2XVI
Crystal structure of the mutant bacterial flavin containing monooxygenase (Y207S)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0004499 | molecular_function | N,N-dimethylaniline monooxygenase activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016709 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen |
| A | 0034899 | molecular_function | trimethylamine monooxygenase activity |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| A | 0050661 | molecular_function | NADP binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004497 | molecular_function | monooxygenase activity |
| B | 0004499 | molecular_function | N,N-dimethylaniline monooxygenase activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016709 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen |
| B | 0034899 | molecular_function | trimethylamine monooxygenase activity |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| B | 0050661 | molecular_function | NADP binding |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0004497 | molecular_function | monooxygenase activity |
| C | 0004499 | molecular_function | N,N-dimethylaniline monooxygenase activity |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0016709 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen |
| C | 0034899 | molecular_function | trimethylamine monooxygenase activity |
| C | 0042802 | molecular_function | identical protein binding |
| C | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| C | 0050661 | molecular_function | NADP binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE FAD A 1448 |
| Chain | Residue |
| A | GLY9 |
| A | TRP47 |
| A | HIS63 |
| A | MET66 |
| A | SER72 |
| A | ASN73 |
| A | THR124 |
| A | ALA125 |
| A | VAL126 |
| A | CYS161 |
| A | THR162 |
| A | GLY11 |
| A | GLY163 |
| A | PHE165 |
| A | PHE280 |
| A | GLN318 |
| A | SER321 |
| A | PHE325 |
| A | OXY1451 |
| A | HOH2002 |
| A | HOH2047 |
| A | HOH2049 |
| A | PRO12 |
| A | SER13 |
| A | GLU38 |
| A | LYS39 |
| A | GLN40 |
| A | GLY45 |
| A | GLN46 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE NO3 A 1449 |
| Chain | Residue |
| A | HIS185 |
| A | ALA186 |
| A | SER206 |
| A | SER208 |
| A | CYS271 |
| A | THR272 |
| A | GLY273 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MES A 1450 |
| Chain | Residue |
| A | ASN290 |
| C | ARG19 |
| C | GLN22 |
| C | GLU26 |
| C | LYS113 |
| C | ALA114 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE OXY A 1451 |
| Chain | Residue |
| A | ASN73 |
| A | TRP319 |
| A | FAD1448 |
| A | HOH2041 |
| A | HOH2049 |
| site_id | AC5 |
| Number of Residues | 28 |
| Details | BINDING SITE FOR RESIDUE FAD B 1448 |
| Chain | Residue |
| B | GLY9 |
| B | GLY11 |
| B | PRO12 |
| B | SER13 |
| B | GLU38 |
| B | LYS39 |
| B | GLN40 |
| B | GLY45 |
| B | GLN46 |
| B | TRP47 |
| B | HIS63 |
| B | MET66 |
| B | SER72 |
| B | ASN73 |
| B | LEU79 |
| B | THR124 |
| B | ALA125 |
| B | VAL126 |
| B | CYS161 |
| B | THR162 |
| B | GLY163 |
| B | PHE165 |
| B | GLN318 |
| B | SER321 |
| B | PHE322 |
| B | HOH2023 |
| B | HOH2025 |
| B | HOH2039 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE NO3 B 1449 |
| Chain | Residue |
| B | HIS185 |
| B | ALA186 |
| B | SER206 |
| B | SER208 |
| B | CYS271 |
| B | THR272 |
| B | GLY273 |
| B | TYR274 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MES B 1450 |
| Chain | Residue |
| B | ARG19 |
| B | GLN22 |
| B | GLU26 |
| B | LYS113 |
| B | ALA114 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE OXY B 1451 |
| Chain | Residue |
| B | ASN73 |
| B | TRP319 |
| site_id | AC9 |
| Number of Residues | 27 |
| Details | BINDING SITE FOR RESIDUE FAD C 1448 |
| Chain | Residue |
| C | TRP47 |
| C | HIS63 |
| C | MET66 |
| C | SER72 |
| C | ASN73 |
| C | LEU79 |
| C | THR124 |
| C | ALA125 |
| C | VAL126 |
| C | CYS161 |
| C | THR162 |
| C | GLY163 |
| C | PHE165 |
| C | GLN318 |
| C | SER321 |
| C | PHE325 |
| C | HOH2011 |
| C | HOH2012 |
| C | GLY9 |
| C | GLY11 |
| C | PRO12 |
| C | SER13 |
| C | GLU38 |
| C | LYS39 |
| C | GLN40 |
| C | GLY45 |
| C | GLN46 |
| site_id | BC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE NO3 C 1449 |
| Chain | Residue |
| C | HIS185 |
| C | ALA186 |
| C | SER206 |
| C | SER208 |
| C | ALA209 |
| C | CYS271 |
| C | THR272 |
| C | GLY273 |
| site_id | BC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE OXY C 1450 |
| Chain | Residue |
| C | ASN73 |
| C | GLN318 |
| C | TRP319 |
