2XYI
Crystal Structure of Nurf55 in complex with a H4 peptide
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000122 | biological_process | negative regulation of transcription by RNA polymerase II |
| A | 0000785 | cellular_component | chromatin |
| A | 0000976 | molecular_function | transcription cis-regulatory region binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005667 | cellular_component | transcription regulator complex |
| A | 0005700 | cellular_component | polytene chromosome |
| A | 0006325 | biological_process | chromatin organization |
| A | 0006335 | biological_process | DNA replication-dependent chromatin assembly |
| A | 0006338 | biological_process | chromatin remodeling |
| A | 0006351 | biological_process | DNA-templated transcription |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0007307 | biological_process | eggshell chorion gene amplification |
| A | 0007346 | biological_process | regulation of mitotic cell cycle |
| A | 0007379 | biological_process | segment specification |
| A | 0016581 | cellular_component | NuRD complex |
| A | 0016589 | cellular_component | NURF complex |
| A | 0031491 | molecular_function | nucleosome binding |
| A | 0031507 | biological_process | heterochromatin formation |
| A | 0031523 | cellular_component | Myb complex |
| A | 0033186 | cellular_component | CAF-1 complex |
| A | 0034728 | biological_process | nucleosome organization |
| A | 0035097 | cellular_component | histone methyltransferase complex |
| A | 0035098 | cellular_component | ESC/E(Z) complex |
| A | 0042393 | molecular_function | histone binding |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0042826 | molecular_function | histone deacetylase binding |
| A | 0045892 | biological_process | negative regulation of DNA-templated transcription |
| A | 0045893 | biological_process | positive regulation of DNA-templated transcription |
| A | 0045944 | biological_process | positive regulation of transcription by RNA polymerase II |
| A | 0070822 | cellular_component | Sin3-type complex |
| A | 0090575 | cellular_component | RNA polymerase II transcription regulator complex |
| A | 0140718 | biological_process | facultative heterochromatin formation |
| B | 0046982 | molecular_function | protein heterodimerization activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE PG4 A 1416 |
| Chain | Residue |
| A | TYR185 |
| A | HOH2391 |
| A | ASP202 |
| A | GLU235 |
| A | ASP252 |
| A | PHE325 |
| A | HOH2225 |
| A | HOH2263 |
| A | HOH2264 |
| A | HOH2390 |
| site_id | AC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE PEG A 1417 |
| Chain | Residue |
| A | HOH2136 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PG4 A 1418 |
| Chain | Residue |
| A | LYS313 |
| A | HIS315 |
| A | SER316 |
| A | GLU318 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PG4 A 1419 |
| Chain | Residue |
| A | HIS240 |
| A | HIS243 |
| A | GLU290 |
| A | PHE291 |
| A | LEU307 |
| A | HOH2393 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PEG A 1420 |
| Chain | Residue |
| A | LEU314 |
| A | HOH2358 |
Functional Information from PROSITE/UniProt
| site_id | PS00678 |
| Number of Residues | 15 |
| Details | WD_REPEATS_1 Trp-Asp (WD) repeats signature. LLSAsdDhTICLWDI |
| Chain | Residue | Details |
| A | LEU197-ILE211 | |
| A | LEU293-LEU307 | |
| A | LEU337-LEU351 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 33 |
| Details | Repeat: {"description":"WD 1"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 31 |
| Details | Repeat: {"description":"WD 2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 31 |
| Details | Repeat: {"description":"WD 3"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 31 |
| Details | Repeat: {"description":"WD 4"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 31 |
| Details | Repeat: {"description":"WD 5"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 31 |
| Details | Repeat: {"description":"WD 6"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17372656","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"PubMed","id":"22389435","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
