2XVA
Crystal structure of the tellurite detoxification protein TehB from E. coli in complex with sinefungin
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0008757 | molecular_function | S-adenosylmethionine-dependent methyltransferase activity |
| A | 0009636 | biological_process | response to toxic substance |
| A | 0016740 | molecular_function | transferase activity |
| A | 0032259 | biological_process | methylation |
| A | 0046677 | biological_process | response to antibiotic |
| A | 0046690 | biological_process | response to tellurium ion |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0008168 | molecular_function | methyltransferase activity |
| B | 0008757 | molecular_function | S-adenosylmethionine-dependent methyltransferase activity |
| B | 0009636 | biological_process | response to toxic substance |
| B | 0016740 | molecular_function | transferase activity |
| B | 0032259 | biological_process | methylation |
| B | 0046677 | biological_process | response to antibiotic |
| B | 0046690 | biological_process | response to tellurium ion |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005829 | cellular_component | cytosol |
| C | 0008168 | molecular_function | methyltransferase activity |
| C | 0008757 | molecular_function | S-adenosylmethionine-dependent methyltransferase activity |
| C | 0009636 | biological_process | response to toxic substance |
| C | 0016740 | molecular_function | transferase activity |
| C | 0032259 | biological_process | methylation |
| C | 0046677 | biological_process | response to antibiotic |
| C | 0046690 | biological_process | response to tellurium ion |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005829 | cellular_component | cytosol |
| D | 0008168 | molecular_function | methyltransferase activity |
| D | 0008757 | molecular_function | S-adenosylmethionine-dependent methyltransferase activity |
| D | 0009636 | biological_process | response to toxic substance |
| D | 0016740 | molecular_function | transferase activity |
| D | 0032259 | biological_process | methylation |
| D | 0046677 | biological_process | response to antibiotic |
| D | 0046690 | biological_process | response to tellurium ion |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE SFG A 1198 |
| Chain | Residue |
| A | GLY38 |
| A | ASN88 |
| A | THR102 |
| A | VAL103 |
| A | VAL104 |
| A | LEU108 |
| A | HOH2050 |
| A | HOH2076 |
| A | HOH2180 |
| A | HOH2181 |
| A | HOH2182 |
| A | GLY40 |
| A | HOH2183 |
| A | HOH2184 |
| A | ARG43 |
| A | ASN44 |
| A | ASP59 |
| A | LYS60 |
| A | VAL85 |
| A | ASP86 |
| A | LEU87 |
| site_id | AC2 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE SFG B 1198 |
| Chain | Residue |
| B | GLY38 |
| B | GLY40 |
| B | ARG43 |
| B | ASN44 |
| B | ASP59 |
| B | LYS60 |
| B | VAL85 |
| B | ASP86 |
| B | LEU87 |
| B | ASN88 |
| B | THR102 |
| B | VAL103 |
| B | VAL104 |
| B | LEU108 |
| B | HOH2051 |
| B | HOH2200 |
| B | HOH2201 |
| B | HOH2202 |
| B | HOH2203 |
| B | HOH2204 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ZN B 1199 |
| Chain | Residue |
| B | HIS19 |
| B | SER20 |
| site_id | AC4 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE SFG C 1197 |
| Chain | Residue |
| C | GLY38 |
| C | GLY40 |
| C | ARG43 |
| C | ASN44 |
| C | ASP59 |
| C | LYS60 |
| C | VAL85 |
| C | ASP86 |
| C | LEU87 |
| C | ASN88 |
| C | THR102 |
| C | VAL103 |
| C | VAL104 |
| C | LEU108 |
| C | HOH2039 |
| C | HOH2041 |
| C | HOH2199 |
| C | HOH2200 |
| C | HOH2201 |
| C | HOH2202 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE ZN C 1198 |
| Chain | Residue |
| C | SER20 |
| site_id | AC6 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE SFG D 1198 |
| Chain | Residue |
| D | GLY38 |
| D | GLY40 |
| D | ARG43 |
| D | ASN44 |
| D | ASP59 |
| D | LYS60 |
| D | VAL85 |
| D | ASP86 |
| D | LEU87 |
| D | ASN88 |
| D | THR102 |
| D | VAL103 |
| D | VAL104 |
| D | LEU108 |
| D | HOH2033 |
| D | HOH2168 |
| D | HOH2169 |
| D | HOH2170 |
| D | HOH2171 |
| D | HOH2172 |
| D | HOH2173 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE ZN D 1199 |
| Chain | Residue |
| D | SER20 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Region: {"description":"S-adenosyl-L-methionine"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | Binding site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
