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2Y5J

Crystal structure of Burkholderia cenocepacia dihydropteroate synthase.

Functional Information from GO Data
ChainGOidnamespacecontents
A0004156molecular_functiondihydropteroate synthase activity
A0005829cellular_componentcytosol
A0009396biological_processfolic acid-containing compound biosynthetic process
A0016740molecular_functiontransferase activity
A0042558biological_processpteridine-containing compound metabolic process
A0044237biological_processcellular metabolic process
A0046654biological_processtetrahydrofolate biosynthetic process
A0046656biological_processfolic acid biosynthetic process
A0046872molecular_functionmetal ion binding
Functional Information from PDB Data
site_idAC1
Number of Residues4
DetailsBINDING SITE FOR RESIDUE EDO A 1293
ChainResidue
AHIS145
ALEU147
AHOH2085
AHOH2086

site_idAC2
Number of Residues8
DetailsBINDING SITE FOR RESIDUE EDO A 1294
ChainResidue
AASP271
ATHR275
AHOH2087
ASER231
ASER252
AVAL253
AVAL269
AHIS270

site_idAC3
Number of Residues8
DetailsBINDING SITE FOR RESIDUE EDO A 1295
ChainResidue
AARG20
APRO21
AVAL23
AVAL276
ALEU279
AHOH2016
AHOH2082
AHOH2088

site_idAC4
Number of Residues6
DetailsBINDING SITE FOR RESIDUE EDO A 1296
ChainResidue
AGLY12
AARG13
AGLY115
AALA116
AASP117
AASN138

Functional Information from PROSITE/UniProt
site_idPS00792
Number of Residues16
DetailsDHPS_1 Dihydropteroate synthase signature 1. VmGILNaTpDSFsDgG
ChainResidueDetails
AVAL23-GLY38

site_idPS00793
Number of Residues14
DetailsDHPS_2 Dihydropteroate synthase signature 2. GAdLLDIGGesTrP
ChainResidueDetails
AGLY57-PRO70

224931

PDB entries from 2024-09-11

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