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2Y4W

Solution structure of human ubiquitin conjugating enzyme Rad6b

Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0000209biological_processprotein polyubiquitination
A0000785cellular_componentchromatin
A0001701biological_processin utero embryonic development
A0001741cellular_componentXY body
A0004842molecular_functionubiquitin-protein transferase activity
A0005515molecular_functionprotein binding
A0005524molecular_functionATP binding
A0005634cellular_componentnucleus
A0005654cellular_componentnucleoplasm
A0005657cellular_componentreplication fork
A0005737cellular_componentcytoplasm
A0005886cellular_componentplasma membrane
A0006281biological_processDNA repair
A0006301biological_processpostreplication repair
A0006325biological_processchromatin organization
A0006511biological_processubiquitin-dependent protein catabolic process
A0006915biological_processapoptotic process
A0006974biological_processDNA damage response
A0007283biological_processspermatogenesis
A0007288biological_processsperm axoneme assembly
A0009410biological_processresponse to xenobiotic stimulus
A0009411biological_processresponse to UV
A0010845biological_processpositive regulation of reciprocal meiotic recombination
A0016020cellular_componentmembrane
A0016567biological_processprotein ubiquitination
A0016740molecular_functiontransferase activity
A0019787molecular_functionubiquitin-like protein transferase activity
A0031625molecular_functionubiquitin protein ligase binding
A0032446biological_processprotein modification by small protein conjugation
A0033503cellular_componentHULC complex
A0035234biological_processectopic germ cell programmed cell death
A0043066biological_processnegative regulation of apoptotic process
A0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
A0043951biological_processnegative regulation of cAMP-mediated signaling
A0045141biological_processmeiotic telomere clustering
A0050821biological_processprotein stabilization
A0051026biological_processchiasma assembly
A0051093biological_processnegative regulation of developmental process
A0051865biological_processprotein autoubiquitination
A0061631molecular_functionubiquitin conjugating enzyme activity
A0070193biological_processsynaptonemal complex organization
A0070534biological_processprotein K63-linked ubiquitination
A0070936biological_processprotein K48-linked ubiquitination
A0070979biological_processprotein K11-linked ubiquitination
A0090263biological_processpositive regulation of canonical Wnt signaling pathway
A1901874biological_processnegative regulation of post-translational protein modification
A2000242biological_processnegative regulation of reproductive process
Functional Information from PROSITE/UniProt
site_idPS00183
Number of Residues16
DetailsUBC_1 Ubiquitin-conjugating (UBC) active site signature. FHPNVyad.GsICLdiL
ChainResidueDetails
APHE77-LEU92

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsACT_SITE: Glycyl thioester intermediate => ECO:0000255|PROSITE-ProRule:PRU00388, ECO:0000255|PROSITE-ProRule:PRU10133
ChainResidueDetails
ACYS88

218853

PDB entries from 2024-04-24

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