-containing complex |
F | 0032993 | cellular_component | protein-DNA complex |
F | 0042802 | molecular_function | identical protein binding |
F | 0042803 | molecular_function | protein homodimerization activity |
F | 0051291 | biological_process | protein heterooligomerization |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 A 1130 |
Chain | Residue |
A | ARG51 |
A | LYS57 |
A | SER58 |
A | HOH2068 |
F | HOH2142 |
site_id | AC2 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE SO4 A 1131 |
Chain | Residue |
A | LYS113 |
A | HOH2131 |
A | HOH2132 |
A | HOH2133 |
C | HOH2029 |
A | ARG82 |
A | PRO87 |
A | ILE88 |
A | SER89 |
site_id | AC3 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE SO4 A 1132 |
Chain | Residue |
A | LYS7 |
A | HOH2135 |
C | LYS7 |
E | LYS7 |
site_id | AC4 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 B 1129 |
Chain | Residue |
B | ARG51 |
B | LYS57 |
B | SER58 |
B | HOH2076 |
B | HOH2168 |
site_id | AC5 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE SO4 B 1130 |
Chain | Residue |
B | ARG82 |
B | PRO87 |
B | ILE88 |
B | LYS113 |
B | HOH2169 |
B | HOH2170 |
site_id | AC6 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE SO4 B 1131 |
Chain | Residue |
A | SER118 |
B | GLY61 |
B | ALA62 |
site_id | AC7 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE CL B 1132 |
Chain | Residue |
B | LEU29 |
B | HOH2048 |
site_id | AC8 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE SO4 C 1130 |
Chain | Residue |
C | ARG51 |
C | LYS57 |
C | SER58 |
C | HOH2049 |
site_id | AC9 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE SO4 C 1131 |
Chain | Residue |
C | ARG82 |
C | PRO87 |
C | ILE88 |
C | SER89 |
C | LYS113 |
C | HOH2105 |
C | HOH2106 |
C | HOH2109 |
site_id | BC1 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE SO4 D 1129 |
Chain | Residue |
D | ARG51 |
D | LYS57 |
D | SER58 |
D | HOH2088 |
D | HOH2170 |
D | HOH2172 |
D | HOH2173 |
site_id | BC2 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE SO4 D 1130 |
Chain | Residue |
B | ASN37 |
D | ARG82 |
D | PRO87 |
D | ILE88 |
D | LYS113 |
D | HOH2174 |
site_id | BC3 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE CL D 1131 |
Chain | Residue |
D | SER28 |
D | LEU29 |
D | HOH2020 |
D | HOH2031 |
D | HOH2064 |
site_id | BC4 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 E 1130 |
Chain | Residue |
E | ARG51 |
E | LYS57 |
E | SER58 |
E | HOH2123 |
E | HOH2124 |
site_id | BC5 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE SO4 E 1131 |
Chain | Residue |
A | HOH2048 |
E | ARG82 |
E | PRO87 |
E | ILE88 |
E | SER89 |
E | LYS113 |
E | HOH2125 |
site_id | BC6 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE SO4 F 1130 |
Chain | Residue |
F | ARG51 |
F | LYS57 |
F | SER58 |
F | HOH2149 |
F | HOH2150 |
F | HOH2151 |
site_id | BC7 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE SO4 F 1131 |
Chain | Residue |
F | ARG82 |
F | PRO87 |
F | ILE88 |
F | ARG109 |
F | LYS113 |
F | HOH2152 |
site_id | BC8 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE SO4 F 1132 |
Chain | Residue |
F | ARG60 |
F | GLY61 |
F | HOH2153 |
F | HOH2154 |
site_id | BC9 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CL F 1133 |
Chain | Residue |
F | SER28 |
F | LEU29 |
F | HOH2010 |
F | HOH2063 |
site_id | CC1 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 F 1134 |
Chain | Residue |
F | HOH2155 |
F | HOH2157 |
B | LYS7 |
D | LYS7 |
F | LYS7 |
Functional Information from PROSITE/UniProt
site_id | PS01332 |
Number of Residues | 19 |
Details | HTH_RRF2_1 Rrf2-type HTH domain signature. LrnaGLvkSirGayGGYvL |
Chain | Residue | Details |
A | LEU50-LEU68 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 138 |
Details | DNA_BIND: H-T-H motif => ECO:0000255|PROSITE-ProRule:PRU00540 |
Chain | Residue | Details |
A | LEU29-ASN52 | |
B | LEU29-ASN52 | |
C | LEU29-ASN52 | |
D | LEU29-ASN52 | |
E | LEU29-ASN52 | |
F | LEU29-ASN52 |