2XVH
Crystal structure of bacterial flavin containing monooxygenase in complex with NADP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0004499 | molecular_function | N,N-dimethylaniline monooxygenase activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016709 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| A | 0050661 | molecular_function | NADP binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004497 | molecular_function | monooxygenase activity |
| B | 0004499 | molecular_function | N,N-dimethylaniline monooxygenase activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016709 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| B | 0050661 | molecular_function | NADP binding |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0004497 | molecular_function | monooxygenase activity |
| C | 0004499 | molecular_function | N,N-dimethylaniline monooxygenase activity |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0016709 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen |
| C | 0042802 | molecular_function | identical protein binding |
| C | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| C | 0050661 | molecular_function | NADP binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 32 |
| Details | BINDING SITE FOR RESIDUE FAD A 1448 |
| Chain | Residue |
| A | GLY9 |
| A | TRP47 |
| A | HIS63 |
| A | SER65 |
| A | MET66 |
| A | SER72 |
| A | ASN73 |
| A | LEU79 |
| A | THR124 |
| A | VAL126 |
| A | CYS161 |
| A | GLY11 |
| A | THR162 |
| A | GLY163 |
| A | PHE165 |
| A | GLN318 |
| A | SER321 |
| A | PHE325 |
| A | NAP1449 |
| A | HOH2001 |
| A | HOH2038 |
| A | HOH2053 |
| A | PRO12 |
| A | HOH2054 |
| A | HOH2055 |
| A | HOH2056 |
| A | SER13 |
| A | GLU38 |
| A | LYS39 |
| A | GLN40 |
| A | GLY45 |
| A | GLN46 |
| site_id | AC2 |
| Number of Residues | 32 |
| Details | BINDING SITE FOR RESIDUE FAD B 1447 |
| Chain | Residue |
| B | GLY9 |
| B | GLY11 |
| B | PRO12 |
| B | SER13 |
| B | PHE37 |
| B | GLU38 |
| B | LYS39 |
| B | GLN40 |
| B | GLY45 |
| B | GLN46 |
| B | TRP47 |
| B | HIS63 |
| B | SER65 |
| B | MET66 |
| B | SER72 |
| B | ASN73 |
| B | LEU79 |
| B | THR124 |
| B | ALA125 |
| B | VAL126 |
| B | CYS161 |
| B | THR162 |
| B | GLY163 |
| B | PHE165 |
| B | GLN318 |
| B | SER321 |
| B | PHE322 |
| B | NAP1449 |
| B | HOH2010 |
| B | HOH2051 |
| B | HOH2081 |
| B | HOH2082 |
| site_id | AC3 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE FAD C 1448 |
| Chain | Residue |
| C | GLY9 |
| C | GLY11 |
| C | PRO12 |
| C | SER13 |
| C | GLU38 |
| C | LYS39 |
| C | GLN40 |
| C | GLY45 |
| C | GLN46 |
| C | TRP47 |
| C | HIS63 |
| C | SER65 |
| C | MET66 |
| C | SER72 |
| C | ASN73 |
| C | THR124 |
| C | ALA125 |
| C | VAL126 |
| C | CYS161 |
| C | THR162 |
| C | GLY163 |
| C | PHE165 |
| C | GLN318 |
| C | SER321 |
| C | PHE322 |
| C | NAP1450 |
| C | HOH2035 |
| C | HOH2045 |
| C | HOH2053 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MES C 1449 |
| Chain | Residue |
| B | TYR151 |
| C | ARG121 |
| C | TYR151 |
| C | GLU153 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 1448 |
| Chain | Residue |
| B | PHE122 |
| B | HOH2009 |
| C | THR146 |
| B | ILE120 |
| B | ARG121 |
| site_id | AC6 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE NAP A 1449 |
| Chain | Residue |
| A | TYR67 |
| A | TRP71 |
| A | ASN73 |
| A | PHE165 |
| A | TYR169 |
| A | SER205 |
| A | SER206 |
| A | TYR207 |
| A | SER208 |
| A | ASP211 |
| A | ARG229 |
| A | THR230 |
| A | ASN246 |
| A | CYS271 |
| A | THR272 |
| A | GLY273 |
| A | TYR274 |
| A | ARG412 |
| A | FAD1448 |
| A | HOH2018 |
| A | HOH2025 |
| A | HOH2057 |
| A | HOH2058 |
| A | HOH2059 |
| site_id | AC7 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE NAP B 1449 |
| Chain | Residue |
| B | TYR67 |
| B | TRP71 |
| B | ASN73 |
| B | PHE165 |
| B | TYR169 |
| B | VAL203 |
| B | SER205 |
| B | SER206 |
| B | TYR207 |
| B | SER208 |
| B | ASP211 |
| B | ARG229 |
| B | THR230 |
| B | ASN246 |
| B | CYS271 |
| B | THR272 |
| B | TYR274 |
| B | ARG412 |
| B | FAD1447 |
| B | HOH2064 |
| B | HOH2083 |
| B | HOH2084 |
| site_id | AC8 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE NAP C 1450 |
| Chain | Residue |
| C | TYR67 |
| C | LEU70 |
| C | TRP71 |
| C | ASN73 |
| C | PRO171 |
| C | VAL203 |
| C | SER205 |
| C | SER206 |
| C | TYR207 |
| C | SER208 |
| C | ASP211 |
| C | ARG229 |
| C | THR230 |
| C | ASN246 |
| C | CYS271 |
| C | THR272 |
| C | GLY273 |
| C | ARG412 |
| C | FAD1448 |
| C | HOH2054 |
| C | HOH2055 |
| C | HOH2056 |
