2Y0F

STRUCTURE OF GCPE (IspG) FROM THERMUS THERMOPHILUS HB27

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005506	molecular_function	iron ion binding
A	0008299	biological_process	isoprenoid biosynthetic process
A	0016114	biological_process	terpenoid biosynthetic process
A	0016491	molecular_function	oxidoreductase activity
A	0019288	biological_process	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway
A	0046429	molecular_function	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity (ferredoxin)
A	0046872	molecular_function	metal ion binding
A	0051536	molecular_function	iron-sulfur cluster binding
A	0051539	molecular_function	4 iron, 4 sulfur cluster binding
A	0141197	molecular_function	4-hydroxy-3-methylbut-2-enyl-diphosphate synthase activity (flavodoxin)
B	0005506	molecular_function	iron ion binding
B	0008299	biological_process	isoprenoid biosynthetic process
B	0016114	biological_process	terpenoid biosynthetic process
B	0016491	molecular_function	oxidoreductase activity
B	0019288	biological_process	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway
B	0046429	molecular_function	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity (ferredoxin)
B	0046872	molecular_function	metal ion binding
B	0051536	molecular_function	iron-sulfur cluster binding
B	0051539	molecular_function	4 iron, 4 sulfur cluster binding
B	0141197	molecular_function	4-hydroxy-3-methylbut-2-enyl-diphosphate synthase activity (flavodoxin)
C	0005506	molecular_function	iron ion binding
C	0008299	biological_process	isoprenoid biosynthetic process
C	0016114	biological_process	terpenoid biosynthetic process
C	0016491	molecular_function	oxidoreductase activity
C	0019288	biological_process	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway
C	0046429	molecular_function	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity (ferredoxin)
C	0046872	molecular_function	metal ion binding
C	0051536	molecular_function	iron-sulfur cluster binding
C	0051539	molecular_function	4 iron, 4 sulfur cluster binding
C	0141197	molecular_function	4-hydroxy-3-methylbut-2-enyl-diphosphate synthase activity (flavodoxin)
D	0005506	molecular_function	iron ion binding
D	0008299	biological_process	isoprenoid biosynthetic process
D	0016114	biological_process	terpenoid biosynthetic process
D	0016491	molecular_function	oxidoreductase activity
D	0019288	biological_process	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway
D	0046429	molecular_function	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity (ferredoxin)
D	0046872	molecular_function	metal ion binding
D	0051536	molecular_function	iron-sulfur cluster binding
D	0051539	molecular_function	4 iron, 4 sulfur cluster binding
D	0141197	molecular_function	4-hydroxy-3-methylbut-2-enyl-diphosphate synthase activity (flavodoxin)

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE SF4 A 501

Chain	Residue
A	CYS297
A	PRO298
A	GLY299
A	CYS300
A	GLY342
A	CYS343
A	ASN346
A	GLU350
B	MET158

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SF4 B 501

Chain	Residue
A	MET158
B	CYS297
B	CYS300
B	CYS343
B	ASN346
B	GLU350

---

site_id	AC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SF4 C 501

Chain	Residue
C	CYS297
C	PRO298
C	CYS300
C	GLY342
C	CYS343
C	ASN346
C	GLU350
D	MET158

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site_id	AC4
Number of Residues	9
Details	BINDING SITE FOR RESIDUE SF4 D 501

Chain	Residue
C	MET158
D	CYS297
D	PRO298
D	GLY299
D	CYS300
D	GLY342
D	CYS343
D	ASN346
D	GLU350

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	16
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00159","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"21167158","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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