Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

2XWZ

STRUCTURE OF THE RECOMBINANT NATIVE NITRITE REDUCTASE FROM ALCALIGENES XYLOSOXIDANS complexed with nitrite

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005507	molecular_function	copper ion binding
A	0005515	molecular_function	protein binding
A	0016491	molecular_function	oxidoreductase activity
A	0019333	biological_process	denitrification pathway
A	0042128	biological_process	nitrate assimilation
A	0042597	cellular_component	periplasmic space
A	0046872	molecular_function	metal ion binding
A	0050421	molecular_function	nitrite reductase (NO-forming) activity
B	0005507	molecular_function	copper ion binding
B	0005515	molecular_function	protein binding
B	0016491	molecular_function	oxidoreductase activity
B	0019333	biological_process	denitrification pathway
B	0042128	biological_process	nitrate assimilation
B	0042597	cellular_component	periplasmic space
B	0046872	molecular_function	metal ion binding
B	0050421	molecular_function	nitrite reductase (NO-forming) activity
C	0005507	molecular_function	copper ion binding
C	0005515	molecular_function	protein binding
C	0016491	molecular_function	oxidoreductase activity
C	0019333	biological_process	denitrification pathway
C	0042128	biological_process	nitrate assimilation
C	0042597	cellular_component	periplasmic space
C	0046872	molecular_function	metal ion binding
C	0050421	molecular_function	nitrite reductase (NO-forming) activity
D	0005507	molecular_function	copper ion binding
D	0005515	molecular_function	protein binding
D	0016491	molecular_function	oxidoreductase activity
D	0019333	biological_process	denitrification pathway
D	0042128	biological_process	nitrate assimilation
D	0042597	cellular_component	periplasmic space
D	0046872	molecular_function	metal ion binding
D	0050421	molecular_function	nitrite reductase (NO-forming) activity
E	0005507	molecular_function	copper ion binding
E	0005515	molecular_function	protein binding
E	0016491	molecular_function	oxidoreductase activity
E	0019333	biological_process	denitrification pathway
E	0042128	biological_process	nitrate assimilation
E	0042597	cellular_component	periplasmic space
E	0046872	molecular_function	metal ion binding
E	0050421	molecular_function	nitrite reductase (NO-forming) activity
F	0005507	molecular_function	copper ion binding
F	0005515	molecular_function	protein binding
F	0016491	molecular_function	oxidoreductase activity
F	0019333	biological_process	denitrification pathway
F	0042128	biological_process	nitrate assimilation
F	0042597	cellular_component	periplasmic space
F	0046872	molecular_function	metal ion binding
F	0050421	molecular_function	nitrite reductase (NO-forming) activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CU A 1337

Chain	Residue
A	HIS89
A	CYS130
A	HIS139
A	MET144

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CU A 1338

Chain	Residue
A	ASP92
A	HIS94
A	HIS129
A	NO21339
E	HIS300

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE NO2 A 1339

Chain	Residue
A	ASP92
A	HIS94
A	HIS129
A	CU1338
E	HIS249
E	ILE251
E	HIS300

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 1340

Chain	Residue
A	GLY293
A	VAL294
A	HOH2269
D	LYS104

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ACT A 1341

Chain	Residue
A	GLY134
A	MET135
A	PRO137
A	TRP138
A	TYR197
E	GLU307

site_id	AC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE NO2 A 1342

Chain	Residue
A	HIS249
A	ILE251
A	HIS300
D	ASP92
D	HIS94
D	HIS129
D	CU1341

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 1343

Chain	Residue
A	VAL14
A	ALA15
A	HOH2010
A	HOH2270
A	HOH2271
A	HOH2272

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 1344

Chain	Residue
A	HIS22
A	GLU23
A	GLN24
A	HIS165
A	HOH2273

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 1345

Chain	Residue
A	GLN327
A	PRO331
A	HOH2274
D	HOH2092

site_id	BC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 A 1346

Chain	Residue
A	GLY223
A	HIS313

site_id	BC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 1347

Chain	Residue
A	PRO152
A	ARG153
A	ASP154
A	HOH2125
A	HOH2275

site_id	BC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 A 1348

Chain	Residue
A	GLY223
A	ALA224

site_id	BC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE ACT B 1337

Chain	Residue
B	GLY134
B	MET135
B	VAL136
B	PRO137
B	HOH2223
E	ARG336
E	HOH2266
F	PHE306

site_id	BC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CU B 1338

Chain	Residue
B	HIS89
B	CYS130
B	HIS139
B	MET144

site_id	BC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CU B 1339

Chain	Residue
B	ASP92
B	HIS94
B	HIS129
B	NO21341
F	HIS300

site_id	BC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 B 1340

Chain	Residue
B	GLU23
B	GLN24
B	HIS165

site_id	BC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE NO2 B 1341

Chain	Residue
B	ASP92
B	HIS94
B	HIS129
B	CU1339
F	HIS249
F	ILE251
F	HIS300

site_id	BC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ACT B 1342

Chain	Residue
B	GLY134
B	MET135
B	PRO137
B	TRP138
B	TYR197
F	GLU307

site_id	CC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE ACT B 1343

Chain	Residue
B	ASP121
B	ARG122
B	HOH2058
B	HOH2224
F	ARG270
F	LYS290
F	SO41340

site_id	CC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 B 1344

Chain	Residue
B	HOH2225
B	HOH2226
B	VAL14
B	ALA15

site_id	CC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 B 1345

Chain	Residue
B	ARG270
B	HOH2227
B	HOH2228
B	HOH2229

site_id	CC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 B 1346

Chain	Residue
B	GLY223
B	HIS313

site_id	CC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 B 1347

Chain	Residue
B	SER28
B	LYS31
B	HOH2230

site_id	CC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 B 1348

Chain	Residue
B	PRO152
B	ARG153
B	ASP154
B	HOH2101
B	HOH2231

site_id	CC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 B 1349

Chain	Residue
B	GLN327
B	PRO331
B	HOH2232
C	HOH2090

site_id	CC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 B 1350

Chain	Residue
B	GLY293
B	VAL294
B	HOH2233
C	LYS104

site_id	CC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ACT C 1337

Chain	Residue
B	GLU307
C	MET135
C	PRO137
C	TRP138
C	TYR197

site_id	DC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CU C 1338

Chain	Residue
C	HIS89
C	CYS130
C	HIS139
C	MET144

site_id	DC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CU C 1339

Chain	Residue
B	HIS300
C	ASP92
C	HIS94
C	HIS129
C	NO1347

site_id	DC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 C 1341

Chain	Residue
C	ARG270
C	HOH2202

site_id	DC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 C 1342

Chain	Residue
C	ALA15
C	HOH2014
C	HOH2019
C	HOH2252

site_id	DC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 C 1343

Chain	Residue
C	GLY293
C	VAL294
C	HOH2253
C	HOH2254
C	HOH2255
F	LYS104

site_id	DC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 C 1344

Chain	Residue
C	GLN327
C	HOH2248
C	HOH2256
C	HOH2257

site_id	DC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 C 1345

Chain	Residue
C	GLN24
C	HIS165

site_id	DC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 C 1346

Chain	Residue
C	ARG153
C	ASP154
C	HOH2258

site_id	DC9
Number of Residues	7
Details	BINDING SITE FOR RESIDUE NO C 1347

Chain	Residue
B	HIS249
B	ILE251
B	HIS300
C	ASP92
C	HIS94
C	HIS129
C	CU1339

site_id	EC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 D 1337

Chain	Residue
D	GLY223
D	HIS313
D	HOH2250

site_id	EC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE ACT D 1338

Chain	Residue
A	GLU307
D	GLY134
D	MET135
D	PRO137
D	TRP138
D	TYR197
D	MET204

site_id	EC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ACT D 1339

Chain	Residue
D	LYS104
D	ASN107
D	HOH2093
D	HOH2112

site_id	EC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CU D 1340

Chain	Residue
D	HIS89
D	CYS130
D	HIS139
D	MET144

site_id	EC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CU D 1341

Chain	Residue
A	HIS300
A	NO21342
D	HIS94
D	HIS129

site_id	EC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 D 1343

Chain	Residue
D	GLY293
D	VAL294
D	HOH2251
E	LYS104

site_id	EC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 D 1344

Chain	Residue
D	ARG270
E	ACT1339
E	HOH2268

site_id	EC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 D 1345

Chain	Residue
D	GLN327
D	PRO331
D	HOH2253
E	HOH2097

site_id	EC9
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 D 1346

Chain	Residue
A	ARG270
A	ASP271
A	LYS290
D	ASP121
D	ARG122
D	HOH2254
D	HOH2255

site_id	FC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 D 1347

Chain	Residue
D	LYS42
D	MET44
D	HOH2256
D	HOH2257

site_id	FC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 D 1348

Chain	Residue
D	HIS22
D	GLU23
D	GLN24
D	HIS165
D	HOH2258
D	HOH2259
D	HOH2260

site_id	FC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 D 1349

Chain	Residue
D	PRO152
D	ARG153
D	ASP154
D	HOH2122
D	HOH2261

site_id	FC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 D 1350

Chain	Residue
D	VAL14
D	ALA15
D	HOH2013
D	HOH2015

site_id	FC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ACT E 1337

Chain	Residue
D	GLU307
E	GLY134
E	MET135
E	PRO137
E	TRP138
E	TYR197

site_id	FC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE ACT E 1338

Chain	Residue
C	ARG336
D	PHE306
E	GLY134
E	MET135
E	VAL136
E	PRO137
E	HOH2267

site_id	FC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE ACT E 1339

Chain	Residue
D	ARG270
D	LYS290
D	SO41344
E	ASP121
E	ARG122
E	HOH2268
E	HOH2269

site_id	FC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CU E 1340

Chain	Residue
E	HIS89
E	CYS130
E	HIS139
E	MET144

site_id	FC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CU E 1341

Chain	Residue
D	HIS300
E	ASP92
E	HIS94
E	HIS129
E	NO1349

site_id	GC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 E 1342

Chain	Residue
E	HIS22
E	GLU23
E	GLN24
E	HIS165
E	HOH2270
E	HOH2271

site_id	GC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 E 1343

Chain	Residue
E	ARG270
E	HOH2272

site_id	GC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 E 1344

Chain	Residue
E	VAL14
E	ALA15

site_id	GC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 E 1345

Chain	Residue
E	SER28
E	GLY29
E	LYS31
E	HOH2274

site_id	GC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 E 1346

Chain	Residue
A	HOH2099
E	GLN327
E	PRO331
E	HOH2262
E	HOH2275

site_id	GC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 E 1347

Chain	Residue
E	ARG153
E	ASP154
E	HOH2276

site_id	GC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 E 1348

Chain	Residue
A	LYS104
E	GLY293
E	VAL294
E	HOH2277

site_id	GC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE NO E 1349

Chain	Residue
D	HIS249
D	ILE251
D	HIS300
E	ASP92
E	HIS94
E	HIS129
E	CU1341

site_id	GC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ACT F 1336

Chain	Residue
C	GLU307
F	GLY134
F	MET135
F	PRO137
F	TRP138
F	TYR197

site_id	HC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CU F 1337

Chain	Residue
F	HIS89
F	CYS130
F	HIS139
F	MET144

site_id	HC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CU F 1338

Chain	Residue
C	HIS300
F	HIS94
F	HIS129
F	NO21339

site_id	HC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE NO2 F 1339

Chain	Residue
C	HIS249
C	ILE251
C	HIS300
F	ASP92
F	HIS94
F	HIS129
F	CU1338

site_id	HC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 F 1340

Chain	Residue
B	ACT1343
B	HOH2224
F	ARG270
F	HOH2258
F	HOH2259

site_id	HC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 F 1341

Chain	Residue
B	LYS104
F	GLY293
F	VAL294
F	HOH2260

site_id	HC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 F 1342

Chain	Residue
F	PRO152
F	ARG153
F	ASP154
F	HOH2262

site_id	HC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 F 1343

Chain	Residue
B	HOH2082
F	GLN327
F	PRO331
F	HOH2254

site_id	HC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 F 1344

Chain	Residue
F	VAL14
F	ALA15

site_id	HC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 F 1345

Chain	Residue
F	HIS22
F	GLU23
F	GLN24
F	HIS165
F	HOH2266

site_id	IC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 F 1346

Chain	Residue
F	GLY223
F	HIS313
F	LYS315

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)