2Y0M
CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN DOSAGE COMPENSATION FACTORS MSL1 AND MOF
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE ACO A 1450 |
| Chain | Residue |
| A | TRP192 |
| A | ARG325 |
| A | ARG326 |
| A | GLY327 |
| A | TYR328 |
| A | GLY329 |
| A | LYS330 |
| A | SER354 |
| A | LEU356 |
| A | SER360 |
| A | SER363 |
| A | PHE270 |
| A | TYR408 |
| A | LYS432 |
| A | HOH2009 |
| A | HOH2010 |
| A | LEU271 |
| A | ALA315 |
| A | CSO316 |
| A | ILE317 |
| A | LEU318 |
| A | THR319 |
| A | GLN324 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 1451 |
| Chain | Residue |
| A | CYS210 |
| A | CYS213 |
| A | HIS226 |
| A | CYS230 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0000305|PubMed:27183194 |
| Chain | Residue | Details |
| B | SER484 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton donor/acceptor => ECO:0000305|PubMed:21217699, ECO:0000305|PubMed:27768893, ECO:0000305|PubMed:33657400 |
| Chain | Residue | Details |
| A | GLU350 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:21217699, ECO:0000269|PubMed:21691301, ECO:0000269|PubMed:22020126, ECO:0000269|PubMed:27382063, ECO:0000269|PubMed:29321206, ECO:0000269|Ref.33, ECO:0007744|PDB:2GIV, ECO:0007744|PDB:2PQ8, ECO:0007744|PDB:2Y0M, ECO:0007744|PDB:3QAH, ECO:0007744|PDB:3TOA, ECO:0007744|PDB:3TOB, ECO:0007744|PDB:4DNC, ECO:0007744|PDB:5J8C, ECO:0007744|PDB:5J8F, ECO:0007744|PDB:5WCI |
| Chain | Residue | Details |
| A | CYS210 | |
| A | CYS213 | |
| A | HIS226 | |
| A | CYS230 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 7 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:29321206, ECO:0007744|PDB:5WCI |
| Chain | Residue | Details |
| A | ILE317 | |
| A | THR319 | |
| A | ARG325 | |
| A | GLY329 | |
| A | LYS330 | |
| A | SER354 | |
| A | SER363 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:21217699, ECO:0000269|Ref.33, ECO:0007744|PDB:2GIV, ECO:0007744|PDB:2Y0M |
| Chain | Residue | Details |
| A | ARG326 | |
| A | GLY327 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:21217699, ECO:0007744|PDB:2Y0M |
| Chain | Residue | Details |
| A | TYR408 | |
| A | LYS432 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | MOD_RES: N6-acetyllysine; by autocatalysis => ECO:0000269|PubMed:21217699, ECO:0000269|PubMed:21691301, ECO:0000269|PubMed:22020126, ECO:0000269|PubMed:22547026, ECO:0000269|PubMed:22918831, ECO:0000269|PubMed:27382063, ECO:0000269|Ref.33, ECO:0007744|PDB:2GIV |
| Chain | Residue | Details |
| A | ALY274 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | SER348 |
