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2XY6

Crystal structure of a salicylic aldehyde basepair in complex with fragment DNA polymerase I from Bacillus stearothermophilus

Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0003676molecular_functionnucleic acid binding
A0003677molecular_functionDNA binding
A0003887molecular_functionDNA-directed DNA polymerase activity
A0004527molecular_functionexonuclease activity
A0006139biological_processnucleobase-containing compound metabolic process
A0006259biological_processDNA metabolic process
A0006260biological_processDNA replication
A0006261biological_processDNA-templated DNA replication
A0006281biological_processDNA repair
A0006302biological_processdouble-strand break repair
A0008408molecular_function3'-5' exonuclease activity
A0034061molecular_functionDNA polymerase activity
A0046872molecular_functionmetal ion binding
A0071897biological_processDNA biosynthetic process
Functional Information from PDB Data
site_idAC1
Number of Residues4
DetailsBINDING SITE FOR RESIDUE SO4 A 1877
ChainResidue
AMET299
AALA300
AARG343
AARG677

site_idAC2
Number of Residues3
DetailsBINDING SITE FOR RESIDUE SO4 A 1878
ChainResidue
AHIS682
AARG702
ALYS706

site_idAC3
Number of Residues7
DetailsBINDING SITE FOR RESIDUE MES A 1879
ChainResidue
AGLU325
AARG375
AASP425
ATYR429
AARG435
AGLU321
AVAL322

site_idAC4
Number of Residues7
DetailsBINDING SITE FOR RESIDUE MRD A 1880
ChainResidue
ALYS381
ATRP382
AGLY384
APHE490
AASN700
AARG703
AHOH2112

Functional Information from PROSITE/UniProt
site_idPS00447
Number of Residues20
DetailsDNA_POLYMERASE_A DNA polymerase family A signature. RrqAKavnFGivYgiSdygL
ChainResidueDetails
AARG702-LEU721

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PDB entries from 2024-11-06

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