2XY3

Structure of the Bacillus subtilis prophage dUTPase with dUpNHpp

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0004170	molecular_function	dUTP diphosphatase activity
A	0006226	biological_process	dUMP biosynthetic process
A	0009117	biological_process	nucleotide metabolic process
A	0016787	molecular_function	hydrolase activity
A	0032991	cellular_component	protein-containing complex
A	0042802	molecular_function	identical protein binding
A	0046081	biological_process	dUTP catabolic process
A	0046872	molecular_function	metal ion binding
B	0000287	molecular_function	magnesium ion binding
B	0004170	molecular_function	dUTP diphosphatase activity
B	0006226	biological_process	dUMP biosynthetic process
B	0009117	biological_process	nucleotide metabolic process
B	0016787	molecular_function	hydrolase activity
B	0032991	cellular_component	protein-containing complex
B	0042802	molecular_function	identical protein binding
B	0046081	biological_process	dUTP catabolic process
B	0046872	molecular_function	metal ion binding
C	0000287	molecular_function	magnesium ion binding
C	0004170	molecular_function	dUTP diphosphatase activity
C	0006226	biological_process	dUMP biosynthetic process
C	0009117	biological_process	nucleotide metabolic process
C	0016787	molecular_function	hydrolase activity
C	0032991	cellular_component	protein-containing complex
C	0042802	molecular_function	identical protein binding
C	0046081	biological_process	dUTP catabolic process
C	0046872	molecular_function	metal ion binding
D	0000287	molecular_function	magnesium ion binding
D	0004170	molecular_function	dUTP diphosphatase activity
D	0006226	biological_process	dUMP biosynthetic process
D	0009117	biological_process	nucleotide metabolic process
D	0016787	molecular_function	hydrolase activity
D	0032991	cellular_component	protein-containing complex
D	0042802	molecular_function	identical protein binding
D	0046081	biological_process	dUTP catabolic process
D	0046872	molecular_function	metal ion binding
E	0000287	molecular_function	magnesium ion binding
E	0004170	molecular_function	dUTP diphosphatase activity
E	0006226	biological_process	dUMP biosynthetic process
E	0009117	biological_process	nucleotide metabolic process
E	0016787	molecular_function	hydrolase activity
E	0032991	cellular_component	protein-containing complex
E	0042802	molecular_function	identical protein binding
E	0046081	biological_process	dUTP catabolic process
E	0046872	molecular_function	metal ion binding
F	0000287	molecular_function	magnesium ion binding
F	0004170	molecular_function	dUTP diphosphatase activity
F	0006226	biological_process	dUMP biosynthetic process
F	0009117	biological_process	nucleotide metabolic process
F	0016787	molecular_function	hydrolase activity
F	0032991	cellular_component	protein-containing complex
F	0042802	molecular_function	identical protein binding
F	0046081	biological_process	dUTP catabolic process
F	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	BINDING SITE FOR RESIDUE DUP C 1129

Chain	Residue
B	ARG61
C	PRO93
C	MG1130
C	HOH2018
C	HOH2020
F	LYS101
B	SER62
B	SER63
B	GLN110
C	ASN74
C	ILE79
C	TYR83
C	TRP90
C	PHE91

---

site_id	AC2
Number of Residues	13
Details	BINDING SITE FOR RESIDUE DUP A 1130

Chain	Residue
A	ASN74
A	GLY77
A	ILE79
A	TYR83
A	TRP90
A	PHE91
A	PRO93
A	HOH2017
C	SER62
C	HOH2006
D	LYS101
D	LYS103
D	HOH2007

---

site_id	AC3
Number of Residues	11
Details	BINDING SITE FOR RESIDUE DUP D 1130

Chain	Residue
B	ASP31
B	LYS103
D	ASN74
D	ILE79
D	TYR83
D	PHE91
D	PRO93
D	HOH2020
D	HOH2021
D	HOH2022
F	SER62

---

site_id	AC4
Number of Residues	17
Details	BINDING SITE FOR RESIDUE DUP F 1129

Chain	Residue
A	LYS101
E	ARG61
E	SER62
E	SER63
E	GLN110
F	ASN74
F	GLY77
F	VAL78
F	ILE79
F	TYR83
F	TRP90
F	PHE91
F	PRO93
F	MG1130
F	HOH2014
F	HOH2015
F	HOH2016

---

site_id	AC5
Number of Residues	9
Details	BINDING SITE FOR RESIDUE DUP B 1129

Chain	Residue
A	SER62
A	HOH2011
B	ASN74
B	ILE79
B	TYR83
B	TRP90
B	PHE91
B	PRO93
E	LYS103

---

site_id	AC6
Number of Residues	14
Details	BINDING SITE FOR RESIDUE DUP E 1130

Chain	Residue
C	LYS101
D	ARG61
D	SER62
D	SER63
D	GLN110
E	ASN74
E	GLY77
E	TYR83
E	TRP90
E	PHE91
E	PRO93
E	MG1131
E	HOH2019
E	HOH2020

---

site_id	AC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG C 1130

Chain	Residue
C	DUP1129

---

site_id	AC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG E 1131

Chain	Residue
E	DUP1130

---

site_id	AC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG F 1130

Chain	Residue
F	DUP1129

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	ACT_SITE: Proton acceptor => ECO:0000305|PubMed:21358047, ECO:0000305|PubMed:23897460

Chain	Residue	Details
A	ASP80
B	ASP80
C	ASP80
D	ASP80
E	ASP80
F	ASP80

---

site_id	SWS_FT_FI2
Number of Residues	24
Details	BINDING: BINDING => ECO:0000269|PubMed:23897460, ECO:0007744|PDB:4AO5

Chain	Residue	Details
A	SER62
C	ASN74
C	TYR83
C	PHE91
D	SER62
D	ASN74
D	TYR83
D	PHE91
E	SER62
E	ASN74
E	TYR83
A	ASN74
E	PHE91
F	SER62
F	ASN74
F	TYR83
F	PHE91
A	TYR83
A	PHE91
B	SER62
B	ASN74
B	TYR83
B	PHE91
C	SER62

---