2XZG
Clathrin Terminal Domain Complexed with Pitstop 1
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005198 | molecular_function | structural molecule activity |
| A | 0006886 | biological_process | intracellular protein transport |
| A | 0016192 | biological_process | vesicle-mediated transport |
| A | 0030130 | cellular_component | clathrin coat of trans-Golgi network vesicle |
| A | 0030132 | cellular_component | clathrin coat of coated pit |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG A 1358 |
| Chain | Residue |
| A | PHE0 |
| A | GLY150 |
| A | SER171 |
| A | ALA172 |
| A | HOH2454 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PEG A 1359 |
| Chain | Residue |
| A | VAL190 |
| A | GLN192 |
| A | GLY234 |
| A | TRP164 |
| A | LEU183 |
| A | SER185 |
| A | ARG188 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 1360 |
| Chain | Residue |
| A | HIS129 |
| A | HOH2181 |
| A | HOH2203 |
| A | HOH2455 |
| A | HOH2456 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT A 1361 |
| Chain | Residue |
| A | LYS227 |
| A | VAL248 |
| A | ASP249 |
| site_id | AC5 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE VH1 A 1362 |
| Chain | Residue |
| A | ILE62 |
| A | ARG64 |
| A | ILE66 |
| A | LEU82 |
| A | GLN89 |
| A | PHE91 |
| A | ILE93 |
| A | LYS96 |
| A | GLN174 |
| A | HOH2007 |
| A | HOH2097 |
| A | HOH2103 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 43 |
| Details | Region: {"description":"WD40-like repeat 1"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 39 |
| Details | Region: {"description":"WD40-like repeat 2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 41 |
| Details | Region: {"description":"WD40-like repeat 3"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 45 |
| Details | Region: {"description":"WD40-like repeat 4"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 61 |
| Details | Region: {"description":"WD40-like repeat 5"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 43 |
| Details | Region: {"description":"WD40-like repeat 6"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 28 |
| Details | Region: {"description":"WD40-like repeat 7"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"FEB-2008","submissionDatabase":"UniProtKB","authors":["Bienvenut W.V.","Calvo F.","Matallanas D.","Cooper W.N.","Boldt K.","von Kriegsheim A.F.","Kolch W."]}},{"source":"PubMed","id":"22223895","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"25944712","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"Q68FD5","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"Q68FD5","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
